Cefpodoxim 200mg TV.PHARM Treatment of infection (3 blisters x 10 tablets)

Dosage form Box of 3 blisters x 10 tablets
Specifications Cefpodoxime
Ingredient Sinusitis, skin infections and soft tissue, acute bronchitis, chronic bronchitis, pneumonia

Ingredient

Composition information	Content
Cefpodoxime	200mg

Uses

Indications

cefpodoxim is used in oral form to treat sensitive bacteria infections.

Treatment of mild to medium diseases in the lower respiratory tract, including acute pneumonia is acquired in the community due to streptococcus pneumoniae or haemophilus influenzae sensitive (including semi -born Beta - lactamase) and the acute phase of sensitive S. Pneumoniae strains and caused by H. Influenzae or MoraMae (Branhamella, formerly called Neisseria) CatVrhalis, did not produce beta - lactamase.

Treatment of mild and medium infections in the upper respiratory tract (for example, sore throat, tonsillitis) caused by sensitive streptococcus pyogenes strains. Acute otitis media caused by S. Pneumoniae strains, H. Influenzae sensitive (including the strains producing beta - lactamase) or B. CatVrhalis.

Treatment of mild and medium -sized urinary tract infections, unprovenes (cystitis) caused by E. coli strains, Klebsiella Pneumoniae, Proteus Mirabilis, or Staphylococcus Saprophyticus.

Treatment of acute gonorrhea, inconstatable, endothelial or anus - rectum of women and gonorrhea in the urethra of women and men, due to strains with or not producing penicilinase of Neisseria Gonorrheaa (a single dose of 200mg).

Treatment of mild infections to fit skin complications and skin organizations caused by staphylococcus aureus created or not producing penicillinase and sensitive streptococcus pyogenes strains.

Pharmacokology

cefpodoxim is the 3rd generation Cephalosporin antibiotic. Cefpodoxim has wide antibacterial spectrum for many Gram -positive and gram -negative bacteria. Cefpodoxim is stable when there is the presence of beta-lactamase enzymes. Therefore, many bacteria are resistant to penicillin and several antibiotics of cephalosporin groups caused by beta-lactamase bacteria, which can be sensitive to cefpodoxim. Cefpodoxim is inactivated by some broad spectrum beta-lactamase.

Cefpodoxim's bactericidal properties due to inhibition of bacterial cell wall synthesis. In principle, Cefpodoxim has a activity for Gram -positive bridge such as streptococcus pneumoniae), streptococcus streptococcus (streptococcus) group A, B, C, G and with staphylococcus aureus, S. Epidmidis staphylococcus anus or not producing beta - lactamase.

However, the drug has no anti -staphylococcus staphylococci -resistant staph - penicillin due to changes in penicillin -mounted proteins (the resistance of methicilin staphylococcus methicilin MRSA). This MRSA antibiotic resistance is growing in Vietnam.

Cefpodoxim also works for Gram -negative bacteria, Gram -positive and gram -negative bacilli. The drug has anti -gram -negative anti -bacteria such as E. Coli, Klebsiella, Proteus Mirabilis and Citrobacter.

Staphylococcus a staphylococcus of methicilin, Staphylococcus Saprophyticus, Enterococcus, Pseudomonas Aeruginosa, Pseudomonas spp Full cephalosporin.

pharmacokinetics

cefpodoxim Proxetil is absorbed through the gastrointestinal tract and is metabolized by non -specific esterase, maybe in the intestinal wall, the cefpodoxim metabolic wall works.

Birth of Cefpodoxim is about 50%. This bioavailability increases when using Cefpodoxim with food. The half -life of Cefpodoxim is 2.1 - 2.8 hours for patients with normal kidney function. Half of the serum increases to 3.5 - 9.8 hours in people with kidney disabled. About 40% Cefpodoxim binds to plasma proteins.

The drug is eliminated in the form of non -change through the filter of the glomerular and excretion of the renal tubules. About 29 - 38% of the dose is eliminated within 12 hours in adults with normal kidney function.

Before taking Cefpodoxim 200mg TV.PHARM Treatment of infection (3 blisters x 10 tablets)

How to use

cefpodoxim 200mg in the form of oral film tablets.

Dosage

Adults and children over 13 years old

Treatment of acute drama of chronic bronchitis or mild acute pneumonia to medium medium of the community, common dose: 200mg/time, every 12 hours, in 10 or 14 days, respectively.

For sore throat and/or tonsillitis mild or medium or mild or incomplete urinary tract infections: 100 mg every 12 hours, for 5-10 days or 7 days.

For skin infections and mild and medium -complicated skin organizations, the common dose is: 400 mg every 12 hours, for 7-14 days.

Treatment of unprocessed urethral gonorrhea in men, women and gonorrhea diseases and cervical endotheliality in women: taking a single dose of 200 mg of cefpodoxim, followed by oral doxycyclin treatment to prevent Chlamydia infection

Dosage for patients with renal impairment: It must be reduced depending on the degree of renal failure. For patients with creatinine clearance less than 30ml/min, and no blood separation, common dose, for each 24 hours apart. Patients are taking blood apart, taking the dose often 3 times/week.

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.What do

do when overdose? Symptoms due to overdose may include nausea, vomiting, epigastric pain and diarrhea.

Management: In case of severe poisoning reactions due to overdose, hemolysis or peritoneal fertilizer can help remove Cefpodoxim from the body, especially when the kidney function is impaired.

What to do when you forget a dose? However, if close to the next dose, skip the forgotten dose and take the next dose at the time as planned. Note that it should not be used double the prescribed dose.

Side Effects

When using Cefpodoxim 200mg, you may experience unwanted effects (ADR).

Common: Nausea, vomiting, diarrhea, abdominal pain, headache, rash, urticaria, itching.

Uncommon: reactions like serum with rash, fever and joint pain and anaphylactic reaction.

Skin: Diverse erythema.

Blood: Eosinemia, blood disorders.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

contraindicated

cefpodoxim 200mg contraindicated in the following cases:

Hypersensitivity to any ingredients of the drug.

Be cautious when using

Before starting treatment with cefpodoxim, a thorough investigation of the patient's allergic history with cephalosporin, penicillin or other drugs.

Need to use cautiously for people who are sensitive to penicillin, kidney and pregnant or nursing mothers.

The ability to drive and operate machinery

can occur dizzy and cautious when used for drivers and operating machinery.

Pregnancy and lactation

Pregnancy: Caution for pregnant women because there is no document about using Cefpodoxim during pregnancy.

Breastfeeding period: Use cautiously because Cefpodoxim is secreted in breast milk with low concentrations. Despite low concentrations, there are still 3 problems that will occur for breastfed children with cefpodoxim: Disorders of intestinal bacteria, directly acting to the child's body and bacterial culture results will be wrong, if antibiotic when fever.

Drug interaction

Cefpodoxim absorption is reduced when there is anti -acid, so avoid using cefpodoxim along with anti -acid.

Storage

Store in a dry place, the temperature does not exceed 30ºC, avoiding light.

Other drugs

Disclaimer

Every effort has been made to ensure that the information provided by Drugslib.com is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Drugslib.com information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Drugslib.com does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Drugslib.com's drug information does not endorse drugs, diagnose patients or recommend therapy. Drugslib.com's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners.

The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Drugslib.com does not assume any responsibility for any aspect of healthcare administered with the aid of information Drugslib.com provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.