Dexipharm 15mg Imexpharm drugs for cough symptoms (10 blisters x 10 tablets)

Dosage form Film bag tablets
Specifications Box of 10 blisters x 10 tablets
Ingredient Dextromethorphan
Indication Dry cough, cold
Contraindication Bronchial asthma, acute respiratory failure, chronic respiratory failure

Ingredient

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Composition information	Content
Dextromethorphan	15mg

Uses

Indications

Dexipharm drugs are indicated in the following cases:

Treatment of symptoms of throat and bronchial is irritated when the cold cold or when inhaling the stimulant.

ATC code: R05DA09.

dextromethorphan hydrobromid is a cough reduction drug that works on the brain cough center. Although the chemical structure is related to morphine, dextromethorphan has no pain to relieve pain and very little sedative effects.

dextromethorphan is used to reduce cough due to mild stimulation in the bronchial and throat as the usual cold or inhalation of stimulants. Dextromethorphan is most effective in treating chronic cough, no sputum. The drug is often used in combination with many other substances in the treatment of upper respiratory symptoms. The drug has no effect on phlegm.

The effect of dextromethorphan is equivalent to the effect of Codeine in the treatment of chronic cough but less side effects in the digestive tract. With the treatment dose, the anti -them of the drug lasts 5 - 6 hours. The drug has low toxicity but with very high doses can inhibit the central nervous system.

pharmacokinetic

dextromethorphan is quickly absorbed through the digestive tract and reaching the peak concentration in plasma after 2 - 2.5 hours. The drug works within 15 - 30 minutes after drinking, lasting about 6 - 8 hours.

dextromethorphan after absorption is widely distributed in the body. There is no sufficient information about the excretion of dextromethorphan in breast milk.

dextromethorphan is metabolized in the liver. The metabolism of the liver depends on the genetic properties. A number of drugs O - Demethyl turned into CYP2D6 enzyme into Dextrophan, is also a substance that reduces mild cough and is n - demethyl turned by enzyme CYP3A4/3A5 to 3 - methoxymorphinan, then this substance continues to be transformed into 3 - hydroxy - morphinan by enzyme cyp2d6.

dextromethorphan is excreted in urine in a constant form and Demethyl metabolites. Dextromethorphan's waste sale time in normal people is about 1.4 hours - 3.9 hours.

Before taking Dexipharm 15mg Imexpharm drugs for cough symptoms (10 blisters x 10 tablets)

How to use

Take oral use. Drink whole tablets with a little water.

Some special notes on drug treatment before and after using the drug:

There is no special requirement on drug treatment after use. Maximum: 120mg/24 hours.

Children 6 to 12 years old: 15mg, 6 - 8 hours/time. Maximum: 60mg/24 hours.

Children under 6 years old: Dextromethorphan content contained in Dexipharm 15 film tablets is not suitable for children under 6 years old.

Elderly: adult dose.

Patients are at risk of respiratory failure and patients who have coughing up phlegm, pus, maximum time to take the drug no more than 7 days.

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.

What to do when overdose?

How to handle: Support treatment, use Naloxon 2mg intravenously, for reiteration if a total dose is 10mg.

What to do when you forget the dose? However, if close to the next dose, skip the forgotten dose and take the next dose at the time as planned. Do not drink twice as prescribed.

Side Effects

When using Dexipharm, you may experience unwanted effects (ADR). Some side effects recorded in research on users of this drug are:

Common, ADR> 1/100

Body: Fatigue, dizziness.

The drug can cause drowsiness, avoiding use with central neurological and alcoholic inhibitors. In case of respiratory failure and inhibiting the central nervous system, using naloxon, a dose of 2 - 10mg, intravenous injection.

This is not a full portfolio of all side effects and may occur other side effects. If you encounter any unwanted effect, stop taking the medication and immediately notify your doctor or immediately go to the nearest medical facility for timely treatment.

Rare, ADR

Sometimes when you feel sleepy, digestive disorders.

Skin: urticaria.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

Contraindicated

Dexipharm drugs are contraindicated in the following cases:

Hypersensitivity to dextromethorphan or any ingredients of the drug. (SSRI).

Children under 2 years old.

Precautions when using drugs

Patients are at risk or respiratory decline.

Using dextromethorphan is related to histamine release, so be careful with children with allergies.

Abuse and dependence on dextromethorphan may occur (though rare), especially due to prolonged high doses.

Simultaneous use of dextromethorphan with neurological or alcohol inhibitors can increase the effect on central nervous systems and toxic at relatively small doses.

The starch starch in this drug contains gluten with very low content. Patients allergic to starch should not use this medication. Patients with Celiac disease need to take medicine very carefully.

The ability to drive and operate machinery

Some unwanted effects of the drug such as dizziness, slight drowsiness, tremor ... can reduce the ability to focus and react of the patient, so it should not be used when driving and operating machinery.

Pregnancy

Dextromethorphan is considered safe when used for pregnant women and is not at risk for fetuses. However, only use this drug when really necessary.

Do not use ethanol or products containing ethanol while using Dexipharm 15.

Breastfeeding period

Not enough information about the excretion of dextromethorphan into breast milk. Avoid using dextromethorphan combination preparations with ethanol for nursing mothers.

Medicinal interaction

Amiodaron, Haloperidol, Propafenon, Thioridazin, Quinidine and selective Serotonin Restrain Serotonin Inhibitors (SSRIs) CYP2D6 Enzyme inhibit the CYP2D6 enzyme. Therefore, these drugs reduce the metabolism of dextromethorphan in the liver, increasing serum concentration and increasing the ADR of dextromethorphan.

Avoid simultaneous use with imao drugs because it can cause harmful interaction reactions.

Simultaneously used with central neurological inhibitors can enhance the central neurological inhibitor of these drugs or of dextromethorphan.

Valdecobid increases the concentration of dextromethorphan in serum when used together. Simultaneous use of dextromethorphan with Linezolid causes Serotonin syndrome syndrome.

Memantin can increase both the frequency and unwanted effects of Memantin and Dextromethorphan, so avoid combining use. Do not use in combination with moclobemid.

Cavalry of the drug: Because there is no studies on the cavalry of the drug, does not mix this drug with other drugs.

Storage

You should store at room temperature, below 30 degrees Celsius, avoid moisture and avoid light. No storage in the bathroom or in the freezer.

You should remember that each drug may have different storage methods. Therefore, you should read carefully storage instructions on the packaging or ask the pharmacist.

Keep pills out of reach of children and pets.

Expiry date: 36 months from the date of manufacture.

Production facility: Imexpharm Pharmaceutical Joint Stock Company.

No. 04, 30/4 Street, Ward 01, Cao Lanh City, Dong Thap Province. Vietnam.

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