Candid-V3 Glenmark vaginal placement treats Candida infection (1 blister x 3 tablets)

Dosage form Box of 1 blister x 3 tablets
Specifications Clotrimazole
Ingredient Glenmark Pharmaceuticals Ltd.

Ingredient

Composition information	Content
Clotrimazole	200mg

Uses

indications

Candid V3 drugs are indicated for treatment at the cantonic treatment of vulva - vaginal infection (etc.). Clotrimazol is a chosen medicine to treat vaginal candidiasis.

Pharmacokic

Clotrimazol is an imidazol conductor that has an anti -fungal effect due to sterol synthesis of sterols. It inhibits the transfer of 2,4 - methylenedihydrolanosterol into demethylsterol, the precursor of ergosterol, a major component that makes the mushroom cytoplasmic membrane.

In minimum inhibitor, clotrimazol causes leakage of internal cell phosphorus into the surrounding environment and breaks nucleic acids and increases potassium escape. It also causes leaks of intracellular loving substances that lead to inhibition of molecules synthesis such as protein, lipid, DNA and polysaccharid.

Other antifungal effects of Clotrimazol include influencing cell membranes, other enzymes of cell membranes, affecting the transportation through cell membranes and passing fatty acids.

Antibiotic spectrum:

mushrooms:

Clotrimazol is a broad -spectrum antivirus that inhibits the growth of most pathogenic fungi in humans including the following types:

a) Blastomyces dermatitidis

b) Candida spp: Clotrimazol works against Candida spp. Like nystatin

c) Coccidioides Immitis

d) Cryptococcus NeOForans (Torula Histolytica)

e) dermatophytes (trichophyton, microsporum, epidermophyton)

f) Histoplasma capsulatum

g) Malassezia Furfur

h) Naegleria Fowleri

1) Nocardia spp

j) paracoccidioides brasiliensis

k) Sportotrichum Schenckii

Dynamic pharmacokinetics

Survey on pharmacokinetics of Clotrimazol vagina shows only a small amount (3 - 10% of the dose) is absorbed. Because the amount of clotrimazol absorption is rapidly metabolized through the liver into a pharmaceutical and non -pharmacological metabolic substance, the peak concentration of the plasma of clotrimazol after placing the 500 mg vagina is less than 10 ng/ml, this shows that the Clotrimazol pellet places the vagina that does not cause systemic effects or side effects.

Before taking Candid-V3 Glenmark vaginal placement treats Candida infection (1 blister x 3 tablets)

How to use

Instructions on how to use the drug stick:

Pull the stick A (the middle stick) out of all the way. Put 1 tablet in a tube b. It is best to put on your back. Remove the drug. Rinse with negative water and let dry.

Put a Candid V3 tablet as deep as possible into the vagina, preferably when going to bed in the evening. Should lie on your back, legs to get a little high and use the instrument to put the medicine in.

Do not take the drug during menstruation, when using the drug, remember to end the treatment before the first period.

For good effect, recommend applying Candid V gel in the vagina around the vagina. Watch out for re -infection, a partner must also be treated with cream or candid gel. Candid V3 tablets are colorless and not dirty.

used for children:

Do not use Candid V3 vagina for children under 16.

Treatment time:

Control and prevention center (CDC) recommends using Clotrimazol vagina as follows:

VVC has no complications: 3 days.

Treatment for maintenance of recurrence VVC*: once a week within 6 months.

*VVC recurrence is defined as symptoms VVC 4 times or more each year.

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.What do

do when overdose? Studies show that Clotrimazol places the vagina well and absorbed into the body very little. Oral studies show that if you accidentally take the single doses of clotrimazol, the drug is relatively well tolerated; And if taking high doses, the drug has a strong vomiting effect, helping to remove the drug from the body. If suspected of overdose, you need to report to the doctor immediately.

In an emergency, call the 115 emergency center immediately or go to the nearest local health station.

What to do when forgetting 1 dose?

Side Effects

Large -scale treatment experience and clinical trials show that Clotrimazol vaginal tablets are well tolerated.

Unwanted effects are common when using Clotrimazol vagina, including: vaginal irritation. Burns/pain and vaginal back.

In clinical trials using 200 mg of vagina to place the vagina 200 mg of clotrimazol, 24/832 patients (6.3%) experience adverse reactions. Most adverse reactions include itching and burning in place.

Rarely cases have to stop the drug. An allergic (hypotension, shortness of breath, urticaria): Pelvic pain. Vaginal bleeding, abdominal pain.

Notify the physician the unwanted effects when using the drug.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

Contraindicated

Candid V3 drug is contraindicated in the following cases:

Patients with clotrimazol hypersensitivity or Imidazol derivatives.

Children under 12 years old.

Be cautious when using

The drug is only used for vaginal placement.

Do not drink.

Leave the medicine out of the reach of children.

If there is no good progress after 3 days of medication or if you do not see the symptoms of 7 days, you must ask your doctor because not all vaginal infections are caused by yeast.

Before or during the use of the drug, if the symptoms appear such as pain in the abdomen, fever, smelled vaginal secretion, a doctor should consult.

If symptoms reappear after 2 months, immediately report to the doctor.

Use drugs during pregnancy or pregnancy only when prescribed by a doctor.

Do not use drugs for girls below 16 years old, unless the doctor is prescribed.

Stop using medication if there is a skin or irritation.

In case of missing medication. Need to notify the doctor immediately.

Stop the drug immediately and see the doctor if the vaginal bleeding is abnormal.

The effect of the drug on driving and operating machinery

Candid V3 drug does not affect or negligible on the ability to drive and operate machinery.

Use drugs for women during pregnancy and lactation

Pregnant women:

Clotrimazol vaginal tablets are used safely for women in pregnancy for the second and third but not yet evaluated in the first 3 months of pregnant women. This drug is only used for pregnant women in the first 3 months when prescribed by a doctor.

breastfeeding women:

It is not known whether Clotrimazol to put the vagina into the breast milk or not. Clotrimazol should only be used for vaginal placenta for breastfeeding women when they are really necessary.

Drug interaction

There is no information on the interaction of the Candid of the vagina, because the drug is less absorbing, the interaction with the whole body is almost no.

Storage

Leave a cool place, avoid light, temperatures below 30⁰C.

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