DecaZone 12g/60ml Amvipharm Treatment of tremor of cerebral crust (60ml)

Dosage form Box x 60ml
Specifications Piracetam

Ingredient

Composition information	Content
Piracetam	12g

Uses

indications

DecaZone drug is indicated in the following cases:

Coordination to treat tremor of convulsions due to cortical causes.

Pharmacology

Piracetam (The ring of the Gamma Amino - Butyric, GABA acid) is considered to be a substance that has a mental effect (improving the metabolism of nerve cells), although people do not know much about its specific effects as well as its mechanism of action. Even the definition of Hung Tri "Nootropie" is still vague.

In general, the main effects of drugs are called Hung Tri (such as Piracetam, Oxiracetam, Aniracetam, Etiracetam, Pramiracetam, Tenilsetam, Sulotidil, Tamitinol) improve learning and memory ability. Many of these are considered to have a stronger effect on piracetam in terms of learning and memory. It is thought that in ordinary people and functional impaired people, Piracetam directly affects the brain to increase the activity of the brain area (the brain area is involved in the mechanism of awareness, learning, memory, alertness and consciousness).

Piracetam acts on a number of neurotransmitters such as acetylcholin, noradrenalin, dopamin ..., this can explain the positive effect of the drug on learning and improve the ability to perform memory tests.

The drug can change neurotransmitter and contribute to improving the metabolic environment so that the nerve cells work well. On experiments, Piracetam has a protective effect against metabolic disorders due to ischemic by increasing brain resistance to oxygen deficiency. Piracetam increases glucose mobilization that does not depend on oxygen supply, facilitates the pentose path and maintains energy synthesis in the brain.

Piracetam reduces the possibility of platelet accumulation and in case of abnormal erythrocytes, the drug can cause red blood cells to recover the ability to deform and the ability to pass through capillaries: drugs have anti -vibration effects.

Pharmacokinetics

absorption

Birth is nearly 100%. Absorption of drugs does not change when long -term treatment. The distribution volume is about 0.6 liters/kg.

Distribution

Piracetam absorbed into all tissues and may be through the blood - brain, placenta barrier and the membranes used in the kidney. The drug has high concentrations in the cerebral cortex, frontal lobe, top lobe and hydraulic, cerebellum and base nucleus.

Elimination

Semi -selling time in plasma is 4-5 hours; The sale time in cerebrospinal fluid is about 6 hours. Piracetam is not attached to plasma proteins and is excreted through the kidneys in the form of intact. Piracetam clearance coefficient of the kidney in normal people is 86 ml/minute 30 hours after taking more than 95% of the drug excreted in urine. If there is a kidney failure, half a lifetime elimination increases: In patients with completely renal failure and not recovering, this time is 48 - 50 hours.

Before taking DecaZone 12g/60ml Amvipharm Treatment of tremor of cerebral crust (60ml)

How to use

Use intravenously

Dosage

usually use 30 - 160 mg/kg/day, divided evenly 2 or 3-4 times/day.

should take oral medication if the patient is taken. It is also possible to use injection to drink if the injection is stopped.

Severe cases may increase the dose to 12 g/day and use by intravenous line.

Long -term treatment of physical mental syndrome in the elderly: 1.2 - 2.4 g/day. The dose can be high to 4.8 g/day/first week.

Treatment of muscle shock: 7.2 g/day, divided into 2-3 times. Although the response every 3-4 days, an increase of 4.8 g/day to a maximum dose of 20 g/day. After reaching the optimal dose of Piracetam, it is advisable to find a way to reduce the dose of the attached drugs.

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.What do

do when using overdose?

There is no need for special measures to overdose.

What to do when you forget a dose? However, if close to the next dose, skip the forgotten dose and take the next dose at the time as planned. Note that it should not be used double the prescribed dose.

Side Effects

When using decazone, you may experience unwanted effects (ADR).

Common, ADR> 1/100

Body: Fatigue.

digestion: Nausea, vomiting, diarrhea, abdominal distention. nerve: restlessness, prone to agitation, headache, insomnia, sleep.

Uncommon, 1/1000

Body: Dizziness.

nerve: Run, sexual stimulation.

Instructions on how to handle ADR

When experiencing side effects of the drug, it is necessary to stop using and notify the doctor or go to the nearest medical facility for timely treatment.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

contraindicated

DecaZone drugs contraindicated in the following cases:

Severe renal failure (Creatinine clearance coefficient below 20 ml/minute).

People with Huntington disease.

Be cautious when used

Because Piracetam is eliminated through the kidneys, the sale time of the drug increases directly to the degree of renal failure and creatinine clearance. It is necessary to be very cautious when taking the drug for people with renal failure. Need to monitor kidney function in these patients and in the elderly.

When creatinine clearance coefficient is below 60 ml/min or when serum creatinine is over 1.25 mg/100 ml, the dose is needed.

Creatinine clearance coefficient is 60 - 40 ml/min or when serum creatinine is 1.25 mg - 1.7 mg/100 ml (half -life of piracetam is twice as long). Only 40% of normal dose should be used.

Creatinine clearance coefficient is 40 - 20 ml/min, serum creatinine is 1.7- 3.0 mg/100 ml (half -life of piracetam is 25 - 42 hours). Use 1/4 normal dose.

The ability to drive and operate machinery

Precautions when taking the drug because the drug can cause chicken sleep.

Pregnancy

Piracetam can be through the placenta. Do not use this medication for pregnant people.

Breastfeeding period

should not use this medication for breastfeeding women.

Drug interaction

can still continue the classic treatment of alcoholic (vitamins and sedatives) in the case of a person with vitamin deficiency or strong agitation. There have been cases of interaction between piracetam and thyroid essence when used simultaneously: confused, stimulated and sleep disorders.

In a patient, prothrombin time has been stabilized by warfarin when using piracetam.

Storage

In a dry place, the temperature does not exceed 30 ° C, avoiding light.

Other drugs

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