Chewing Montemax 5mg ATCO treat chronic asthma (1 blister x 14 tablets)

Dosage form Box of 1 blister x 14 tablets
Specifications Montelukast

Ingredient

Composition information	Content
Montelukast	5mg

Uses

Indications

Prophylaxis and treatment of chronic asthma in adults and children ≥ 12 months.

Reduce symptoms of allergic rhinitis (seasonal allergic rhinitis in adults and children ≥ 2 years) and perennial allergic rhinitis in adults and children over 6 months.

Pharmacokology

Pharmacological group: Leukotriene receptor antagonistic drugs.

ATC code: R03DC03.

Montelukast is a selective Leukotriene receptor counterclock with prolonged effect time. It inhibits the cysteinyl leukotriene type-1 receptor (CYSLT1) found in human airway and on inflammatory cells. The cohesion of CYSLTS in Leukotriene receptors is associated with the pathophysiology of asthma, including smooth muscle contraction, airway edema and inflammation; CYSLTS is released from the nasal mucosa after exposure to allergens, related to the symptoms of allergic rhinitis.

pharmacokinetics

Montelukast's peak plasma concentration achieved after 2-4 hours after drinking. The average oral bioavailability is 64%.

Montelukast links> 99% with plasma proteins.

The drug is widely metabolized by the isoenzyme Cytochrome P450 CYP3A4, CYP2A6 and CYP2C9 and is excreted mainly through the molasses. Metabolism and elimination of prolonged talva in mild patients to medium liver failure.

Before taking Chewing Montemax 5mg ATCO treat chronic asthma (1 blister x 14 tablets)

How to use 2>

Take Montemax 1 time/day.

For asthma, take medicine in the evening.

For allergic rhinitis, the drug use time can be adjusted to each individual to suit the needs of the patient. Patients with asthma and allergic rhinitis should only take 1 tablet daily in the evening.

Dosage

Treatment of asthma and allergic rhinitis:

Adults and children over 15 years old: 2 capsules (10 mg) per day.

Children from 2 - 15 years old: 1 tablet (5 mg) per day.

Children from 2 - 5 years old: 4 mg per day.

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.What to do when overdose?

Management: Support treatment.

In an emergency, call the 115 emergency center immediately or go to the nearest local health station.

What to do when you forget a dose? However, if close to the next dose, skip the forgotten dose and take the next dose at the time as planned. Note that it should not be used double the prescribed dose.

Side Effects

Unknown frequency

Neurological: Change behavior (Example: agitation, anxiety, depression, abnormal dreams, murdering disorders).

immunity: Non -blood leukemia, vascular inflammation with eosinophilic granulocytes, polyaritis (Churg - Strauss syndrome).

Ear and maze: Ear pain, otitis media.

eyes: nearsightedness, conjunctivitis. digestive: diarrhea, nausea, vomiting, abdominal pain, indigestion, gastritis. general disorder: fever.

Infections and infections: viral infections, tooth infections. liver: Increased serum transaminase concentration (ALT, AST). nerve: headache, drowsiness, dizziness.

Respiratory, chest and mediastinum: upper respiratory infection, cough, acute bronchitis, influenza, laryngitis, sore throat, pharyngitis, sinusitis, sinusitis, pneumonia.

skin and subcutaneous tissue: rash, atopic dermatitis, eczema, skin infection, urticaria. blood vessels: nosebleeds.

Instructions on how to handle ADR

When experiencing side effects of the drug, it is necessary to stop using and notify the doctor or go to the nearest medical facility for timely treatment.

Warnings

Contraindicated

contraindicated drugs in the following cases:

Hypersensitivity to any component of Montemax.

Be cautious when using

Montelukast's treatment effect on Hen's test parameters will be achieved within 1 day. It is necessary to tell patients to continue using Montelukast, although asthma attacks have been controlled, as well as in periods of severe asthma.

No dose adjustment for patients with renal impairment, mild and medium liver failure, elderly people, or for each gender.

Patients with aspirin sensitive asthma must continue to avoid taking aspirin and other NSAIDs.

Not used to treat acute asthma attacks.

Do not encourage the use of single therapy in the treatment of chronic asthma level.

Montemax can be used in combination with other treatments.

Dosage of combined drugs: bronchodilators, inhaled or oral corticosteroids. Do not suddenly replace corticosteroids inhaled or taken with Montelukast.

Regularly monitor signs and symptoms of behavioral changes.

Used in the elderly: There is no overall difference in safety or efficiency between the elderly and young people, but it cannot eliminate higher sensitivity in some others.

The ability to drive and operate machinery

This drug can cause dizziness or drowsiness, if affected, do not drive or operate machinery.

During pregnancy

There is no adequate and controlled research in pregnant women, so only Montemax should only be used during pregnancy when necessary.

The period of breastfeeding

It is not known whether Montelukast will be excreted through breast milk. Because many drugs are excreted in breast milk, it is cautious when prescribing Montemax for nursing mothers.

Model interaction

Caution, especially in children, when coordinating the CYP3A4 touch combination (such as phenytoin, phenobarbital, rifampicin).

Gemfibrozil can increase the concentration of Montelukast in serum.

Storage

Store at a temperature not exceeding 30 ° C. Avoid moisture and direct light.

Other drugs

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