CEFDINIR 300 - HV USP Treatment of infection (2 blisters x 10 tablets)

Dosage form Box of 2 blisters x 10 tablets
Specifications Cefdinir
Ingredient Tonsillitis, acute pharyngitis, sinusitis, acute bronchitis, pneumonia

Ingredient

Composition information	Content
Cefdinir	300mg

Uses

Indications

cefdinir 300 is indicated for cases of mild to medium infections, caused by sensitive bacteria in the following cases:

Pneumonia with the community suffered from the factors of Haemophilus Influenzae, Moraxella Catatrhalis (including Beta-Lactamase), Streptococcus pneumoniae (sensitive strain with penicillin).

Exacerbivorce of chronic bronchitis is also caused by Haemophilus Influenzae, Moraxella Catatrhalis (including Beta-lactamase), Streptococcus pneumoniae (sensitive strain with penicillin).

Acute sinusitis caused by Haemophilus Influenzae, Moraxella Catatrhalis (including Beta-Lactamase) and Streptococcus pneumoniae (sensitive to penicillin);

throat inflammation/tonsillitis caused by streptococcus pyogenes.

Skin infections and skin structure: due to Staphylococcus aureus (including Beta-lactamase) and Streptococcus Pyogenes.

Acute otitis media caused by Haemophilus Influenzae, Moraxella Catatrhalis (including seminarians beta-lactamase), Streptococcus pneumoniae.

Pharmacy

The main pharmaceutical of Cefdinir 300 is Cefdinir, active on many types of gram -positive and gram -negative bacteria.

Antibacterial spectrum includes:

Gram-positive bacteria: Staphylococcus aureus, Staphylocus Apidermidis (including Beta-Lactamase but sensitive to methicillin), Streptococcus pneumoniae, Streptococcus pyogenes (sensitive to penicillin).

Gram -negative bacteria: Haemophilus Influenzae, Moraxella Catatrhalis, Escherichia Coli, Kensella Pneumoniae, Proteus Mirabilis, Neisseria Gonorrhoeae.

pharmacokinetics

absorption

The maximum concentration of cefdinir in plasma appears after 2 to 4 hours after drinking. Cefdinir concentration in plasma increases with dose but increases less at the dose from 300 mg (7 mg/kg) to the dose of 600 mg (14 mg/kg). CEFDINIR's predictable bioavailability is 21% after taking the dose of 300 mg.

Distribution

The average distribution of CEFDinir in adults is 0.35 1/kg (± 0.29), in children (from 6 months to 12 years old) is 0.67/kg (± 0.38). Cefdinir is attached to plasma proteins from 60% to 70% in adults and children; Concentration does not depend on concentration.

Metabolism and elimination

Cefdinir metabolizes negligible. Cefdinir is excreted mainly through the kidney with an average selling time of 1.7 hours. In healthy people with normal kidney function, the clearance of the kidney is 2.0 (+ 1.0) ml/min/kg and the clearance of the kidney after taking the drug is 11.6 (T6.0) after taking the dose of 300 mg.

The ratio of reabsorption drugs in the form of unchanged urine after taking a dose of 300 mg is 18.4%. Cefdinir clearance in patients with renal failure.

Before taking CEFDINIR 300 - HV USP Treatment of infection (2 blisters x 10 tablets)

How to use

Take the whole pill.

Should take the medicine immediately after meals and at least 2 hours before or after using antacids or iron -containing preparations.

Dosage

Dosage and medication time for each specific case as prescribed by the treating doctor.

The usual dose is as follows: The treatment time is from 5-10 days depending on the case, can be used once a day or divided 2 times/day.

Adults and children over 13 years old:

Use 300 mg 2 times/day or 600mg/1 time/day.

The total dose is 600mg for infections.

Patients with renal failure:

Adults with creatinine clearance

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.

What to do when overdose? Dialysis can eliminate cefdinir from the body, especially in the case of kidney failure.

What to do when forgetting 1 dose? However, if the time to relax with the next dose is too short, skip the dose and continue the calendar of the drug. Do not use double dose to compensate for missed dose.

Side Effects

When using CEFDinir 300, you may experience unwanted effects (ADR). Unwanted effects because Cefdinir is usually light, including:

Rarely: diarrhea, nausea, headache, abdominal pain, rash, vaginitis;

Very rare: indigestion, flatulence, vomiting, anorexia, constipation, unusual feces, weakness, dizziness, insomnia, itching, chicken sleep.

Notify the doctor with unwanted effects when using the drug.

Instructions on how to handle ADR

Can reduce the side effects of the drug by reducing the dose.

When experiencing side effects of the drug, it is necessary to stop using and notify the doctor or go to the nearest medical facility for timely treatment.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

Contraindicated

CEFDINIR 300 drug is contraindicated in the following cases:

Patients with antibiotic cephalosporin or any ingredients of the drug.

Contraindicated in people allergies to penicillin.

Precautions when used

as well as other broad antibiotics, long -term treatment with Cefdinir can cause resistance bacteria. Need to monitor patients closely, if there is a phenomenon of re -infection during treatment, it is necessary to change to other antibiotics appropriately.

Be careful when used for patients with a history of colitis.

The ability to drive and operate machinery

The drug has almost no effect on driving and operating machinery. However, there are also a few reports on the risk of dizziness, so the doctor may depend on the specific case that is recommended or not recommended for patients to use drugs when driving and operating machinery.

Pregnancy and lactation

Pregnancy

There is no specific research on pregnant and lactating women, only taking the drug when really necessary.

Breastfeeding period

There is no specific research on pregnant and lactating women, only taking the drug when really necessary.

Medicinal interaction

Medications neutralizing gastric acid containing aluminum or magnesium and iron -containing preparations that reduce Cefdinir absorption. If it is necessary to stop these drugs while being treated with cefdinir.

Probenecid: Like other beta-lactam antibiotics inhibit the excretion of the kidneys.

Storage

Leave a cool place, avoid light, temperature below 30⁰C.

To be out of reach of children.

Other drugs

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