Calcium Stella Vitamin C, PP treatment treatment for rickets and calcium supplements (3 blisters x 8 tubes x 10ml)

Pharmacy

calcium needed to maintain the function of the nervous system, muscle, bone, bone and capillary membrane. Cation is an important active factor in the many anti -enzymes and is essential for a number of biological processes that include nerve impulses, heart muscle contraction, smooth muscle and skeletal muscle; Kidney function, respiratory and coagulation. Calcium also plays the role of regulating the release and storage of nerve impulses and hormones, absorbing and connecting amino acids, absorbing cyanocobalamin vitamin B and gastrin secretion.

Vitamin C has the ability to eliminate in many oxidative and redox biological reactions. There are some biological functions of Vitamin C that have been clearly verified, including collagen, carnitin, catecholarin, tyrosin, cortisteroid and aldosteron. Vitamin C has also participated as "A reducing agent in the Microsom metabolic enzyme system along with Cytochrom P450. The activity of the drug metabolic enzyme system in microsom will be reduced without vitamin C. Vitamin C also regulates absorption, transportation and reserves of iron. Vitamin C is an effective antioxidant protection. Reactive Nitrogen Species such as Hydroxy, Peroxy, Superoxyd, Per Oxyrnitrit and Vitroxyd), single oxygen and hypoclorite, are free radicals that are toxic to the body.

In the body, nicotinamide is made up of nicotinic acid, nicotinamide performs function after converting or nicotiarie algerning dcleotide (NAD) or Nicotinamide Adenine Dinucleotide phosphate (NADP). NAD and NADP have a vital role in metabolism, as an oxidative - redox catalyst that is necessary for cell respiration, glycogen resolution, and lipid metabolism. Among these reactions, these coenzymes act as hydrogen transport molecules, Nicotinamide deficiency can occur with the lack of other B vitamins and can cause Pellagra.

pharmacokinetic pharmacokinetics

calcium is absorbed mainly through the small intestine thanks to the active transportation mechanism and passive diffusion. About one -third of the calcium is absorbed, although this rate may vary depending on the diet and the condition of the small intestine, in addition to increased calcium's absorption in case of calcium deficiency and in high physiological needs such as childhood or pregnancy and breastfeeding. The excess calcium is excreted mainly through the kidneys. The amount of calcium is not absorbed with the amount of secretion into the bile and pancreatic fluid is eliminated into the feces. A small amount is lost through sweat, skin, hair and nails. Calcium through the placenta and distributed to the mother.

Vitamin C is easily absorbed through the gastrointestinal tract and widely allocated in body tissues. The plasma concentration of vitamin C increases when the oral dose increases until the stabilization state is about 90 - 150 mg/day. The reserve of vitamin C in a healthy body is about 1.5 g although it can reserve more when the amount is over 200 mg/day. The concentration of medication in leukemia and platelets is higher in red blood cells and plasma. Vitamin C is reversible to oxidize to dehydroorscorbic acid, some are converted into non-active Sobat-2-Sulfate and oxalic acids are excreted in urine. The amount of vitamin C exceeding the needs of the body is also quickly eliminated in the form of unchanged urine, this is usually released when the amount exceeds 200 mg/day. Vitamin C through the placenta and is distributed to the mother. The drug is excluded by hematoma.

Vitamin PP (Nicotinamide) is easily absorbed through the gastrointestinal tract after drinking and widely distributed into the body tissue. The main metabolic path is transformed into n-methylnicotinamid and the derivatives of 2 pyridon and 4-pyridon, nicotinuric acid are also formed. A small amount of nicotinamide is excreted in the form of unchanged urine gifts after taking therapy; However, when the dose is larger, the amount of drug excreted in the form of unchanged will increase.

Avoid high doses of vitamin C for patients:

Caution when using

calcium stella vitamin C, PP contains sodium sulfit, rarely causing hypersensory reactions and bronchospasm.

Pay attention to the content of saccharose (2.5 g/5 ml) and sodium content when prescribed for patients with diabetes and salt patients. This drug should not be used for diseases with rare genetic problems that are fructose intolerance, glucose-galactose absorbent or enzyme deficiency sucrase-isormaltase.

Be careful to use calcium salt for patients with renal impairment or diseases related to hypercalcemia such as sarcoid disease and some malignant tumors.

Located vitamin C long dose can lead to an increase in metabolism of the drug (greasy phenomenon), until the normal dose decreases, it will lead to scorout. High doses of vitamin C during pregnancy can lead to scorbut disease for babies.

Hematopsius can occur when using vitamin C for babies with glucose -6 -deficiency - Phosphate denydrogeriase and other healthy premature babies. Nicotinamide should be used for patients with a history of stomach ulcers and patients with diabetes, gout or liver failure.

The ability to drive and operate machinery

no effect.

Pregnancy

Calcium stella vitamin C, PP is not harmful when using the daily recommended dosage daily (10 - 20 ml x 2 times/day in the morning and lunch). However, pregnant women should be provided with adequate diet. Using too many vitamins and other minerals can be harmful to the fetus or mother. Vitamin C and Nicotinamide with additional supplements are often considered safe during pregnancy when using the recommended dose.

Breastfeeding period

No reports.

Calcium stella vitamin C, PP is not harmful when using the daily recommended dosage daily (10 - 20 ml x 2 times/day in the morning and noon).

Drug interaction

Drug interaction

Tetracyclin: Tetracyclin and calcium stella vitamin C, PP should be used at least 3 hours apart to avoid calcium affecting the absorption of tetracyclin.

digitalis: Like all preparations containing calcium, using calcium stella vitamin C, PP at the same time with digitalis can increase the toxicity of digitalis.

diphosphonate: There is a risk of reducing the absorption of diphosphonate in the digestive tract. Therefore, taking two drugs at least 2 hours apart.

Thiazid diuretics: may increase blood calcium due to the calcium elimination rig in the kidneys, need to be cautious when coordinating treatment.

Simultaneously use vitamin C with aspirin increases the secretion of vitamin C and reduces apirin excretion through urine.

Simultaneously use vitamin C and fluphenazin coal to reduce fluphenazin levels in plasma. The acidification of urine after using vitamin C can change the excretion of other drugs.

Vitamin C is a powerful reducing agent, which affects many tests based on redox reactions. The presence of vitamin C in urine increases the amount of glucose if quantitative with copper sulfate reagent and false reduction of glucose amount if quantitative by oxidase glucose method.

The risk of muscle disease or muscular award may increase when taking nicotinamide along with statin medications.

Nicotinamide may increase the need for insulin or oral hypoglycemic drugs.

Aspirin can reduce the clearance of nicotinamide.

Nicotinamide may increase the effects of lymphadenopathy and vasoconstrictors that lead to vertical hypotension.

Tyeum of drugs

Due to the absence of studies on the correlation of the drug, not mixing this drug with other drugs.