Cordarone 200mg Sanofi medicine prevents and treats some types of arrhythmia (30 tablets)

Dosage form Box of 2 blisters x 15 tablets
Specifications Amiodarone
Ingredient Esophageal ulcer

Ingredient

Composition information	Content
Amiodarone	200mg

Uses

Indications

Cordarone 200mg drug is indicated in cases of prevention and treatment of some types of arrhythmia.

Pharmacokology

Anti -arrhyths properties:

extended the third phase of the voltage of myocardial fiber, mainly reducing the potassium line (Group III according to the Vaughan Williams classification); This impact is not antagonistic by atropine; The faster the rhythm of this effect is clearer;

Reduce oxygen consumption through moderate reduction of peripheral resistance and heart frequency reduction; Slowly absorbed and high tissue affinity. Oral bioavailability varies depending on each person from 30 to 80% (average value of 50%). After the single dose, the peak concentration in plasma is achieved for 3-7 hours. Treatment activity is usually achieved for about 1 week (from a few days to 2 weeks). Amiodarone has a long half -life varies depending on the patient (from 20 to 100 days). In the first days of treatment, the drug accumulated in most body tissues, especially adipose tissue. The excretion begins after a few days and the balance between the amount of entry/release is achieved after 1 or several months, depending on the patient. These characteristics prove that the dose is needed to ensure the drug quickly penetrates into the tissue to achieve therapeutic activity.

Through urine excretion should be used in normal doses for patients with renal impairment. After stopping treatment, the excretion continues for a few months. It should be noted that the residual impact lasts more than 10 days to 1 month.

Before taking Cordarone 200mg Sanofi medicine prevents and treats some types of arrhythmia (30 tablets)

How to use

cordarone 200mg oral use.

Take medicine before, during or after meals; Chewing tablets also does not change the properties of the drug.

Dosage

The usual dose varies depending on the patient, but usually:

When starting treatment: 1 tablet each time, 3 times a day, used for 8-10 days.

Even if you stop the medicine, you must consult your doctor.

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, patients need to consult a doctor or medical specialist.

What to do when overdose?

The amiodarone overdose is less noted. Some cases such as heartbeat, ventricular arrhythmia, especially torsion and liver failure have been reported. Symptomatic treatment should be treated. Due to the dynamics of the drug, the tracking time should be long enough, especially the function of the heart.

Amiodarone and its metabolites cannot be separated.

What to do when forgetting a dose? However, if close to the next dose, skip the forgotten dose and take the next dose at the time as planned. Do not drink twice as prescribed.

Side Effects

When using Cordarone 200mg, patients may experience unwanted effects (ADR).

Very common, ADR> 1/10

Eye: visual disorders (feeling of fog or halo around the object).

Skin: Skin reactions with light. rebellion).

Common, 1/10

Skin: The skin is gray. Chi).

Heart: Heart transmission disorders.

Eye: blurred or reduced vision. Blood.

Kidney: Kidney damage.

Unknown frequency:

Respiratory: pulmonary hemorrhage is often with shortness of breath.

When experiencing side effects of the drug, it is necessary to stop using and notify the doctor or go to the nearest medical facility for timely treatment.

Warnings

Before using the drug, patients need to read the instructions carefully and refer to the information below.

Contraindicated

Cordarone 200mg drug contraindicated in the following cases:

allergic allergies to iodine or amiodarone, or one of the drug components. The potential to cause torsion (severe arrhythmia). Cisapride, Diphemanil, intravenous dolasetron, intravenous erythromycin, mizolastine, moxifloxacin, spiramycin intravenously, Toremifene, intravenous Vincamine).

Precautions when using

In case of abnormal gas, shortness of breath or dry cough, whether or not it does not affect the total status, fatigue or prolonged or unexplained fever, diarrhea, weight loss, vision pain, or in the case of re -appearing heart rate too fast, tell the doctor who is being treated for patients.

Patients should not take this drug in the case of congenital galactose metabolism, malaria and galactose malabsorption syndrome or lactase enzyme deficiency (rare genetic diseases).

Tránh dùng phối hợp Cordarone với ciclosporin, diltiazem dạng thuốc tiêm, verapamil, một vài thuốc diệt ký sinh trúng (halofantrine, lumefantrine, pentamidine), một số thuốc an thần (amisulpride, chlorpromazine, cyamemazine, droperidol, fluphenazine, haloperidol, Levomepromazine, Pimozide, Pipamperone, Pipotiazine, Servindole, Sulpiride, Sultopride, Tiapride, Zuclopenthixol) and with Methadone.

It is necessary to avoid sunlight during treatment to avoid skin pigmentation reactions.

During treatment, blood tests need to be tested to check the thyroid or liver function.

If the patient is being transplanted with a shaking machine or a pacemaker, consult a treating doctor whether the machine is working correctly or not before or some time after the start of amiodarone or whenever the dose is needed.

Before surgery, notify the anesthetist to know that the patient is taking amiodarone.

Unknown effectiveness and safety when using Amiodarone for children.

The ability to drive and operate machinery

does not affect.

Pregnancy

Due to the presence of iodine, this drug is contraindicated for pregnant women from the 4th month onwards.

Breastfeeding period

Drug interaction

In order to avoid interactions that may occur between drugs, patients must notify the patient's doctor or pharmacist fully all other treatments that the patient is following.

Cordarone is not used in combination with drugs that can cause peaks (severe arrhythmia) such as some anti -arrhythmia (quinidine, hydroquinidine, disopyramide, dofetilide, ibutilide, sotalol), or with other drugs (Arsenious Trioxide, BePridil, Cisapride, Diphemanil, DoLasete, Dolasete Valids, intravenous erythromycin, mizolastine, moxifloxacin, spiramycin intravenously, Toremifen, intravenous vincamine).

Tránh dùng phối hợp Cordarone với ciclosporin, diltiazem dạng thuốc tiêm, verapamil, một vài thuốc diệt ký sinh trùng (halofantrine, lumefantrine, pentamidine), một số thuốc an thần (amisulpride, chlorpromazine, cyamemazine, droperidol, fluphenazine, haloperidol, Levomepromazine, Pimozide, Pipamperone, Pipotiazine, Servindole, Sulpiride, Sultopride, Tiapride, Zuclopenthixol) and with Methadone.

List of excipients need to know to avoid the risk of drugs for some patients: lactose.

Storage

Store drugs at temperatures not exceeding 30 ° C.

Other drugs

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