Dicellnase Farma Glow treat rheumatoid arthritis, osteoarthritis (6 blisters x 10 tablets)

Dosage form Box of 6 blisters x 10 tablets
Specifications Piroxicam
Ingredient Power post -injury, neuritis, gout, joint spondylitis, arthritis, rheumatoid arthritis

Ingredient

Composition information	Content
Piroxicam	20mg

Uses

Indications

Dicellnase 20 mg Farmalabor 6x10 is indicated in some diseases that require anti -inflammatory and/or analgesic diseases such as:

Rheumatoid arthritis and osteoarthritis (osteoarthritis).

A joint spine inflammation.

Pharmacy

Piroxicam is an nonsteroidal anti -inflammatory drug, Oxicam group, anti -inflammatory, analgesic and antipyretic effect. The general mechanism for the above effects may be due to Prostaglandin Synthetase inhibitors and thus prevents the formation of Prostaglandin, Thromboxan, and other products of Cycloxygenase enzymes. Piroxicam, also inhibit the activity of neutral polygon leukemia, even when there are cyclooxygenase products, so anti -inflammatory effects also include proteoglycanase and collagenase inhibitors in cartilage. Piroxicam does not work by stimulating the pituitary - adrenal axis. Piroxicam also inhibits platelet capacitors.

pharmacokinetics

Piroxicam is well absorbed through the gastrointestinal tract. Peak concentration in plasma appears from 3-5 hours after taking the drug. Food and anti -acid drugs do not change the speed and level of drug absorption. Because Piroxicam has a liver -intestinal cycle and has a lot of difference in absorption among patients, the sale time of the drug in plasma varies from 20 - 70 hours, this can explain why the effect of the drug is so different from patients, when using the same dose, this also means that the stable state of the drug is achieved after very different treatment time, from 4 - 13 days.

The drug is very strong with plasma proteins (99%minerals). The distribution volume is approximately 120 ml/kg. The concentration of drugs in plasma and in the epidemic is approximately equal when the drug state is stable (that is, after 7-12 days). Under 5% of urine excreted drugs in the form of unchanged. The main metabolism of the drug is hydroxyl - chemical pyridine, followed by glucuronic acid, then this complex is excreted in urine.

Before taking Dicellnase Farma Glow treat rheumatoid arthritis, osteoarthritis (6 blisters x 10 tablets)

How to use

Oral drugs.

Dosage

Adults: 20 mg, once a day.

Do not use more than 20 mg/day.

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.

What to do when overdose? Currently, due to the lack of experience in overdose, it is impossible to know the effectiveness and recommendations on specific detoxification effectiveness. However, gastric and supportive treatment measures should be applied. Drinking activated carbon can reduce the absorption and reabsorption of Piroxicam effectively, and thus reduces the remaining drug.

What to do when you forget a dose? However, if close to the next dose, skip the forgotten dose and take the next dose at the time as planned. Note that it should not be used double the prescribed dose.

Side Effects

When using Dicellnase 20 mg Farmalabor 6x10, you may experience unwanted effects (ADR).

Over 15% of Piroxicam users have some unwanted reactions, most of the digestive tract but many reactions do not hinder the treatment. About 5% must stop treatment.

Common, ADR> 1/100

Digestive: stomatitis, anorexia, epigastric pain, nausea, constipation, abdominal pain, diarrhea, indigestion.

Hematology: Hematitis and hematocrite, anemia, leukopenia, Eosin hypernagus. skin: itching, rash. nerve: dizziness, dizziness, drowsiness.

urinary tract: increased urea and blood creatinin.

Systemic: headache, discomfort.

Tinneton: tinnitus.

Cardiovascular, respiratory: edema.

Uncommon, 1/1000

Digestive: abnormal liver function, jaundice; hepatitis; Gastrointestinal bleeding, perforation and ulcers, dry mouth.

Hematology: thrombocytopenia, hemorrhagic dots, bruising, myeloma.

Skin: Sweating, Red rash, Stevens - Johnson syndrome.

nerve: depression, insomnia, restlessness, stimulation.

urinary tract: bleeding, protein - urinary, interstitial nephritis, damaged kidney syndrome. Systemic: Fever, symptoms like influenza.

The senses: swelling of the eyes, blurred vision, irritant eyes.

Cardiovascular, respiratory: Hypertension, congestive heart failure.

Rare, ADR

Digestive: pancreatitis.

Skin: Nail pepper, hair loss.

Neither nervous: restlessness, restless sitting, hallucinations, changing temperament, composition.

Urinary: urine. Body: Weakness.

Sensory: Temporary hearing.

Hematology: Hemolytic anemia.

Instructions on how to handle ADR

Notify the doctor the adverse effects encountered during the use of the drug.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

Contraindicated

Dicellnase 20 mg Farmalabor 6x10 contraindications in the following cases:

Hypersensitivity to piroxicam.

Stomach ulcer, acute duodenum ulcer.

History of bronchospasm, asthma, nasal polyps and quincke edema or jute due to Aspirin, or another nonsteroidal anti -inflammatory drug.

cirrhosis.

Severe heart failure.

People with many risks of bleeding.

Renal failure people with glomerular filtration level below 30 ml/min.

Precautions when using

Elderly.

Bleeding disorders, cardiovascular disease, a history of stomach -duodenal ulcer, liver failure or kidney failure.

People who are taking diuretics.

The ability to drive and operate machinery

Precautions when used for drivers and machinery operating because the drug can cause dizziness, dizziness.

Pregnancy

Like other Prostaglandin synthesis and release drugs, Piroxicam causes a risk of lung pressure in newborn babies, due to arteriosclerosis if these drugs are used in the last 3 months of pregnancy. Piroxicam also inhibits labor, prolongs pregnancy, and toxicity for the gastrointestinal tract in pregnant women. Do not use piroxicam for pregnant women in the last 3 months or near labor.

Breastfeeding period

Piroxicam excreted into breast milk. Not yet determined the safety of the drug used for mothers during breastfeeding. Do not recommend used for breastfeeding women.

Medicinal interaction

When using piroxicam simultaneously with cumarin anticoagulant drugs and high protein -linked drugs, it is necessary to monitor patients closely to adjust the dose of the drugs accordingly. Because of the high protein bond, Piroxicam can push other drugs from plasma proteins.

Do not treat the drug simultaneously with aspirin, because this will lower the plasma concentration of piroxicam (about 80% when treated with 3.9 g aspirin), and are not better than when only treated with aspirin, which increases unwanted effects.

When treating the drug simultaneously with lithium, it will increase lithium toxicity due to increasing lithium concentration in plasma, so it is necessary to closely monitor the concentration of lithium in plasma.

Use piroxicam simultaneously with antacidants that do not affect the concentration of piroxicam in plasma.

Storage

Store in closed boxes at temperatures below 30 ° C.

Other drugs

Disclaimer

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