Dexlacyl 0.5mg khapharco treatment for rheumatism, collagen (500 tablets)

Dosage form Box of 500 capsules
Specifications Betamethasone
Ingredient Allergic rhinitis, bronchial asthma, rheumatoid arthritis

Ingredient

Composition information	Content
Betamethasone	0.5mg

Uses

Indications

Dexlacyl drugs are indicated in the following cases:

rheumatoid arthritis: rheumatoid arthritis, acute and semi -acute inflammation, convex inflammation, non -specific acute tendonitis, muscle inflammation, fibroid inflammation, tendonitis, psoriasis arthritis. Hegemony, atopic dermatitis, hypersensitivity reactions to drugs and insects. Mineralocorticoid), congenital adrenal hyperplasia, pus -festered thyroid inflammation and hypercalcemia due to cancer. lung. EM. Betamethasone has anti -inflammatory, anti -rheumatic and anti -allergic effects.

pharmacokinetic

absorption

betamethason is easily absorbed through the gastrointestinal tract and is also easily absorbed when used on the spot.

Distribution

betamethason quickly distributed into all tissues in the body. Drugs through the placenta and can be exported to the mother in small amounts.

Metabolism

betamethason metabolizes mainly in the liver but also in the kidney.

Elimination

betamethason excreted mainly into the urine.

Before taking Dexlacyl 0.5mg khapharco treatment for rheumatism, collagen (500 tablets)

How to use

Oral drugs.

Dosage

Sold -prescribed drugs, as directed by the physician.

Depending on the disease, the usual dose.

for adults

From 1 - 10 tablets/day.

for children

From 1 - 5 years old: from 1 - 4 capsules/day.

From 6 - 12 years old: from 1 - 8 capsules/day.

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.

What to do when overdose? Effects due to increased corticosteroids do not appear early unless high doses are continuous.

Symptoms

Systemic effects due to corticosteroid overdose include: Sodium and water holding effects, increased appetite, mobilizing calcium and phosphorus accompanied by osteoporosis, loss of nitrogen, hyperglycemia, reducing the effect of tissue regeneration, increasing sensory with bacterial infections, adrenal insect activity, mental disorders and neurological disorders.

Treatment

In case of an overdose, the electrolyte must be monitored with serum and urine. Pay special attention to sodium and potassium balance. In the case of chronic poisoning, stop the drug slowly. Treatment of electrolyte imbalance if needed.

What to do when you forget a dose? However, if close to the next dose, skip the forgotten dose and take the next dose at the time as planned. Note that it should not be used double the prescribed dose.

Side Effects

When using dexlacyl, you may experience unwanted effects (ADR).

Common

Metabolism: loss of potassium, sodium hold, water retention.

Endocrine: Menstrual periods, developing cushing syndrome, inhibiting fetal growth in the uterus and children, reducing glucose tolerance, revealing potential diabetes, increasing insulin demand or hypoglycemic drugs in diabetes.

muscle muscle: muscle weakness, loss of muscle mass, osteoporosis, skin atrophy and under the skin, aseptic abscess.

Less

Mental: refreshing, mood change, severe depression, insomnia.

Eye: glaucoma, opaque glass.

digestive: gastric ulcer and may then puncture and bleeding, pancreatitis, abdominal distention, esophageal ulcer.

Rare

Skin: Allergic dermatitis, urticaria, vasoconstriction.

nervous: Hurry increased intracranial pressure.

Other: Anaphylaxis or hypersensitivity reactions and decreased blood pressure or similar shock.

Instructions on how to handle ADR

Most of unwanted effects can often be recovered or reduced by reducing the dose, which is more preferred to use than stopping the drug.

Use oral corticosteroids with food, limit indigestion or digestive tract irritation. Patients with prolonged treatment with corticosteroids at the dose may have to limit the use of sodium and supplement potassium during treatment.

