Coldacmin FLU DHG medicine treats symptoms of fever, headache, muscle aches (100 tablets)

Dosage form Hard capsules
Specifications Box of 100 capsules
Ingredient Acetaminophen, chlorpheniramine
Indication Allergic rhinitis, sinusitis, fever, colds, headache, body aches
Contraindication Prostate enlargement, anuria

Ingredient

Composition information	Content
Acetaminophen	325mg
Chlorpheniramine	2mg

Uses

Indications

Coldacmin Flu drug is indicated in the following cases:

Fever;

headache;

muscle aches, osteoarthritis accompanied by stuffy nose, runny nose, rhinitis, mucous membrane secretion, sinusitis caused by the flu or allergies to the weather. The drug acts on the central cashew center in the hypothalamus causing cooling, increasing heat due to vasodilation and increasing peripheral blood flow reduces body temperature in people with fever, but rarely reduces body temperature in normal people. Paracetamol relieves pain by raising the threshold of pain.

Clorpheniramin Maleat is an antihistamine drug, through H1 receptor inhibition according to the competitive mechanism, which leads to reducing edema, urticaria in hypersensitivity reactions such as allergies and anaphylaxis. Chlorpheniramin also has anti -anti -cholinergic effects.

pharmacokinetic

Paracetamol absorbs quickly and almost completely through the gastrointestinal tract. The sale time is 1.25 - 3 hours. Metabolic drugs in the liver into N - Acetyl - Benzoquinonimin and are eliminated through the kidneys.

chlorpheniramin maleat is well absorbed by oral. The drug is metabolized fast and much. The drug is excreted mainly in urine in the form of constant or metabolic, the excretion depends on the pH and the urine flow. The sale time of chlorpheniramin is 12 - 15 hours.

Before taking Coldacmin FLU DHG medicine treats symptoms of fever, headache, muscle aches (100 tablets)

How to use

How to drink every 4-6 hours.

Dosage

Adults and children over 12 years old: take 1-2 capsules/time.

Children from 6 - 12 years old: Take half a dose of adults or as directed by the physician.

Read the user manual carefully before use.

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.

What to do when overdose?

Overdose

Paracetamol overdose due to a single -dose or a repeated dose of a large dose of paracetamol (7.5 - 10 g per day, for 1-2 days) or for long -term medication. Hepatic necrosis due to drug dependence is a serious toxic effect due to overdose and may cause death.

Expression of paracetamol overdose:

nausea;

vomit;

When Paracetamol poisoning is severe, it is necessary to treat positively, need gastric wash in all cases, preferably within 4 hours after drinking. Gastric or vomiting with ipecacuanha syrup. Then, use activated carbon or bleach to limit absorption. In the case of hypotension and arrhythmia, it should be actively treated. It is possible to treat convulsions with intravenous diazepam or phenytoin intravenously. May have to be blood transfusion in heavy cases.

The main detoxification is the use of sulfhydryl compounds. N - Acetylcystein works when taken or intravenously. Must detoxify immediately if less than 36 hours after taking paracetamol. Treatment with N - Acetylcystein is more effective when giving the drug for less than 10 hours after taking paracetamol. When drinking, dilute N - Acetylcystein solution with water or drinks without alcohol to achieve a 5% solution and must be taken within 1 hour after mixing. Give N - Acetylcystein with the first dose of 140 mg/kg body weight, then give 17 more doses, each dose of 70 mg/kg body weight every 4 hours apart.

In addition, methionin can be used, activated carbon and/or salt bleach.

Expression of overdose chlorpheniramin: sedation, mental disorder, seizure, apnea, convulsions, anti -secretion effects Acetylcholin ...

What to do when you forget a dose? However, if close to the next dose, skip the forgotten dose and take the next dose at the time as planned. Note that it should not be used double the prescribed dose.

Side Effects

When using Coldacmin Flu, you may experience unwanted effects (ADR).

The reaction includes:

allergies, vomiting.

Nausea. Users may have:

bad breath.

Regulating disorders.

When experiencing side effects of the drug, it is necessary to stop using and notify the doctor or go to the nearest medical facility for timely treatment.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

Contraindicated

Coldacmin Flu medicine is contraindicated in the following cases:

Hypersensitivity to one of the ingredients of the drug.

Patients with glucose deficiency - 6 - phosphate dehydrogenase.

Patients with narrow -angle glaucom patients, in acute asthma attacks, prostate hypertrophy, bladder neck obstruction, stomach ulcers, pyloric - duodenal blockage, use Mao inhibitors within 14 days.

Lactating women, newborns and childbirth.

Caution when using

Paracetamol is relatively non -toxic to the dose of treatment. Sometimes there are skin reactions including rugged rash and urticaria; Other sensitive reactions include larynx edema, angioedema, and anaphylactic reactions that may rarely occur. Platelets, leukopenia, and all bloody hematuria have occurred with the use of p - aminophenol derivatives, especially when used for large doses. Neutral leukopenia and thrombocytopenic hemorrhage occur when using paracetamol. Rarely loss of granulocytes in patients using paracetamol.

For people with phenylceton - urinary and people must limit the amount of phenylalanin put into the body, should avoid using paracetamol with drugs or foods containing aspartam. For some hypersensitivity people (asthma) should be avoided with paracetamol with drugs or foods containing sulfit. Precautions must be used in patients with anemia in advance, impaired liver and kidney function, drinking plenty of alcohol can cause toxicity to the liver of paracetamol, should avoid or limit drinking alcohol.

Clorpheniramin may increase the risk of urinary retention, especially in people with prostate hypertrophy, urinary tract obstruction, pyloric gaster, and worsen in patients with myasthenia gravis. The sedative effect of chlorpheniramine increases when drinking alcohol and when used simultaneously with other sedatives. Be cautious when used for people with chronic lung disease, shortness of breath or shortness of breath, people with glaucoma, elderly people. The risk of tooth decay when used for a long time.

For Paracetamol -containing drugs: The doctor should warn the patient about the signs of serious skin reactions such as Stevens - Johnson syndrome (SJS), toxic skin necrosis syndrome (Ten) or Lyell syndrome, acute overseas pustular syndrome (AGEP).

The ability to drive and operate machinery

People who are subject to use.

Pregnancy

Pregnant women: only use drugs when really necessary. Using chlorpheniramine in the last 3 months of pregnancy can lead to serious reactions (such as epilepsy) in newborns.

breastfeeding period

Lactating women: Should consider or do not breastfeed or do not take the drug, depending on the necessary degree of the drug for the mother.

Drug interaction

Do not share Coldacmin Flu with the following drugs:

Coumarin antibodies;

Indandion derivatives; other;

Monoamine inhibitors.

Storage

The drug must be stored in a dry place; The temperature does not exceed 30 ° C and avoids light.

Other drugs

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