Devomir S.P.M.

Dosage form Tablet
Specifications Box of 3 blisters x 10 tablets
Ingredient Cinnarizine

Ingredient

Composition information	Content
Cinnarizine	25mg

Uses

indications

Devomir 25 mg drug is indicated in the following cases:

Prevention of seasickness, cargo, aircraft.

Prevention and treatment of migraine.

Prevention and treatment of dizziness, nausea due to vestibular disorders, brain vessel spasms.

Treatment maintains symptoms of peripheral circulatory disorders (Raynaud phenomenon, blue -headed green, limp, nutritional disorders, varicose veins, numbness, muscle spasms at night, cold head).

Pharmacokinus

cinnarizin is an antihistamine (H1). The majority of H1 antihistamine drugs also have anti -secretion effects of acetylcholin and sedation. Antihistamine drugs can block receptors at the end of the vestibular and inhibit the activation of histamine and acetylcholine secretion.

In order for the cargo sickness, antihistamine to be a bit less effective than scopolamine (hyosin), but often better tolerated and antihistamine drugs are less sleepy like cinnarizin or cyclizine is often preferred.

cinnarizin is also a calcium antagonist. The drug inhibits blood vessel muscle muscle contraction by blocking calcium channels.

In some countries, cinnarizin is widely prescribed as a brain vasodilator to treat chronic brain vascular diseases with the main indication of cerebral arteries; But random clinical trials about cinnarizin do not come to a clear conclusion.

cinnarizin has been used in the treatment of Raynaud's syndrome, but it is not determined to be effective. Cinnarizin is also used in vestibular disorders.

pharmacokinetics

absorption - distribution

After drinking, cinarizin achieved plasma peak concentrations from 2 - 4 hours.

Metabolism - Elimination

After 72 hours, the drug still eliminates urine. Half of the drug of the drug in young volunteers is about 3 hours.

Before taking Devomir S.P.M.

How to use

Take medicine with water, after meals.

Dosage

Train motion room

Adults: take 1 tablet, 2 hours before the trip. Repeat after every 6 hours.

Children 5 - 12 years old: 1/2 adult dose.

Other cases

Each time 1-2 tablets, 3 times a day. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.

What to do when overdose? Need to consult medical staff.

What to do when you forget a dose? However, if close to the next dose, skip the forgotten dose and take the next dose at the time as planned. Do not drink twice as prescribed.

Side Effects

When using Devomir 25 mg, you may experience unwanted effects (ADR).

Common, ADR> 1/100

Central nerve: Sleeping chicken.

digestive: digestive disorders.

Uncommon, 1/1000

Central nerve: headache.

digestive: dry mouth, weight gain.

Other: sweating, allergic reactions.

Rare, 1/10000

Central nerve: Symptoms of outsiders in the elderly or for long -term treatment.

cardiovascular: reducing blood pressure (high dose).

Instructions on how to handle ADR

Can prevent chicken sleep and digestive disorders, often temporarily, by increasing the dose to the optimal level. The drug must be stopped when the disease is worse or the symptoms of extra -tapers appear when treating for a long time for the elderly.

Notice to the doctor or pharmacist the unwanted effects when using the drug.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

Contraindicated

Devomir 25 mg drug is contraindicated in the following cases:

Not for patients sensitive to any ingredients of the drug.

Porphyrin metabolism.

Be cautious when used

as well as with other antihistamines, cinnarizin can cause epigastric pain. Taking medicine after meals can reduce stomach irritation.

cinnarizin can cause chicken sleep, especially at the beginning of treatment. Must avoid jobs that need alertness (such as driving).

To avoid long -term cinnarizin in the elderly, because it can cause increased or appearing foreign symptoms, sometimes combined with depression in prolonged treatment.

The ability to drive and operate machinery

Do not use drugs while driving and operating machinery.

Pregnancy

only used when necessary.

The period of breastfeeding

only takes cinnarizin during breastfeeding when the benefits of treatment for mothers are more likely to occur for children.

Interactive drug

Do not use drugs with the nervous system inhibitors, three -round antidepressants, alcohol.

Storage

Store in a dry place, avoid light, temperature not exceeding 30 ° C.

Other drugs

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