Coldacmin Flu DHG medicine treats symptoms of fever, headache, muscle aches (10 blisters x 10 tablets)

Dosage form Hard capsules
Specifications Box of 10 blisters x 10 tablets
Ingredient Paracetamol, chlorpheniramine
Indication Allergic rhinitis, fever, cold
Contraindication Prostate fibroids, acute renal failure, chronic renal failure, liver failure

Ingredient

Composition information	Content
Paracetamol	325mg
Chlorpheniramine	2mg

Uses

Indications

Coldacmin Flu drug is indicated in cases of symptomatic treatment cases: fever, headache , muscle aches, joints with nasal congestion, runny nose, rhinitis, mucous mucous membrane, sinusitis due to flu or allergies.

Pharmacokinus

paracetamol is an analgesic - antipyretic. The drug acts on the central cashew center in the hypothalamus causing cooling, increasing heat due to vasodilation and increasing peripheral blood flow reduces body temperature in people with fever, but rarely reduces body temperature in normal people. Paracetamol relieves pain by raising the threshold of pain.

Clorpheniramin Maleat is an anti -anti - drug, through the H1 receptor inhibitor under the competitive mechanism, which leads to reducing edema, floating in hypersensitivity reactions such as allergies and anaphylaxis. Chlorpheniramin also has anti -anti -cholinergic effects.

pharmacokinetic

Paracetamol absorbs quickly and almost completely through the gastrointestinal tract. The sale time is 1.25 - 3 hours. Metabolic drugs in the liver into N - Acetyl - Benzoquinonimin and are eliminated through the kidneys.

chlorpheniramin maleat is well absorbed by oral. The drug is metabolized fast and much. The drug is excreted mainly in urine in the form of constant or metabolic, the excretion depends on the pH and the urine flow. The sale time of chlorpheniramin is 12 - 15 hours.

Before taking Coldacmin Flu DHG medicine treats symptoms of fever, headache, muscle aches (10 blisters x 10 tablets)

How to use

How to drink every 4-6 hours. Take Coldacmin FLU full medicine with a glass of water.

Read the user manual carefully before use.

Dosage

Adults and children over 12 years:

Take 1 - 2 capsules/time.

Children from 6 to 12 years old:

Take Coldacmin Flu half a dose of adults.

or used as directed by the physician. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.

What to do when overdose? Liver necrosis depends on the dose is the most serious toxic effect due to overdose and can be fatal.

Manifestations of paracetamol overdose: Nausea, vomiting, abdominal pain, symptoms of blue -purple skin, mucosa and nails.

How to handle: When paracetamol poisoning is severe, it is necessary to treat actively. Need to wash the stomach in any case, preferably within 4 hours after drinking.

The main detoxification is the use of sulfhydryl compounds. N - Acetylcystein works when taken or intravenously. Must give the drug immediately if less than 36 hours after taking paracetamol. Treatment with N - Acetylcystein is more effective when giving the drug for less than 10 hours after taking paracetamol. When drinking, dilute N - Acetylcystein solution with water or drinks without alcohol to achieve a 5% solution and must be taken within 1 hour after mixing. Give N - Acetylcystein with the first dose of 140 mg/kg body weight, then give 17 more doses, each dose of 70 mg/kg body weight every 4 hours apart.

In addition, methionine, activated carbon and/or salted carbon.

Expression of overdose chlorpheniramin: sedation, mental disorder , seizure, apnea, convulsions, anti -secretions of acetylcholin, ...

How to handle:

Stomach or vomiting with ipecacuanha syrup. Then, use activated carbon or bleach to limit absorption. When experiencing hypotension and arrhythmia, it should be actively treated. It is possible to treat convulsions with intravenous diazepam or phenytoin intravenously. May have to be blood transfusion in heavy cases.

What to do when forgetting 1 dose? However, if the time to relax with the next dose is too short, skip the dose and continue the calendar of the drug. Do not use double dose to compensate for missed dose.

Side Effects

When using Coldacmin Flu, you may experience unwanted effects (ADR) such as:

Allergic reactions, vomiting, nausea, rash, neutropen leukopenia, thrombocytopenia and all bloody reduction.

can cause liver failure (due to cancellation of liver cells) when using high -dose paracetamol.

dry mouth , regulatory disorders, urinary retention, sweating, sleeping, sedation.

Instructions on how to handle ADR:

When experiencing side effects of the drug, it is necessary to stop using and notify the doctor or go to the nearest medical facility for timely treatment.

Notify the doctor with unwanted effects when using the drug.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

Contraindicated

Coldacmin Flu medicine is contraindicated in the following cases:

sensitive to one of the ingredients of the drug.

Patients with glucose deficiency - 6 - phosphate dehydrogenase.

Patients with narrow -angle glaucom patients, in acute asthma attack, prostate hypertrophy , bladder neck obstruction, stomach ulcer narrow, pyloric switching, using Mao inhibitors within 14 days.

breastfeeding, infant and childbirth women.

Caution when using

Paracetamol is relatively non -toxic to the dose of treatment. Sometimes there are skin reactions including rugged rash and urticaria; Other sensitive reactions include larynx edema, angioedema, and anaphylactic reactions that may rarely occur. Platelets, leukopenia, and all bloody hematuria have occurred with the use of p - aminophenol derivatives, especially when used for large doses. Neutral leukopenia and thrombocytopenic hemorrhage occur when using paracetamol. Rarely loss of granulocytes in patients using paracetamol.

For people with phenylceton - urinary and people must limit the amount of phenylalanin put into the body, should avoid using paracetamol with drugs or foods containing aspartam. For some hypersensitivity people ( asthma ) should avoid using paracetamol with drugs or foods containing sulfit. Precautions must be used in patients with anemia before, impaired liver and kidney function. Drinking plenty of alcohol can cause toxicity to the liver of paracetamol, should avoid or limit drinking.

Clorpheniramine may increase the risk of urinary retention, especially in people with prostate hypertrophy, urinary tract congestion, duodenal pylorus, and exacerbate in people with myasthenia gravis . The sedative effect of chlorpheniramine increases when drinking alcohol and when used simultaneously with other sedatives. Be cautious when used for people with chronic lung disease, shortness of breath or shortness of breath, people with glaucoma, elderly people. The risk of tooth decay when used for a long time.

For Paracetamol-containing drugs: Doctors need to warn patients on signs of serious skin reactions such as Steven-Johnson syndrome (SJS), toxic skin necrosis syndrome (Ten) or Lyell syndrome, acute pustular syndrome (AGEP).

The ability to drive and operate machinery

The drug can affect the ability to drive and operate machinery. Avoid using Coldacmin Flu for this object.

Pregnancy

only use Coldacmin Flu when it is really necessary. Using chlorpheniramine in the last 3 months of pregnancy can lead to serious reactions (such as epilepsy) in newborns.

Breastfeeding period

Should consider or do not breastfeed or do not take Coldacmin Flu medicine, depending on the need for the mother for the mother.

Drug interaction

Do not share Coldacmin Flu with the following drugs:

Antibiotics cooumarin and indandion, phenothiazin. Monoamin oxidase inhibitors.

Storage

In a dry place, the temperature does not exceed 30 ° C, avoiding light.

To be out of reach of children.

Other drugs

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