CEFDINIR 300mg DHG medicine treats community pneumonia, chronic bronchitis (2 blisters x 10 tablets)

Dosage form Box of 2 blisters x 10 tablets
Specifications Cefdinir
Ingredient Tonsillitis, pharyngitis, otitis media, sinusitis, acute bronchitis

Ingredient

Composition information	Content
Cefdinir	300mg

Uses

Indications

CEFDINIR 300 drugs are indicated in the following cases:

Treatment of community pneumonia, acute bronchitis, acute sinusitis, sore throat, tonsillitis.

Treatment of folliculitis, inflammation around the nails, impetigo, abscess under the skin, vasculitis or lymph nodes.

Treatment of nephritis, pyelonephritis, cystitis. Cefdinir has a wide range of resistant to high -negative bacteria such as Haemophilus influenzae, Haemophilus parainfluenzae, Moraxella Catatrhalis and Gram -positive bacteria such as Staphylococcus aureus, Streptococcus pneumoniae (sensitive to penicilin), streptoccus) pyogenes.

cefdinir is not affected by beta - lactamase enzymes, especially good effect on Gram -positive bacteria such as: Staphylococcus sp., Streptococcus sp. The anti -methicilin staphylococci strains are resistant to cefdinir.

pharmacokinetics

After taking Cefdinir, the peak concentration in plasma is reached from 2 to 4 hours. Absolute bioavailability is about 25% when used in the form of oral fluid.

In children from 6 months to 12 years old, taking the only dose of 7mg/kg Cefdinir in the form of a chaos, the peak concentration in plasma is 2.2 hours after use. When used in single dose 14mg/kg for these patients, the peak concentration of plasma is 1.8 hours after drinking.

Simultaneous use of CEFDinir in the form of oral fluid with high -fat meals reduces the peak concentration in plasma and AUC of the drug, equivalent to 44% and 33%. There is no evidence that CEFDinir accumulates in plasma after taking multiple doses in patients with normal kidney function with oral doses 2 times/day.

After drinking, Cefdinir is distributed into the middle ear fluid, tonsils, sinus tissue, bronchial and lung mucosa ... at different concentrations in plasma. In patients with acute otitis media due to bacteria when taking 7mg or 14mg/kg, the average concentration of the drug in the middle ear is 3 hours after drinking. CEFDINIR's cohesion ratio is 60 - 70%, this cohesion is independent of the concentration of the drug.

Cefdinir metabolizes negligible. The drug is excreted mainly in the kidneys. In adults with normal kidney function, the average selling time in the plasma of Cefdinir is 1.7 - 1.8 hours. Cefdinir's clearance in patients with impaired renal function. In patients with creatinine clearance of 30 - 60ml/ min, peak plasma concentrations and half -plasma semi -discharged time increased by 2 times and AUC tripled.

In patients with creatinine clearance below 30ml/min, the peak concentration in plasma increased by 2 times but the semi -waste time in plasma and AUC increased by 5-6 times corresponding. Cefdinir is removed from the body through the hemorrhage. About 63% of the drug is removed from the body for 4 hours according to the fertilizer line. CEFDINIR's waste sale time in patients with severe renal failure decreases from 16 to 3.2 hours.

Before taking CEFDINIR 300mg DHG medicine treats community pneumonia, chronic bronchitis (2 blisters x 10 tablets)

How to use

Take oral use. Treatment period 5 - 10 days.

Dosage

Adults and children over 12 years old

Use 300mg x 2 times/day.

CLCR

Use 300mg x 1 time/day.

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.

What to do when overdose?

Overdose treatment is mainly symptomatic treatment and drugs from the body. Hematopathy can be carried out to prevent the drug from the blood.

What to do when you forget a dose? However, if close to the next dose, skip the forgotten dose and take the next dose at the time as planned. Note that it should not be used double the prescribed dose.

Side Effects

When using CEFDinir 300, you may experience unwanted effects.

Rare (ADR

Nausea, vomiting, abdominal pain, anorexia, constipation.

Headache, dizziness.

Fungal stomatitis, fungal infection.

Lack of vitamin K, vitamin B.

leukopenia.

Hyper enzyme, bun (Blood Urea Nitrogen - Urea nitrogen index).

Instructions on how to handle ADR

When experiencing side effects of the drug, it is necessary to stop using and notify the doctor or go to the nearest medical facility for timely treatment.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

Contraindicated

Haginir 300 drugs against in the following cases:

Hypersensitivity to drug ingredients or cephalosporin groups.

Caution when using

Personal history or family allergic: urticaria, rash, bronchial asthma.

Severe kidney failure.

History of colitis.

Children under 6 months old.

The ability to drive and operate machinery

Caution when driving and operating machinery.

Pregnancy

There is no complete evidence of the ability of the drug for pregnant women.

Breastfeeding period

Do not detect cefdinir in breast milk after taking a single dose 600mg.

Be cautious when taking medication for pregnant and lactating women.

Medicinal interaction

should take at least 2 hours after taking antacids or iron preparations because of reducing bioavailability when shared.

Probenecid inhibits cefdinir excretion.

Storage

In a dry place, the temperature does not exceed 30 ° C, avoiding light.

Other drugs

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