Because corticosteroids increase protein catabolism, it may be necessary to increase the protein diet during prolonged treatment. Using calcium and vitamin D can reduce the risk of osteoporosis caused by corticosteroids during prolonged treatment. People with a history or a risk factor for stomach ulcers must be taken care of by anti -ulcer drugs. Patients who are using glucocorticoids that have anemia need to think of the causes may be due to stomach bleeding.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

Contraindicated

Dexlacyl drugs are contraindicated in the following cases:

is contraindicated for corticosteroid therapy, especially for patients with diabetes, mental illness, stomach ulcers and duodenum, in bacterial infections and viral infections, in body fungal infections and in patients with overcurrent of betamethasone or with other corticosteroids or any ingredients in the preparation.

Caution when using

The lowest and lowest dose of corticosteroids can be used to control the treatment, when reducing the dose, gradually decreasing step by step.

When using the whole body corticosteroids must be very cautious in case of congestive heart failure, new myocardial infarction, hypertension, diabetes, epilepsy, glaucoma, thyroid defect, liver failure, osteoporosis, stomach ulcers, mental disorders and kidney failure. Children can easily increase the risk of some unwanted effects, in addition, corticosteroids can cause growth, the elderly also increases the risk of unwanted effects.

Progressive or potential tuberculosis is not used corticosteroids.

During the long -term corticosteroid therapy, regular monitoring of patients must be monitored.

may need to reduce sodium and add calcium and potassium.

The prolonged corticosteroid use can cause glass (especially in children), glaucoma with the ability to damage the optic nerve.

The ability to drive and operate machinery

No report.

Pregnancy

Use corticosteroids during pregnancy or people who are likely to consider the benefits and risks of the mother and embryo or fetus.

There was a weight loss in newborns when the mother was treated with long -term corticosteroids. Because of the ability to inhibit the adrenal shell in a newborn child because the mother has used long -term corticosteroids, when prescribing corticosteroids, it is necessary to consider the needs of the mother and the risk of the fetus. Short -term use of corticosteroids before birth, to prevent acute respiratory insufficiency syndrome, may not risk the fetus or newborn. Babies that mothers have used corticosteroid doses significantly during pregnancy must be carefully monitored about the signs of adrenal gland reduction.

breastfeeding period

Betamethason Exports into breast milk and may be harmful to children because the drug can inhibit development and cause other unwanted effects, so they should not be used for breastfeeding women.

Drug interaction

paracetamol

corticosteroids induce liver enzymes, which can increase to form a metabolic substance of toxic paracetamol to the liver. Therefore, an increased risk of liver toxicity if corticosteroid is used with high doses of paracetamol.

Triple antidepressants

These drugs do not reduce and may increase mental disorders caused by corticosteroids, do not use these antidepressants to treat the above -mentioned adverse effects.

Oral or insulin anti -diabetes drugs

Glucocortocoid may increase blood glucose, so it is possible to adjust the dose of one or both drugs when used simultaneously, may also need to adjust the dose of hypoglycemic drugs after stopping glucocorticoid.

glycosid digitalis

Concentrated with glucocorticoid may increase the possibility of arrhythmia or toxicity of Digitalis and lower potassium.

phenobarbiton, phenytoin, rifampicin or ephedrin

can increase the metabolism of corticosteroids and reduce their treatment effects.

Patients who use both corticosteroids and estrogen must be monitored on the excessive effect of corticosteroids because estrogen may change the metabolism and protein bonding level of glucocorticoid, leading to reduced waste, increasing half -life, increasing treatment and toxicity of glucocorticoid.

Use of corticosteroids with anticoagulants can increase or decrease anticoagulant effects, so it may be necessary to adjust the dose.

The coordination effect of nonsteroidal or alcoholic anti -inflammatory drugs with glucocorticoids can lead to increased occurrence or increased severity of the gastrointestinal ulcer. Corticosteroids may increase the concentration of salicylate in the blood. Must be cautious when used in combination with aspirin with corticosteroids in the case of reducing blood prothrombin.

Storage

In a cool dry place, avoid light. Under 30 ° C.

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