Cerefort 800mg Unipharma treat dizziness, memory impairment (3 blisters x 10 tablets)

Dosage form Box of 3 blisters x 10 tablets
Specifications Piracetam
Ingredient Ischemia, muscle vibration, cognitive impairment, headache, dizziness

Ingredient

Composition information	Content
Piracetam	800mg

Uses

Indications

Cerefort drugs are indicated in the following cases:

Treatment of dizziness symptoms. 927 patients with acute ischemic stroke shows progress on behavior after 12 weeks of treatment, especially in patients who initially have severe neurological symptoms that are taken within the first 7 hours after the stroke). Attention should be paid to the age and severity of the first variable is the most important factor to prioritize the ability to survive the stroke of anemia stroke. Support for reading. Its action mechanism.

Even the definition of the Nootropic cave is still vague. In general, the main effects of the drugs are called Hung Tri such as: Piracetam, Oxiracetaxi, Aniracetam, Etiracetam, Pramiracetam, Tenilsetam, Suloctidil, Tamitinol) is to improve learning and memory ability.

Many of these substances are considered to have a stronger effect on piracetam in terms of learning and memory. It is thought that in normal people and in people with impaired function, Piracetam works directly to the brain to increase the activity of the brain area (the brain area is involved in the mechanism of awareness, learning, memory, alertness and consciousness).

Piracetam acts on some neurotransmitters such as acetylcholin, noradrenalin, dopamin ... This can explain the positive effect of the drug on learning and improve the ability to perform memory tests.

The drug can change neurotransmitter and contribute to improving the metabolic environment so that the nerve cells work well. On experiments, Piracetam has a protective effect against metabolic disorders due to ischemic by increasing brain resistance to oxygen deficiency. Piracetam increases the mobilization and use of glucose without depending on the supply of oxygen, facilitates the pentose path and maintains energy synthesis in the brain.

Piracetam enhances the recovery rate after damage due to lack of oxygen by increasing the rotation of inorganic phosphate and reducing glucose and lactic acid accumulation. Under normal conditions as well as without oxygen, Piracetam is found to increase the amount of ATP in the brain due to increased ADP conversion to ATP; This may be a mechanism to explain some useful effects of the drug.

The impact on acetylcholin transmission (increasing the release of acetylcholin) may also contribute to the mechanism of action of the drug. The drug also works to increase the release of dopamine and this may have a good effect on the formation of memory. The drug has no effect on sleep, sedation, resuscitation, analgesic, nervous or neuron and no effect of GABA.

Piracetam reduces the ability to converge platelet and in case of abnormal erythrocytes, the drug can cause red blood cells to restore deformation and ability to pass through capillaries. The drug has anti -vibration effect.

pharmacokinetics

Piracetam used by oral is absorbed quickly and completely in the digestive tract. Biological use is nearly 100%. Peak of plasma peaks (40 - 60 micrograms/ml) appears after 30 minutes after taking a dose of 2 g.

The peak concentration in the cerebrospinal fluid is achieved after taking the drug 2 - 8 hours. Absorption of drugs does not change when long -term treatment. Piracetam's distribution volume is about 0.6 liters/kg.

Piracetam absorbed into all tissues and can be through the bloody barrier, placenta and even the diaphragm in the kidney. The drug has high concentrations in the cerebral cortex, frontal lobe, top lobe and occipital lobes, cerebellar and base nuclei. Half life in plasma is 4-5 hours, half a life in cerebrospinal fluid about 6 - 8 hours.

Piracetam is not attached to plasma proteins and is excreted through the kidneys in the form of intact. Piracetam clearance coefficient of the kidney in normal people is 86 ml/min. 30 hours after drinking, more than 95% of the drug is discharged in urine. If there is a kidney failure, half a lifetime elimination increases: In patients with complete renal failure and not recovering, this time is 48 - 50 hours.

Before taking Cerefort 800mg Unipharma treat dizziness, memory impairment (3 blisters x 10 tablets)

How to use

Take oral use.

Dosage

The usual dose is 30 - 160mg/kg/day depending on the indications, divided evenly drink twice a day or 3-4 times. In severe cases, the dose can be increased to 12g/day and using intravenous piracetam.

Long -term treatment of physical mental syndrome in the elderly:

1,2 - 2.4g/day, depending on the case. The dose may be high to 4.8g/day in the first weeks

Alcoholic treatment:

12g/day during the first time of alcohol. Maintenance treatment: 2.4g/day.

Cognitive decline after brain injury: (with dizziness or no):

The initial dose is 9 - 12g/day. The maintenance dose is 2.4g/day, drinking at least 3 weeks.

sickle cell anemia:

160 mg/kg/day, divided equally into 4 times.

Treatment of muscle vibration:

dose of 7.2 g/day, divided into 2-3 times. Depending on the response, every 3-4 days, an increase of 4.8g daily to a maximum dose of 20g/day. After reaching the optimal dose of Piracetam, it is advisable to find a way to reduce the dose of the attached drugs.

What to do when overdose? There is no need for special measures when missing overdose.

What to do when forgetting 1 dose? However, if the time to relax with the next dose is too short, skip the dose and continue the calendar of the drug. Do not use double dose to compensate for missed dose.

Side Effects

When using Cerefort, you may experience unwanted effects (ADR).

Common, ADR> 1/100

Body: fatigue

Body: Dizziness.

Can reduce the side effects of the drug by reducing the dose.

When experiencing side effects of the drug, it is necessary to stop using and notify the doctor or go to the nearest medical facility for timely treatment.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

Contraindicated

Cerefort drugs contraindicated in the following cases:

Patients with severe renal impairment (Creatinine clearance coefficient below 20 ml/minute).

People with Huntington disease.

Caution when used

Because Piracetam is discharged through the kidneys, the half -life of the drug increases related to the degree of renal failure and creatinine clearance. It is necessary to be very cautious when taking the drug for patients with renal failure. Need to monitor kidney function in these patients and elderly patients.

When the clearing coefficient of creatinine is below 60 ml/minute or when the serum creatinine is over 1.25 mg/100 ml, the dose adjustment must be adjusted:

Creatinine clearance coefficient is 60 - 40 ml/min, serum creatinine is 1.25 - 1.7 mg/100 ml (half -life of Piracetam is twice as long): Only 1/2 normal dose should be used. hour): Use 1/4 of normal dose.

The ability to drive and operate machinery

The drug can affect the ability to drive or operate machinery so be careful when used.

Pregnancy

Piracetam can be through the placenta. Do not use this medication for pregnant people.

Breastfeeding period

Medicinal interaction

can still continue the classic method of alcoholic (vitamins and sedatives) in the case of a person with vitamin deficiency or strong agitation.

There has been a case of interaction between piracetam and thyroid essence when used simultaneously: confusion, stimulation and sleep disorders.

In a patient, prothrombin time has been stabilized by warfarin when using piracetam.

Storage

Store at temperatures below 30 ° C. Stay out of reach of children.

Expiry date: 3 years from the date of manufacture.

Not used when the drug is overdue on the label.

Other drugs

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