Carbotrim 200mg Pharmedic medicine for infections (10 blisters x 8 tablets)

Dosage form Box of 10 blisters x 8 tablets
Specifications Sulfamethoxazole, trimethoprim
Ingredient Otitis media, sinusitis, urinary tract infections, genital infections, digestive disorders, pneumonia, poisoning

Ingredient

Composition information	Content
Sulfamethoxazole	200mg
Trimethoprim	40mg

Uses

Indications

Carbotrim 200 mg is indicated in the following cases:

Infections caused by sensitive bacteria.

Pharmacology

sulfamethoxazole has a wide antibacterial spectrum, acting on many gramy and yin -yang gas bacteria including: Staphylococcus, Streptococcus, Legionella Pneumophila, Neisseria Gonorrhoeea, Neisseria Meningitide, E. CO, E. CO, E. CO, E. CO, E. CO, E. CO, E. CO, E. CO, E. CO, CO, E. CO, CO, E. CO, E. CO, E. Salmonella, Shigella, Enerobacter, Proteus Mirabilis, Proteus Indol positive, Klebsiella, Haemophilus Influenzae ...

Anti -drug bacteria are: Enterococcus, Campylobacter and anaerobic bacteria.

Mechanism of action of the drug: Sulfamethoxazol has the same structure as Para Aminobenzoic acid (PABA). It competes with PABA thanks to high affinity with dihydropteroat synthetase (inhibiting phase I of bacterial folic acid synthesis).

sulfamethoxazole is a sulfamid in combination with trimethoprim is a synthetic antibiotic derivative of Pyrimidin. These two substances are often combined in the ratio of 1 trimethoprim and 5 sulfamethoxazol. This combination creates a reinforcement effect that increases the effectiveness of treatment and reduces drug resistance.

pharmacokinetic pharmacokinetics

absorption: Sulfamethoxazole absorbs well through the gastrointestinal tract, highly available, reaching the concentration of blood in approximately intravenously.

Distribution: The drug is widely distributed into tissues and body fluids

Metabolism: sulfamethoxazole metabolism in the liver.

Elimination: The excreted drug is mainly in the intact and metabolic form. Selling time for waste 9 - 11 hours in normal people and longer in patients with renal failure.

Before taking Carbotrim 200mg Pharmedic medicine for infections (10 blisters x 8 tablets)

How to use

use by oral.

Dosage

Adults: 2 capsules each, 3-4 times/day.

Children 5 - 15 years old: 1-2 capsules each time, 2 times/day.

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.

What to do when using overdose?

How to handle: If any overdose appears when taking the drug, transfer to the nearest medical center for timely treatment assistance.

What to do when forgetting a dose? However, if close to the next dose, skip the forgotten dose and take the next dose at the time as planned. Do not drink twice as prescribed.

Side Effects

When using Carbotrim, you may experience unwanted effects (ADR).

Common, ADR> 1/100

Gastrointestinal: Nausea, vomiting, diarrhea, tongue inflammation.

Systemic: commonly fever, rarer, anaphylactic reaction, serum disease.

Skin: urticaria, itching, rare itchy has Lyell syndrome, Stevens - Johnson syndrome, diverse erythema, angioedema, light sensitivity.

Blood: acidic leukemia, neutropenia, hemorrhage, huge red blood cell anemia, hemolytic anemia, thrombocytopenia, reduced hemorrhage, hyperkalemia, hypoglycemia.

Genital - Urology: renal failure, interstitial nephritis, kidney stones.

Instructions on how to handle ADR

When experiencing side effects of the drug, it is necessary to stop using and notify the doctor or go to the nearest medical facility for timely treatment.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

Contraindicated

Carbotrim 200mg drug is contraindicated in the following cases:

Patients with huge red blood cell anemia.

Patients with severe hepatitis.

Be cautious when using

The drug can cause impaired renal function, in elderly patients can cause folic acid deficiency when taking long -term drugs, in addition the drug can cause dehydration, malnutrition.

The ability to drive and operate machinery

The drug does not affect the ability to drive and operate machinery.

Pregnancy

Because carbotrim can cause jaundice in children during the period of birth due to pushing bilirubin out of albumin, should only use the drug when it is really necessary, if you have to use medicine, use more folic acid.

Breastfeeding period

Because babies are very sensitive to the toxic effect of carbotrim, pregnant women do not use medication.

Medicinal interaction

Diuretics, especially Thiazid: Use simultaneously increases the risk of thrombocytopenia in the elderly.

Methotrexate: The drug can reduce the elimination, increase the effects of methotrexate.

pyrimethamine: simultaneous use of pyrimethamine 25 mg/week increases the risk of huge red blood cell anemia.

Phenytoin: The phenytoin metabolic inhibitor in the liver, which can increase the effect of phenytoin.

warfarin: The drug can extend prothrombin time in people who are using warfarin.

Storage

Store in a dry place, avoid moisture and light, temperature below 30ºC.

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Disclaimer

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