CIDETUSS IMEXPHARM treats cough cases (10 blisters x 10 tablets)

Dosage form Box of 10 blisters x 10 tablets
Specifications Guiifenesin, Cetirizin, Dextromethorphan
Ingredient Imexpharm Pharmaceutical Joint Stock Company

Ingredient

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Composition information	Content
Guiifenesin	100mg
Cetirizin	5mg
Dextromethorphan	15mg

Uses

Indications

What is the effect of cidetuss medicine? Cidetuss drugs are indicated for treatment of coughs with phlegm, throat and bronchial coughs are irritated when the cold cold or when inhaling the respiratory irritation.

Pharmacokic

GuaiFenesin has a long sputum effect. The mechanism of the effect of Guaifenesin is to stimulate the increased respiratory discharge, thus increasing the vol

Cetirizin is a strong antihistamine, anti -allergy but does not cause drowsiness in pharmacological doses. Cetirizin inhibits the early stage of allergic reactions through histamine intermediaries, reducing the relocation of inflammatory cells and reducing the release of intermediate substances in the late stage of allergic reactions.

dextromethorphan acts on the cough center in the brain, reducing the cough due to mild stimulation in the bronchial and throat as the usual cold or inhaling stimulants. Dextromethorphan has little side effects in the digestive tract.

pharmacokinetic

Guaiifenesin absorbs well through the gastrointestinal tract. 60% of the Guaifenesin is hydrolyzed in the blood within 7 hours. Guiifenesin excreted the kidneys mainly in the form of inactive metabolites, the sale time of about 1 hour.

Cetirizin is poorly absorbed through the gastrointestinal tract, the peak concentration in plasma is achieved after about 1 hour. Food does not affect the ability to absorb the drug but may cause a long time to reach the peak concentration in plasma. Cetirizin is strongly linked to plasma proteins. Cetirizin eliminates the kidneys mostly in the form of constant and excreted breast milk. Selling time is about 10 hours.

Dextromethorphan is quickly absorbed through the digestive tract and works after drinking for 15 - 30 minutes and lasts about 6 - 8 hours. Dextromethorphan is metabolized in the liver, excreted in urine in a constant form and Demethyl metabolites. Dextrorphan, one of the Dextromethorphan demethyl metabolites, also gives a slight cough reduction effect.

Before taking CIDETUSS IMEXPHARM treats cough cases (10 blisters x 10 tablets)

How to use

Oral CIDETUS drugs, before or after meals.

Dosage

Adults and children aged 6 and older:

Take 1 tablet x2 times/day.

Children from 4 to under 6 years old:

Take 1 capsule/day.

Children under 4 years old:

Daceller form and the content of the drug are not suitable for children under 4 years of age.

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.

What to do when overdose?

Guaifenesin

Symptoms: If the Guaifenesin is taken at a higher doses than the normal dose, the card has nausea, vomiting.

Handling: gastric lavage if detected early, treated symptoms.

cetirizin

The most common symptom of Cetirizin overdose is to sleep in adults, in children that may be agitated. In serious overdose, it is necessary to cause vomiting and gastric lavage along with supportive methods. Currently, there is no specific antidote.

dextromethorphan

Symptoms: Nausea, vomiting, drowsiness, blurred vision, eyeball, urination, numbness, hallucinations, regulatory honey, respiratory failure, convulsions.

Treatment: Support, use Naloxon 2mg intravenously, for reminders if necessary, maximum total dose of 10mg.

What to do when you forget the dose? However, if close to the next dose, skip the forgotten dose and take the next dose at the time as planned. Do not drink twice as prescribed.

Side Effects

When using Acehasan 100, you may experience unwanted effects (ADR). Some of the side effects recorded in research on users of this drug are:

Guaifenesin:

Rare: Symptoms of dizziness, headache, diarrhea, vomiting or nausea, abdominal pain, skin rash, urticaria, kidney stones have been reported in patients with abuse of preparations containing Guaifenesin.

cetirizin:

Common

: The phenomenon of chicken sleep and the rate of occurrence depends on the dose. In addition, Cetirizin can cause fatigue, dry mouth, sore throat, dizziness, headache, nausea.

Uncommon: Anorexia or appetite, urinary retention, flushing and increasing salivation.

dextromethorphan:

Common: fatigue, dizziness, tachycardia, flushing.

Uncommon: urticaria.

Rare: Cases of skin rash. Occasionally can sleep slightly, digestive disorders.

This is not a full portfolio of all side effects and may occur other side effects. If you encounter any unwanted effect, stop taking the medication and immediately notify your doctor or immediately go to the nearest medical facility for timely treatment.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

Contraindicated

CIDETUSS anti -contraindications in the following cases:

Sensitive people with any ingredients of the drug.

Pregnant and lactating women.

Children under 4 years old.

Patients are using Monoamin Oxydase (Mao).

Caution when taking drugs

Precautions when using drugs for patients with coughs with too much phlegm and prolonged or chronic cough in smokers, asthma, gas overflow, chronic bronchitis, pulse or cough with too much sputum.

Adjust the dose in patients with liver failure, medium and severe renal failure, or patients with artificial kidneys.

Avoid using drugs in patients with porphyrin metabolic disorders caused by Guiifenesin causing porphyrin metabolic disorders on experimental animals.

Caution in patients at risk or respiratory decline.

Avoid using drugs with alcohol and central neurological inhibitors.

Abuse of the guidenesin drug can cause kidney stones.

Abuse and dependence on dextromethorphan may occur (though rare), especially when taking high doses. Patients need adequate rehydration during the use of the drug. Do not arbitrarily use the drug for more than 7 days without consulting the doctor.

The ability to drive and operate machinery

Avoid using drugs for patients with train drivers and operating machinery due to drugs that can cause drowsiness and sleep.

Pregnancy and lactation

Pregnancy

Due to the inadequate research data on drug use for pregnant women, it is necessary to avoid drugs for these subjects to ensure safety for young children. If necessary, please consult your doctor to consider benefits and risks.

Breastfeeding period

Due to the inadequate research data on the use of drugs for nursing women, it is necessary to avoid drugs for these subjects to ensure safety for young children. If necessary, please consult your doctor to consider the risk benefits.

Medicinal interaction

CIDETUSS may change the ability of other drugs you are taking or increase the effects of side effects. To avoid drug interactions, it is best to write a list of drugs you are taking (including prescription, non -prescription, herbal and functional foods) and to the doctor or pharmacist. To ensure safety when taking the drug, you do not arbitrarily take the drug, stop or change the dosage of the drug without the permission of a doctor.

Avoid taking drugs with Monoamin oxydase inhibitors (Mao).

Theophylin mitigates the clearance of cerimizin when shared.

The central neurological inhibitory effect may increase when used simultaneously dextromethorphan and central neurological inhibitors.

Dextromethorphan is metabolized through the Cytochrom P450 enamel system, mainly CYP2D6. Be cautious when using the drug at the same time with metabolic enzyme inhibitors such as amiodaron, haloperidol, propafenon, quinidine, serotonin selective inhibitors (SSRIs) because of the risk of increasing serum dextromethorphan levels, leading to increased dextromethorphan effects.

Using Guaifenesin may give a fake positive result in the vanilylmandelic acid test in urine. 48 -hour Guaifenesin should be stopped before taking this urine for this test.

Storage

You should store cidetuss drugs at room temperature, avoid moisture and avoid light. No storage in the bathroom or in the freezer. You should remember that each drug may have different storage methods. Therefore, you should read carefully storage instructions on the packaging or ask the pharmacist.

Keep pills out of reach of children and pets.

Expiry date: 24 months from the date of manufacture.

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