DAIVONEX ointment 30g climbing psoriasis psoriasis

Dosage form Tube x 30g
Specifications Calcipotriol
Ingredient Invida (Singapore) Private Limited

Ingredient

Thành phần cho 1g

Composition information	Content
Calcipotriol	50mcg

Uses

Indications

daivonex drugs are indicated in cases of on -site treatment of psoriasis (regular psoriasis). The drug can be used in combination with acitretin, cyclosporin or local corticosteroids.

Pharmacokological

Calcipotriol is the derivative of vitamin D. In vitro data shows that calcipotriol creates a difference and prevents the growth of horn cells but has little effect on calcium metabolism. This impact is the basis for the effects of psoriasis.

pharmacokinetics

Low skin absorption but when entering the general circulatory system, it is quickly transformed into non -active substances.

Before taking DAIVONEX ointment 30g climbing psoriasis psoriasis

How to use

Apply ointment to the skin damaged daily 1 to 2 times. Starting usually applies 2 times/day. May be reduced 1 time/day when appropriate.

Dosage

Adults

Maximum dose per week should not exceed 100g.

Use daivonex twice a day in combination with cyclosporin or acitretin and use daivonex once a day in combination with corticosteroids (such as daivonex morning and steroids in the evening) will be effective and well tolerated.

Use daivonex 2 times a day will increase the effectiveness and reduce the dose of cyclosporin and acitretin.

Children

Children over 12 years: daivonex should be used for damaged skin 2 times daily. The maximum dose per week does not exceed 75g. The maximum dose per week does not exceed 50g. Maximum safety dose has not been determined.

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.

What to do when overdose?

What to do when you forget the dose? However, if close to the next dose, skip the forgotten dose and take the next dose at the time as planned. Do not use double the prescribed dose.

Side Effects

When using daivonex, you may experience unwanted effects. Some of the side effects recorded in research on users of this drug are:

Very common:> 1/10

or meet:> 1/100 and

less common:> 1/1,000 and

rare:> 1/10,000 and

very rare:

The most unwanted effect is the most common response on leather and diverse reaction At the place of use. Các phản ứng dị ứng và tăng canxi - huyết rất hiếm được báo cáo. Based on the clinical data of Daivonex ointment, about 15% of patients have experienced unwanted reactions.

often experience itching, skin irritation, pain and redness, dry skin, erythema and rash. Exposure dermatitis, eczema and psoriasis seriously occur.

The whole body impact after local use causes hypercalcemia or hypercalcium urine is rarely occurring, see the special notice and warning when using the drug.

after -sales report on daivonex:

Change of transient skin pigmentation, sensitive light reaction and hypersensitivity reaction including urticaria, angioedema, edema around the eye and face are very rarely reported. Dermatitis around the mouth rarely occurs.

According to after -sales report, the total number of reports on unwanted reactions is very rare, about 1 part of 10 thousand cases of treatment.

Unwanted reactions listed by Meddra Soc and unwanted reactions are listed and started with the most common frequency.

Skin and subcutaneous disorders:

itchy;

Skin tissue hyperpigmentation;

loss of skin pigmentation;

Disorders of metabolism and nutrition:

Hypertension;

hyper calcium.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

Contraindicated

daivonex contraindicated in the following cases:

Known to be sensitive to any ingredients of the drug.

Be cautious when taking medicine

Do not apply ointment on the face. Patients need to be instructed on how to use the right drug to avoid applying or accidentally dropping the drug on the face. Need to wash your hands after applying the drug.

Should avoid daivonex for patients with severe renal impairment and severe liver dysfunction.

The risk of hypercalcemia - blood is very low when used as recommended dose. Increasing calcium - blood can occur if the maximum dose is more than 100g. However, blood calcium will quickly return to normal when stopping treatment.

During daivonex treatment, physicians should advise patients to avoid or limit excessive contact with natural and artificial light. Calcipotriol should only be used with ultraviolet rays when doctors and patients find out the benefits that are outstanding potential risks.

Propylene glycol can cause skin irritation.

The ability to drive and operate machinery

Not mentioned.

Pregnancy and lactation

Pregnancy

Safety when used in pregnant women has not been established, although animal research does not show the monster effect. Avoid using drugs for pregnant women unless there is no safer alternative.

Breastfeeding period

There has been no identification of calciumotriol, whether it is excreted through breast milk. If necessary to use the drug, consult a doctor and pharmacist to consider the benefits of the mother and the risk of children.

Medicinal interaction

Medicinal interaction can change the ability of the drug or increase the effects of side effects. It is best to write a list of drugs you are taking (including prescription, non -prescription and functional foods) and for doctors or pharmacists. Do not arbitrarily take the drug, stop or change the dosage of the drug without the permission of a doctor.

Not known about interacting with other drugs of daivonex.

Storage

You should store at room temperature not exceeding 30 degrees Celsius, avoid moisture and avoid light. No storage in the bathroom or in the freezer.

You should remember that each drug may have different storage methods. Therefore, you should read carefully storage instructions on the packaging or ask the pharmacist.

Keep pills out of reach of children and pets.

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Disclaimer

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