Chewing Kiddiecal Catalent supplements calcium and vitamin D (30 tablets)

Calcium is essential for children's bone and muscle development, to form teeth. Calcium deficiency can lead to osteoporosis in the future life. Contains vitamins K1 and D3 to increase the supply and absorption of calcium. Support maintaining or improving health in general.

Calcium is essential for neurotransmission, muscle contraction, vasodilation, vasodilation, excretion of glands, capillary permeability and cell membranes, enzyme reactions, respiration, kidney function and blood clotting. Calcium involves releasing and reserving hormones and neurotransmitters, absorption and cohesion of amino acids, the absorption of cyanocobalamin and gastrin excretion. Calcium in bone is a source of calcium reserves that can be mobilized to maintain extracellular calcium.

Phosphorus plays a decisive role in energy storage, metabolism, the use of B - Complex vitamins, the exact function of the nerve and muscle cells and maintain the function of calcium. Phosphorus plays a key role for teeth and bone formation. Healthy bones and soft tissues need calcium and phosphorus to increase and develop throughout life.

The main function of vitamin D is to adjust the concentration of phosphorus and plasma calcium. Vitamin D enhances the effectiveness of the intestinal absorption of calcium (mainly in the duodenum and nodes) and of phosphorus (especially in the nodes and ileum). Because vitamin D is very important for calcium lipstick and bone health, should be used to help prevent osteoporosis.

Vitamin K is an enzyme for the synthesis of the liver of coagulation factors II (prothrombin), VII (Proconvertin), LX (Christmas element or plasma thromboplastin component), and X (Stuart - Prower), and C protein C and S in the liver. Vitamin K is also associated with carboxylation of gamma - carboxyglutamate (GLA) proteins that make it easy to connect blood coagulation factors.

Vitamin K is a co -factor for carboxylation of bone proteins, including hydroxyapatite. Osteocalcin is in the process of carboxylation (Ucoc, also known as free osteocalcin) that has a weaker affinity for hydroxyapatite and therefore will be weaker.

Vitamin K can also reduce bone destruction by reducing the synthesis of prostaglandin E2 in bone cancellation cells, and by impact on calcium balance, and the production of Interleukin 6 in the bone. The supplementation of vitamin K increases the amount of osteocalcin has been carved in post -menopausal women. Atherosclerosis is associated with low serum K vitamin K. Vitamin K supplements can protect against atherosclerosis.

pharmacokinetics

The intestinal absorption in the intestine is inversely proportional to the amount of calcium eaten, so when a low -calcium diet will lead to increased absorption, partly due to the effects of vitamin D. significantly reduced level of absorption with age. Diseases with fat, diarrhea, and chronic absorption in the intestine also increase calcium in the stool.

After use, the amount of calcium ions discharged in the urine is the difference of the amount filtered in the glomerular and the amount of reabsorption. The reabsorption in the renal tubules is very effective because more than 98% of the calcium ionic ions are filtered through the glomerular reabsorption into the bloodstream. The reabsorption efficiency is the main regulatory regulatory by the hormone and is also affected by the purification of Na+, the presence of non -reabsorbed anions and diuretic.

Diuretics act at the upward branch of the Henle straps increases calciumuria. In contrast, only thiazid diuretics are not attached to the excretion of Na+ and Ca2+, resulting in reduction of calcium urine. Armor hormone always regulates blood calcium ionic concentration by acting on the renal tubules. Calcium is only affected by calcium diet in normal people. A significant amount of calcium is deducted from milk during breastfeeding, a part of sweat and stool.

When taken, vitamin D is absorbed in the ileum of the small intestine with other fats in food with the help of bile. Sell ​​waste time during the circulation of vitamin D from 1-2 days.

Vitamin K is absorbed in the ileum and the rosary of the small intestine. The absorption level of vitamin K in food, supplements and is injected, fluctuating between 10-80% (average is 50%), depending on the fats in the accompanying food and the effectiveness of bile acid. After absorption, (like other lipids) 90% of the absorbed vitamin K is transported on micro -micro -micro -micro -body of the absorbed vitamin K transported on the microscope, then VLDL and LDL to the liver for reserve.

50% of the liver's vitamin K in the form of vitamin K1. The amount of vitamin K reserved in the body will drop very quickly when vitamin K supplementation is not enough. The sale time of vitamin K is 1.5 - 3 hours. After metabolism, vitamin K (and its oxidized metabolites) are associated with glucuronic acid and excreted in bile (partial) and urine (mainly).

Be cautious when using

The drug can only help if vitamins from the daily food source are not enough.

If symptoms do not help please consult a doctor.

To be out of reach of children.

The ability to drive and operate machinery

can be used when driving and operating machinery.

Pregnancy

Used for pregnant women.

Breastfeeding period

Used for breastfeeding women.

Medicinal interaction

bisphosphonates (Alendronate, Etidronate, ibandronate, RiseDronate and Tiludronate): Calcium supplementation reduces bisphosphonate absorption. Patients should take bisphosphonate 30 minutes before taking calcium, but it is best to take the drug in 2 different sessions of the day.

Calcium increases the toxicity of digitalis glycosides for the heart because of increased blood calcium levels will increase the inhibitory effect of Na +- K +- Atpase of the cardiac glycosides. The doctor should consult with the appropriate dose of calcium as well as check blood calcium levels if necessary.

Calcium should be adjusted if used with digoxin because it is likely to affect blood calcium concentration.

Calcium reduces the absorption of quinolon or tetracyclin antibiotics, so when using calcium with levothyroxine or some groups of quinolon or tetracycline, should consult with a doctor or pharmacist before use.

No concurrent treatment with cholestyramin or colestipol, phenobarbital or phenytoin, corticosteroids, as they can interfere with the absorption of vitamin D or reduce the effect of vitamin D. simultaneous treatment of vitamin D with thiazid diuretic in patients with parathyroidism can increase blood calcium.