Chlorpheniramin 4mg fourdiphar treatment of allergic rhinitis, urticaria (10 blisters x 20 tablets)
Dosage form Tablet
Specifications Box of 10 blisters x 20 tablets
Ingredient Chlorpheniramine
Ingredient
| Composition information | Content |
| Chlorpheniramine | 4mg |
Uses
indications
chlorpheniramin 4mg fourdiphar used in the treatment of seasonal and year -round allergic rhinitis. Other allergic symptoms such as urticaria, vasculitis caused by histamine, allergic conjunctivitis, contact dermatitis, angioedema, quincke edema, food allergies, serum reactions; Insect -burned insects; Itching in patients with measles or chickenpox.
Pharmacokology
chlorpheniramine is an antihistamine drug. Like most other antihistamines, chlorpheniramine also has side effects against acetylcholin secretion, but this effect varies greatly among individuals. The antihistamine effect of chlorpheniramine through the block of the h1 receptor of the acting cells.
Dynamic pharmacokinetics
Clorpheniramin Maleat absorbs well when drinking and appears in plasma within 30-60 minutes. Plasma peak concentration reaches about 2.5 hours to 6 hours after drinking. Low biological use, reaching 25-50%. About 70% of the drug during the circulation associated with protein.
chlorpheniramin maleat is fast and high. The metabolites include Desmethyl-Didesmethyl-Clorpheniramin and some unknown substances, one or more substances of which are active. The drug is excreted mainly in urine in the form of constant or metabolic, the excretion depends on the pH and the urine flow. Only a small amount is seen in the feces. The sale time is 12 - 15 hours and in people with chronic renal failure, lasting up to 280 - 330 hours.
Before taking Chlorpheniramin 4mg fourdiphar treatment of allergic rhinitis, urticaria (10 blisters x 20 tablets)
How to use
Chlorpheniramin oral medication.
Dosage
Adults: 1 capsule/time, 3-4 times/day. Every day not more than 6 tablets.
Children 6 - 12 years old: 1/2 tablets/time, 2-3 times/day.
Children under 6 years of age: According to the instructions of the physician.
Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.What do
do when using overdose? Symptoms and overdose signs include sedation, inverse stimulation often TKTW, mental disorder, seizures, apnea, convulsions, anti -secretion effects Acetylcholin, hypertonic reaction and cardiovascular collapse, arrhythmia.
Treatment: Treatment of symptoms and supporting life function, special attention should be paid to liver, kidney, respiratory, heart and water balance.
In an emergency, call the 115 emergency center immediately or go to the nearest local health station.
What to do when you forget 1 dose? However, if the time to relax with the next dose is too short, skip the dose and continue the calendar of the drug. Do not use double dose to compensate for missed dose.
Side Effects
Sedative effects are very different from sleeping chicken to deep sleep, dry mouth, dizziness and irritation occurs when interrupted treatment. However, most patients suffer from side effects when treating continuously, especially if increasing the dose slowly.
Notify the doctor with unwanted effects when using the drug.
Warnings
Before using the drug you need to read the instructions carefully and refer to the information below.
Contraindicated
Chlorpheniramine drugs are contraindicated in the following cases:
Be cautious when using
chlorpheniramine may increase the risk of urinary urination due to anti -anti -secretion side effects of the drug, especially in people with prostate hypertrophy, urinary tract, pyloric garges and worsen in patients with muscle weakness.
The sedative effect of chlorpheniramin increases when drinking alcohol and when used simultaneously with other sedatives.There is a risk of respiratory complications, respiratory decline and apnea, which can cause trouble in people with pulmonary obstruction or children. Must be cautious when there is chronic lung disease, shortness of breath or shortness of breath.
There is a risk of tooth decay in patients for long -term treatment, due to anti -secretion effects, causing dry mouth.
Avoid using people who are driving or controlling machines.
Avoid using patients with glaucoma as glaucoma.
Use medication carefully with the elderly (greater than 60 years old) because these people often increase sensitivity to anti -secretion effects acetylcholin.
The effect of the drug on the ability to drive and operate machinery
Drugs that cause drowsiness should pay attention when used for drivers and people operating machinery.
Use drugs for women during pregnancy and lactation
Pregnancy: Only for pregnant women when really necessary. Do not take the drug in the last 3 months of pregnancy.
Breastfeeding period: Clorpheniramin can be secreted through breast milk and inhibit milk. Because antihistamine drugs can cause serious reactions to breastfed babies, it is necessary to consider or not breastfeed or do not take the drug, depending on the level of the medication for the mother.
Interactive drug
Monoamine oxydase inhibitors prolonged and increased anti -secretion effect of acetylcholine of antihistamine drugs.
ethanol or sedative drugs can increase the effect of inhibiting the central nervous system of chlorpheniramin.
chlorpheniramine inhibits phenytoin metabolism and can lead to phenytoin poisoning.
Storage
Leave a cool place, avoid light, temperature below 30⁰C.
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