Cefatam 750mg pymepharco medicine for infections (10 blisters x 10 tablets)

Dosage form Box of 10 blisters x 10 tablets
Specifications Cephalexin
Ingredient Sore throat, otitis media, urinary tract infections, skin infections and soft tissue, meningitis caused by pneumococcal, chronic bronchitis

Ingredient

Composition information	Content
Cephalexin	750mg

Uses

Indications

Cefatam drugs are indicated in the treatment of sensitive bacteria infections.

Respiratory infections: Acute and chronic bronchitis, bronchodilatoma with superinfection. Preventing recurrence cases.

Pharmacokic

cephalexin is β-lactam antibiotic, which has bactericidal activity on many types of Gram (+) and Gram (-) bacteria. Cephalexin prevents the synthesis of bacterial cell walls. The mechanism of acidification of transpeptidase enzymes associated with the membrane, preventing the cross -linking of peptidoglycan needed for the stability and durability of the bacterial cell wall.

Antibacterial spectrum: Cephalexin works with staphylococcus aureus strains of penicillin -resistant penicillin. Cephalexin has an invitro effect on the following bacteria: Streptococcus beta blood -soluble, streptococcus pneuminiae, some E. coli, Proteus Mirabilis, Klebsiella spp ampicillin.

pharmacokinetic

absorption

Cephalexin stable with stomach acid. 90% are absorbed quickly and completely on the upper part of the stomach - intestinal tube after drinking. Cmax achieved after 60 - 90 minutes.

A blood concentration is about 9, 18 and 32 µg/ml 6 hours after taking the dose of 250mg, 500mg and 1g.

The peak concentration in serum decreases slightly when using cephalexin with food, although the total amount of drugs is constant.

Distribution

Wide distribution to the body of the body. High concentrations in all organizations, liver and kidneys. Cephalexin can pass the fetus and blood levels higher than 10% of the mother.

The drug is also found in bile, pus, aquatic fluid, breast milk and bones. Cerebrospinal fluid cannot be passed. 10 - 15% Cephalexin binds to plasma proteins.

metabolism and elimination

Selling time in plasma is about 30 - 72 minutes.

Cephalexin is not metabolized in the body.

70 - 90% excreted through urine in the form of unchanged after drinking 6 - 8 hours, due to glomerular filtration and excretion through the renal tubules, during this period, the peak concentration in the urine after the dose of 250mg - 500mg is 1000 µg/ml and 2200 µg/ml respectively.

Probenecid slows the excretion of the drug through urine. Effective treatment concentration can be found in bile and a small amount can be excreted through bile.

Before taking Cefatam 750mg pymepharco medicine for infections (10 blisters x 10 tablets)

How to use

cefatam hard capsules for oral orally.

Dosage

recommended dose:

Adults and children> 12 years old: 500mg x 3 times/day or 750mg x 2 times/day.

Preventing recurrent urinary tract infections: 125mg x 1 time/day (drinking in the evening).

Gonorrhea: Use a single dose 3g with 1g probenecid for men or 2g with 0.5g of Probenecid for women.

Children 5 - 12 years old: 250mg x 3 times/day or 750mg x 1 time/day.

Children 1- 5 years old: 125mg x 3 times/day.

Dosage correction in patients with renal failure:

Creatinine clearance from 40 - 50ml/minute: Maximum dose 3g/day. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.

What to do when using overdose?

Overdose: Respiratory support patient, transmitting solution of electrolytes, using activated carbon to reduce the absorption of drugs through the gastrointestinal tract. Dialysis can reduce the concentration of cephalexin in the blood when used overdose.

In an emergency, call the 115 emergency center immediately or go to the nearest local health station.

What to do when forgetting 1 dose? However, if the time to relax with the next dose is too short, skip the dose and continue the calendar of the drug. Do not use double dose to compensate for missed dose.

Side Effects

When using Cefatam often has unwanted effects (ADR) such as:

There may be nausea, vomiting, rash, diarrhea, hyperburis like Eosin, increased liver transaminase. Rare symptoms such as headache, dizziness, indigestion, gastritis, abdominal pain, fake colitis, Stevens-Johnson syndrome, diverse roses, vaginitis, genital itching, hepatitis and jaundice.

Notice the unwanted physician when using the drug.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

Contraindicated

Cefatam drugs contraindicated in the following cases:

Not for patients with hypersensitivity to cephalexin or β-lactam antibiotics.

Be cautious when using

It is very careful to use for medication for patients in the following cases:

Like other broad -spectrum antibiotics, using long -term cephalexin can overdue unsatisfactory bacteria (for example: Candida, Enterococcus, Clostridium difficile), in this case, the drug should be stopped.

There has been a notice of fake colitis when using broad -spectrum antibiotics, so it is necessary to pay attention to the diagnosis of this disease in severe diarrhea during or after antibiotics.

Pregnant women.

Need to adjust the appropriate dose in patients with renal function.

Using drugs for women during pregnancy and lactation

cephalexin through placenta and breast milk but there is no evidence of harmful to the fetus.

Safety during pregnancy and lactation when using cephalexin in humans has not been determined. Hence only used when necessary.

The effect of the drug on the ability to drive and operate machinery

There is no document clearly stating the influence of the drug when driving and operating machinery. However, be careful because there has been a notice of central neurological symptoms such as dizziness, agitation and hallucinations, but has not completely proved the relationship with Cephalexin.

Medicinal interaction

Medicinal interaction may affect the activity of the drug or cause side effects.

Patients should notify the doctor or pharmacist a list of the drugs and functional foods you are using. Do not use or increase or decrease the dose of the drug without the guidance of a doctor.

Taking drugs in combination with probenecid will extend the excretion time of cephalexin and increase serum concentration.

Storage

Leave a cool place, avoid light, temperature below 30⁰C.

Other drugs

Disclaimer

Every effort has been made to ensure that the information provided by Drugslib.com is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Drugslib.com information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Drugslib.com does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Drugslib.com's drug information does not endorse drugs, diagnose patients or recommend therapy. Drugslib.com's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners.

The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Drugslib.com does not assume any responsibility for any aspect of healthcare administered with the aid of information Drugslib.com provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.