Cerecozin 500mg stars supports improving memory (3 blisters x 10 tablets)
Dosage form Box of 3 blisters x 10 tablets
Specifications Citicoline
Ingredient Cerebral circulatory disorders, Parkinson, dementia due to brain vessels, Alzheimer, Trauma, anxiety
Ingredient
| Composition information | Content |
| Citicoline | 500mg |
Uses
indications
Celecozin drugs are indicated in the following cases:
citicolin is a pyrimidine -5 - nucleotide, a necessary precursor in the synthesis of lecithin (phosphatidylcholin) and other phospholipids. Citicolin is used to increase, maintain and restore cell membranes and nerve function in the event of ischemia, because citicolin increases the synthesis of phosphatidylcholine and other phospholipids.
Wide lesions due to stroke need to be repaired and regenerated otaxon and nerve synap, so it is necessary to create new cell membranes. The main mechanism that makes citicolin has the effect of treating stroke is thought to be due to the ability to synthesize phosphatidylcholin, which is the main component of the nerve cell membrane. Citicolin also increases the synthesis of acetylcholine, thus reducing and limiting the amount of nerve cell damage, restoring the sensitivity and function of the intracellular regulating enzymes, promoting the reabsorption in cerebral disease. In patients with memory loss due to age, citicolin reduces the process of damage.
Dynamic pharmacokinetics
citicolin is a water -soluble compound that is more than 90%. Citicolin is metabolized in the intestinal wall and liver. The by -products from external hydrolysis in the intestine are cholin and cytidin. After absorption, Choline and cytidin distributed the whole body, enters the circulatory system and is used in many biosynthetic lines, through the brain blood barrier to re -synthesize into citicolin in the brain.
Citicolin elimination is mainly through urinary tract and respiratory tract in 2 stages, shown at two peaks of plasma concentrations. The first peak in plasma fell rapidly then slowed down for the next 4 - 10 hours. In phase 2, the peak of concentration decreases rapidly after 24 hours, then the elimination rate is slower. The sale time of citicolin is 56 hours.
Oral citicolin increases the concentrations of cytidin and cholin within 6-8 hours. Used for 42 and 90 days increases the concentration of the brain of phosphatidylcholin, phosphatidylethanolamine and phosphatidylserin, are the three main phospholipids of the brain cell membrane. In the dose of 500 mg/day, the concentration of phosphatidylcholine increased by 25%, phosphatidylethanolamine increased by 17%and phosphatidylserine increased by 42%.
Before taking Cerecozin 500mg stars supports improving memory (3 blisters x 10 tablets)
How to use
Celecozin is oral medication.
Can take whole tablets with water or pills in a cup containing 10 - 15 ml of water, shake to completely scattered and drink, drink before meals.
Dosage
Loss of consciousness due to brain damage, head damage or brain surgery, brain anemia, memory problems of the elderly and stroke: take 1 tablet/time x 1-2 times/day.
Support improves thinking, learning and memory in Alzheimer patients, memory loss, head injury: Take 2 capsules/time/day, use for 2 consecutive weeks.
Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.What to do when overdose? In a short -term placebo, 12 healthy people use 600 mg and 1000 mg daily or placebo for 5 consecutive days. Airborne headache 24 users dose 600 mg, 5 users dose 1000 mg and 1 placebo users. There is no abnormalities in hematology, clinical biochemistry or neurological testing. There is no specific antidote, mainly supporting symptoms if overdose occurs.
What to do when you forget a dose? However, if close to the next dose, skip the forgotten dose and take the next dose at the time as planned. Note that it should not be used double the prescribed dose.
Side Effects
When using Celecozin, you may experience unwanted effects (ADR).
Common, ADR> 1/100
Uncommon, 1/1000 ≤ ADR
Rare, 1/10000 ≤ ADR
Liver: Abnormal liver function test.
Instructions on how to handle ADR
When experiencing side effects of the drug, it is necessary to stop using and notify the doctor or go to the nearest medical facility for timely treatment.
Warnings
Before using the drug you need to read the instructions carefully and refer to the information below.
Contraindicated
Celecozin drugs contraindicated in the following cases:
Be cautious when using
In acute and emergency cases, citicolin should be used with intracranial pressure reducing drugs and stable treatment such as cooling down. If you continue to have a cerebral hemorrhage, avoid high doses of citicolin (> 500 mg) because it can increase blood flow in the brain. In this case, low -dose citicolin may be used (100 - 500 mg, 2-3 times/day).
Should be cautious in patients with sensitivity. For patients with consciousness disorders in the acute stage of anemia, it is recommended to use citicolin injections for 2 weeks after a stroke.
In the composition of cerecozin contains aspartam and manitol. Aspartam is hydrolyzed in the gastrointestinal tract after drinking. One of the hydrolysis products is phenylalanin. Precautions when used for patients with phenylceton, a rare genetic disorder in which phenylalanin is accumulated because the body cannot be eliminated. Manitol may have a light laxative effect.
The ability to drive and operate machinery
This drug can cause headaches, dizziness, convulsions. So be cautious when driving or operating machinery.
Pregnancy
Do not use drugs for pregnant women.
Demonstrate period
Do not take medicine for nursing women.
Drug interaction
used in combination with Levodopa, Citicolin can increase the side effects of Levodopa.
Avoid use with meclophenoxate (Centrofenoxin) because citicolin can increase the toxicity of meclophenoxate (Centrofenoxin).
The correspondence of the drug
due to the absence of studies on the cavalry of the drug, not mixing this drug with other drugs.
Storage
In a dry, cool place, avoid light, the temperature does not exceed 30 ° C.
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