Celecoxib 200mg Stella drugs treat symptoms of osteoarthritis, rheumatoid arthritis (6 blisters x 10 tablets)

Dosage form Celecoxib
Specifications Stella
Ingredient Vietnam

Ingredient

Composition information	Content
Celecoxib	200mg

Uses

Indications

Celecoxib 200 drugs are indicated in the following cases:

Treatment of symptoms of osteoarthritis (OA) and rheumatoid arthritis (out).

Pharmacokinus

No data.

pharmacokinetics

No data.

Before taking Celecoxib 200mg Stella drugs treat symptoms of osteoarthritis, rheumatoid arthritis (6 blisters x 10 tablets)

How to use

Celecoxib used by oral, can be used with food or not.

For patients with difficulty swallowing capsules, it is possible to put the amount of pills in the juice of apple smoothie, porridge, yogurt or crushed bananas to drink. At that time, the entire amount of drugs must be added to about a small teaspoon of apple smoothie, porridge, yogurt or crushed bananas at room temperature and must drink immediately with water. The amount of drug mixed with apple juice, porridge or yogurt is stable for about 6 hours when stored in the refrigerator (2 - 8oC/35 - 45OF). Do not be stored in the refrigerator amount mixed with crushed bananas and must be taken immediately.

Dosage

Adults

Symptomatic treatment in osteoarthritis (OA): Celecoxib's recommendations are 200 mg used for single or 100 mg, 2 times daily. everyday. Some patients may be better if they take a total dose of 400 mg daily. In the following days, the recommended dose is 200 mg 2 times daily when needed. In the following days, the recommended dose is 200 mg 2 times daily when needed.

Elderly people

Elderly patients weighing less than 50 kg, should start treating with the lowest recommended dose.

Weight ≥ 10 kg to ≤ 25 kg: 50 mg capsules, 2 times daily.

No dose adjustments for patients with mild liver failure (group A). Use Celecoxib at half a recommended dose for patients with arthritis or suffer from medium liver failure (group B).

Patients with renal failure

No dose adjustment for medium and mild renal impairment patients. There are no clinical studies in patients with severe renal impairment.

People with poor metabolism CYP2C9

Patients who know or suspect poor metabolism through CYP2C9 based on a history/experience with other substrates of CYP2C9 should be cautious when using Celecoxib. Start treatment with 1/2 of the lowest recommended dose.

Use in combination with fluconazole

should use Celecoxib with half recommended dose in patients who are being treated with fluconazole, a CYP2C9 inhibitor. Caution should be used when using Celecoxib with CYP2C9 inhibitors.

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.

What to do when overdose?

What to do when you forget 1 dose? However, if the time to relax with the next dose is too short, skip the dose and continue the calendar of the drug. Do not use double doses to compensate for missed dose.

Side Effects

When using Celecoxib may experience unwanted effects (ADR) such as:

Less:

Conjunctivitis;

chest pain.

Rare:

The illusion;

pneumonia, pneumonia;

gastrointestinal bleeding;

Notify the physician with unwanted effects when using the drug.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

contraindicated

Celecoxib drugs contraindicated in the following cases:

History of hypersensitivity to Celecoxib or any ingredient of the drug. Cycloxygenase-2 (COX-2) is different. Child-Pugh ≥ 10).

Be cautious when using

need to be very careful when taking the drug for patients in the following cases:

Heart effect

Risk of cardiovascular thrombosis: nonsteroidal anti -inflammatory drugs (NSAIDs), not aspirin, using systemic sugar, can increase the risk of cardiovascular thrombosis, including myocardial infarction and stroke, which can lead to death. Translation and edema: edema and fluids were observed on some patients using Celecoxib.

Effects on gastrointestinal tract

Most random reports on Celecoxib -related deaths occur in the elderly or weak patients.

Effects on the kidneys

Patients with the highest risk of kidney toxicity are those who fail kidney function, heart failure, liver failure and the elderly, need to carefully monitor these patients when treated with Celecoxib. First need to rehydration for patients and then start treatment with Celecoxib.

Progressive kidney disease

Need to closely monitor kidney function in patients with renal disease progressive treatment with Celecoxib.

Anaphylactic reaction

Anaphylactic reactions occur in patients using Celecoxib.

Serious skin reactions

Some serious reactions on the skin, can lead to death, including flaking dermatitis, Stevens-Johnson syndrome and poisoned epidermal necrosis.

Effects on the liver

Do not use Celecoxib in patients with severe liver failure, need to be cautious when using Celecoxib in medium liver failure patients (group B) and should start at half the recommended dose. When using Celecoxib.

Use with oral anticoagulants

There has been a report on serious bleeding in patients who are using Warfarin simultaneously or similar substances, including some deaths.

Teenagic spontaneous arthritis on the body

Be cautious when taking NSAID drugs including Celecoxib in patients with spontaneous arthritis of teenagers on the body, due to the risk of pervasive intravascular coagulation.

Overview

With anti -inflammatory effects, Celecoxib can fade diagnostic signs, such as fever symptoms in the diagnosis of infection.

CYP2D6 inhibition

Celecoxib is a medium level of CYP2D6 inhibitors. For drugs metabolized through CYP2D6, it is necessary to reduce the dose of these drugs when starting to use with Celecoxib or increase the dose of these drugs when stopping using Celecoxib.

excipients

Do not use this medication for patients with rare genetic problems galactose intolerance, total lactase enzyme deficiency or poorly absorbent glucose-galactose.

Reproduction

Women who are difficult to conceive or are treating infertility should consider stopping nsaids, including Celecoxib.

The effect of the drug on the ability to drive and operate machinery

Patients may be dizzy, dizzy or sleepy when using Celecoxib, should not control or operate machinery.

Use drugs for women during pregnancy and lactation

Pregnant women:

Celecoxib, as well as other prostaglandin synthesis inhibitors, can cause powerless uterine muscle and early aortic muscle, should avoid using Celecoxib in the third quarter of pregnancy.

Should only use Celecoxib during pregnancy if the potential benefits to the mother outperform the potential risk to the fetus.

Breastfeeding period:

Drug interaction

drug interactions can affect the activity of the drug or cause side effects.

Patients should notify the doctor or pharmacist a list of the drugs and functional foods you are using. Do not use or increase or decrease the dose of the drug without the guidance of a doctor.

Please see more information about drugs in the instructions for the use of drugs attached.

Storage

Leave a cool place, avoid light, temperatures below 30⁰C.

To be out of reach of children, read the instructions carefully before use.

Other drugs

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