Deonas 50mg Korea Prime medicine relaxes skeletal muscles (10 blisters x 10 tablets)

Dosage form Box of 10 blisters x 10 tablets
Specifications Eperison

Ingredient

Composition information	Content
Eperison	50mg

Uses

indications

DEONAS drug is indicated in the following cases:

Stretch the skeletal muscles.

Spastic paralysis in diseases: cerebral vascular disease, spinal spastic paralysis, cervical spondylosis, postoperative sequelae (including cerebrospinal tumors), post -traumatic post -injury (spinal trauma, head lesions), muscle atrophy, cerebellaric cerebellar degeneration, spinal vascular disease, and other brain muscle diseases.

Improve the symptoms of muscle tone in the following diseases: cervical vertebra syndrome, shoulder arthritis, back pain.

Pharmacy

Eperisone Hydrochloride increases both muscle relaxation and vasodilation, due to the effects of the drug on the central nervous system and on vascular smooth muscles. Eperisone Hydrochloride has a stable treatment effect in improving the various symptoms related to muscle tone, thanks to cutting the pathological spiral of muscle spasms.

Eperisone Hydrochloride has the main effect on the spinal cord, reducing the marrow reflexes and creates muscle relaxation by reducing the sensitivity of the muscle through the gamma centrifugation system. In addition, the vasodilation effect of the drug increases circulation. Therefore, Eperisone Hydrochloride by a diverse method, cutting the pathological spiral, which has the muscle contraction of blood disorders, then causes pain and leads to an increase in muscle tone. Eperisone Hydrochloride has been shown to be a clinical effective drug in improving the symptoms of muscle tone, such as shoulder spasms, neck vertebra pain, headache, dizziness, lumbar pain and spasticity of the head - may be accompanied by cerebrospinal disease, cervical vertebra syndrome, shoulder and lumbar inflammation.

pharmacokinetics

Eperisone Hydrochloride has been used by oral in healthy adults at a dose of 150 mg/day, for 14 consecutive days. On day 1, 8, and 14, the average time leads to the maximum concentration range from 1.6 to 1.9 hours. The average concentration is 7.5 to 7.9 ng/ml; The average selling time is 1.6 to 1.8 hours and the area under the plasma concentration curve is 19.7 to 21.1 ng. The plasma concentrations of Eperisone Hydrochloride are measured on the 8th and 14th day, there is no significant change compared to the first day.

absorption, distribution, metabolism and elimination

When L4C - Eperisone Hydrochloride (Eperisone Hydrochloride is marked with L4C radiation) used by oral for mice at a dose of 50 mg/kg, most of the drugs absorbed through the gastrointestinal tract and Eperisone Hydrochloride concentration are in a constant form in low plasma. This suggests that the first absorption efficiency is relatively high. After 30 minutes after drinking, the radioactive concentration in the brain, spinal cord, thigh nerves and muscles in the cavity are equal to blood levels. Within the first 5 days after taking the drug, 98% of radioactive has been recovered, 77% from urine, 21% from feces. At 24 hours after drinking, 43% of radioactivity was excreted in bile. This finding shows that Eperisone Hydrochloride participates in the liver -intestinal cycle. That was seen in mice, mice and hunting dogs. Eperisone Hydrochloride is metabolized through hydration of carboxylate, an inactive metabolite.

Before taking Deonas 50mg Korea Prime medicine relaxes skeletal muscles (10 blisters x 10 tablets)

How to use

Deonas drugs are taken orally.

Dosage

The usual dose for adults is 1 tablet, 3 times daily, drink after meals. The dose should be adjusted depending on the age of the patient and the severity of symptoms.

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.

What to do when using overdose?

In case of overdose, stop use of drugs, symptomatic treatment and supportive measures.

What to do when you forget a dose? However, if close to the next dose, skip the forgotten dose and take the next dose at the time as planned. Note that double dose should not be used.

Side Effects

When using Deonas, you may experience unwanted effects (ADR).

Liver: Liver dysfunction rarely occurs. Should monitor liver function. Stop taking the drug if you see abnormal signs.

kidney: rarely occur kidney dysfunction. Should monitor kidney function. Stop taking the drug if you see abnormal signs. blood: The number of red blood cells or hemoglobin values rarely becomes abnormal. Blood tests should be conducted. Stop taking the drug if the abnormal signs occur. DA: Rash rarely occurs when using Deonas. Mental: Symptoms such as insomnia, headache, drowsiness or numbness and tremor rarely occur. Digestive: Nausea and vomiting, anorexia, stomach discomfort, dry mouth, constipation, diarrhea, abdominal pain, abdominal feeling, soft stool, or other digestive disorders rarely occur.

urinary: Urinary retention, bed beams, or other urinary disorders rarely occur. Systemic: rarely weak, dizzy or feel tired or rarely reduce muscle tension.

Instructions on how to handle ADR

When experiencing side effects of the drug, it is necessary to stop using and notify the doctor or go to the nearest medical facility for timely treatment.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

Contraindicated

DEONAS drug is contraindicated in the following case:

Patients with a history of hypersensitivity to any component of the drug.

Precautions when using

weak, dizziness or drowsiness may occur when using this medication. Discontinue or reduce the dose when the first sign of these symptoms. Be careful when taking medication for patients with liver dysfunction. Patients when taking this drug should not drive or control machines.

The ability to drive and operate machinery

Patients when taking this drug should not drive or control machinery.

Pregnancy

Deonas's safety in pregnancy has not been set. Deonas should only be used during pregnancy when the expected benefits are more than possible risks.

Breastfeeding period

Deonas is not recommended for women who are breastfeeding. If used during this time, patients should stop breastfeeding.

Drug interaction

There has been a report on visual disorders that occur after simultaneous use of methocarbamol with Tolperisone Hydrochlorid (a compound with structure similar to Eperisone Hydrochloride).

Storage

Store in a cool dry place at a temperature of less than 30ºC. To be out of reach of children.

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Disclaimer

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