Chlorpheniramine 4mg Mekophar medicine for allergic and year -round rhinitis (5 blisters x 20 tablets)

Dosage form Tablet
Specifications Box of 5 blisters x 20 tablets
Ingredient Chlorpheniramin maleat
Indication Rhinitis, allergic rhinitis, itching, stuffy nose

Ingredient

Composition informationContent
Chlorpheniramin maleat4mg

Uses

Indications

Chlorpheniramin 4mg drugs are indicated in the following cases:

Seasonal and year -round allergic rhinitis.

Other allergy symptoms:

  • urticaria, vascular rhinitis caused by histamine, allergic conjunctivitis, contact dermatitis, angioedema, rhyme, food allergies, serum reactions. The mixture of optical polyclosure has an average antihistamine, sedative but also stimulated, especially in young children and Muscarin resistance. Clopheniramin Maleat derived from Alkylamin is antihistamine sedation of the first generation. Chlorpheniramine reduces or loses the main effects of histamine in the body by competing in the clutches with reversed histamine in H1 receptors in the tissues on the digestive tract, vascular and respiratory tract; The drug does not lose the activity of histamine or prevent synthesis or release of histamine.

    pharmacokinetics

    chlorpheniramin maleat absorbs well but relatively slow because the drug is high in the gastrointestinal mucosa and initially metabolic in the liver when drinking and appearing in plasma within 30-60 minutes. Plasma peak concentration reaches 2.5 to 6 hours after drinking.

    About 25 - 45% of the single dose is completely in the form of non -metabolic drugs. Low bioavailability, reaching 25-50%.

    About 70% of the drug during the circulation associated with protein.

    chlorpheniramin maleat is fast and high. The metabolites include Desmethyl-Didesmethyl-Chlorpheniramin and some unknown substances, one or more of which are active.

    The effect of the drug lasts from 4 to 6 hours, shorter than expected compared to the pharmacokinetic parameters. The drug is excreted mainly in urine in a constant or metabolic form, the excretion depends on pH and urine flow.

    • Before taking Chlorpheniramine 4mg Mekophar medicine for allergic and year -round rhinitis (5 blisters x 20 tablets)

    How to use

    Take orally, can be taken or not with food.

    Dosage

    Adults and children over 12 years: 1 tablet, every 4 - 6 hours. Maximum 6 tablets/day.

    Children from 6 - 12 years old: 1/2 tablets, every 4 - 6 hours. Maximum 3 tablets/day.

    Children from 2 - under 6 years old: 1/4 tablets, every 4 - 6 hours. Maximum 1 ½ tablets/day.

    Children under 2 years of age: Use as directed by a doctor.

    Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.

    What to do when overdose?

    If the overdose occurs, it is recommended to go to the nearest medical facility for medical staff to have treatment methods.

    What to do when you forget a dose? However, if close to the next dose, skip the forgotten dose and take the next dose at the time as planned. Note that double dose should not be used.

    Side Effects

    When using chlorpheniramin 4mg you may experience unwanted effects (ADR).

    Common, ADR> 1/100

    No report.

    Uncommon, 1/1000

    No report.

    Rare, ADR

    No report.

    No frequency determination.

  • Neurological: Sleep, sedation, dizziness.
  • Digestive: dry mouth, nausea.

    When experiencing side effects of the drug, it is necessary to stop using and notify the doctor or go to the nearest medical facility for timely treatment.

    • Warnings

    Before using the drug you need to read the instructions carefully and refer to the information below.

    Contraindicated

    Chlorpheniramin 4mg drug contraindicated in the following cases:

  • Hypersensitivity to one of the ingredients of the drug. Monoaminoxydase (IMAO) within the previous 2 weeks.

    • Precautions when using

    Patients with chronic lung disease, shortness of breath or shortness of breath.

    Elderly (> 60 years old) because often increases sensitivity to acetylcholin secretion.

    Avoid using the patient as long as Glaucom.

    chlorpheniramine may increase the risk of urinary urination due to the anti -acetylcholin secretion side effects of special drugs in people with prostate hypertrophy, urinary tract, pyloric garges, and worsen in patients with myasthenia gravis.

    The sedative effect of chlorpheniramine increases when drinking alcohol and when used simultaneously with other sedatives.

    The ability to drive and operate machinery

    The drug can cause chickens, dizziness, dizziness, blurred vision, and dysfunction that can seriously affect the ability to drive or operate the machine. Avoid using drugs for people who are driving or operating machinery.

    Pregnancy

    Pregnant women only use chlorpheniramin when really necessary. Using drugs in the last 3 months of pregnancy can lead to serious reactions (such as epilepsy) in newborns.

    Breastfeeding period

    Medicinal interaction

    Monoamine oxydase inhibitors prolonged and increased the anti -secretion effect of acetylcholine of antihistamine drugs.

    Alcohol, alcoholic products or sedatives that cause sleep can increase the inhibition effect of the TKTW system of chlorpheniramine.

    chlorpheniramine inhibits phenytoin metabolism and can lead to phenytoin poisoning.

    To avoid interactions between drugs, notify the doctor or pharmacist about the drugs being used.

    Storage

    Places dry (moisture ≤ 70%), temperature not exceeding 30 ° C, avoiding light.

    Other drugs

    Disclaimer

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    The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Drugslib.com does not assume any responsibility for any aspect of healthcare administered with the aid of information Drugslib.com provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

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