Cefixim 200mg medicine Vidipha treat infections (1 blister x 10 tablets)

Dosage form Box of 1 blister x 10 tablets
Specifications Cefixim
Ingredient Tonsillitis, pharyngitis, otitis media, cervicitis, urinary tract infections, urethritis, acute bronchitis, gonorrhea, chronic bronchitis

Ingredient

Composition information	Content
Cefixim	200mg

Uses

Indications

Cefixim Vidipha 200 mg drugs are indicated in the following cases:

Inhabited urinary tract infections due to sensitive strains of E.coli or Proteus Mirabilis and some cases of non-complicated urinary tract infections caused by other gram-tam bacillus such as Citrobacter spp, Enterobacter spp., Klebsiella spp., Proteus spp.

Some cases of nephritis - pyelonephritis and urinary tract infections have complications caused by sensitive enerobacteriaceae, but the treatment results are worse than in case of unemployed urinary tract infections.

Acute otitis media caused by Haemophilus Influenzae (including beta-lactamase strains), Moraxella Catatrhalis (including beta-lactamase strains), Streptococcus pyogenes.

Sore throat and tonsils due to streptococcus pyogenes.

Acute and chronic bronchitis caused by Streptococcus Pneumoniae or Haemophilus Influenzae or Moraxella Catarrhalis.

Mild to moderate pneumonia, including the pneumonia sufficient in the community.

The drug is also used to treat gonorrhea without complications caused by Neisseria gonorrhoeae (including beta-lactamase strains); typhoid disease caused by salmonellatyphi (including multi -resistant strains); Sensitive shigella dysentery (including ampicillin resistant strains).

Pharmacy

cefixim inhibits the synthesis of bacterial cell walls by linking to one or more penicillin bonding proteins (PBP); Therefore, inhibiting the final transpeptide step of peptidoglycan synthesis in bacterial cell walls, thus inhibits biosynthesis of cell walls. Finally, bacteria are solved due to the continuous activity of self -resolved enzymes into cells (Autolysin and Murein Hydrolase) while the process of assembling cells into cells is arrested.

pharmacokinetic pharmacokinetics

Distribution: widely throughout the body and achieving treatment concentrations in most tissues and fluid fluids, including fluid, pericardium, pleura, and peritoneal; bile, sputum and urine; Bones, heart muscle, gallbladder, leather and soft tissue. Protein bond: 65%.

Elimination: Excretion in urine 50% of the absorption dose in the form of active drugs, through feces (10%). Selling time: Normal kidney function: 3 to 4 hours; Average decline (CrCl 20 to 40 ml/minute): 6.4 hours; Renal failure: up to 11.5 hours.

Before taking Cefixim 200mg medicine Vidipha treat infections (1 blister x 10 tablets)

How to use

Cefixim VIDIPHA 200 mg medicine for oral. Should take medicine after eating.

Dosage

Adults

Common doses used in adults 200 mg - 400 mg/day can be used once or divided into 2 times 12 hours apart.

To treat uncomplicated gonorrhea caused by Neisseria Gonorrhoeae (including beta-lactamase strains): Taking a dose of 400 mg (a single dose, more combined with an effective antibiotic for Chlamydia due to being infected at the same time).

For adults with spreading gonorrhea, the beginning of treatment with ceftriaxon injection, cefotaxim, ceftizoxim or spectinomycin and after the disease begins to improve, continue treatment as starting within 24-48 hours, then change to CEFIXIM drink, dose 400 mg/time, drink 2 times/day and for a minimum of 1 week.

When kidney failure needs to adjust the dose accordingly.

Children

Children over 12 years old or weighing over 50 kg: taking doses like adults.

To treat uncomplicated gonorrhea due to Neisseria gonorrhoeae for 8 -year -old children or older with weight equal to or over 45 kg: taking a dose of 400 mg (a single dose), combined with an effective antibiotic for chlamydia due to being likely to be infected at the same time.

Dosage for kidney failure: No dose adjustment for patients with creatinine clearance> 60 ml/min. For patients with creatinine clearance

Treatment time: Depending on the type of infection, it should be extended for 48-72 hours after the symptoms of infections have gone. The usual treatment time for uncomplicated urinary tract infections and upper respiratory tract infections is from 5-10 days (if due to streptococcus group A, Beta hemolysis must be treated for at least 10 days to prevent heart rheumatism or glomerulonephritis), lower respiratory tract infections and media: 10-14 days.

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.

What to do when using overdose?

What to do when you forget a dose? However, if close to the next dose, skip the forgotten dose and take the next dose at the time as planned. Note that it should not be used double the prescribed dose.

Side Effects

When using Cefixim Vidipha 200 mg, you may experience unwanted effects (ADR).

Common, ADR> 1/100

Digestive: diarrhea, abdominal pain, nausea, indigestion, flatulence, loose stool.

Uncommon, 1/1000

Systemic: Anaphylaxis, anaphylaxis, angioedema, dizziness, drug fever, face edema, fever, convulsions, Stevens-Johnson syndrome.

digestive: vomiting, fake colitis. skin: Poisoned epidermal necrosis, urticaria, diverse erythema, candidiasis. Blood: Nothing hypernagus, leukopenia, neutropenia, thrombocytopenia, long prothrombin time. liver: increased serum transaminase, hepatitis, increased blood bilirubin, jaundice. kidney: Acute renal failure.

Instructions on how to handle ADR

When experiencing side effects of the drug, it is necessary to stop using and notify the doctor or go to the nearest medical facility for timely treatment.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

Contraindicated

Cefixim VIDIPHA 200 mg drug is contraindicated in the following cases:

Patients with a history of hypersensitivity to Cefixim or with other cephalosporin antibiotics.

People with a history of anaphylaxis due to penicillin or allergies to other ingredients of drug products.

Precautions when using

Careful when using Cefixim in people with a history of gastrointestinal diseases and colitis, especially when prolonged use.

Dosage or number of drugs should be reduced in people with kidney failure.

For children under 6 months of age, so far there is no data on safety and effectiveness.

For the elderly: no dose adjustment, unless there is impaired renal function (creatinine clearance

The ability to drive and operate machinery

Because the drug can cause dizziness so be careful when using the drug for the driver and operating machinery.

Pregnancy

There is no complete research on pregnant women, when studying in animals, there has not been any effect on the fetus. Therefore, only use the drug when really necessary. Risk of pregnancy according to FDA: level b.

Breastfeeding period

Currently, it has not been confirmed for sure if Cefixim is distributed into milk or not. Therefore, it is advisable to use medication for women who are cautious, can temporarily suspend breastfeeding during medication.

Drug interaction

Probenecid increases the peak and AUC concentration of Cefixim, reduces the clearance of the kidney and the distribution of the drug.

anticoagulants like warfarin when used with cefixim increase prothrombin time and can enhance anticoagulant effects.

Storage

In a dry place, temperatures below 30 ° C.

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