Difflam anti -inflammatory tablets of raspberries Unique Pharma supports the treatment of tonsillitis, sore throat (1 blister x 8 tablets)

Dosage form Sucker
Specifications Box of 1 blister x 8 tablets
Ingredient Benzydamine Hydrochloride, Cetylpyridinium Chloride

Ingredient

Composition information	Content
Benzydamine hydrochloride	3mg
Cetylpyridinium chloride	1.33mg

Uses

Indications

Difflam anti -inflammatory bucket helps to temporarily reduce pain in the oral cavity including cases of tonsillitis, sore throat, radiation mucosal inflammation, mouth heat, mouth surgery and periodontal surgery, sore throat, swelling, redness and inflammation.

Pharmacokinus

Benzydamine is an anti -inflammatory irrelevant -related anti -inflammatory agent with a steroid group. Benzydamine is different from chemicals compared to other non -steroid anti -inflammatory substances in that benzydamine is base, not acidic form.

Research on experimental animals shows that, when using the whole body, Benzydamine works on pain and inflammatory edema. Benzydamin also inhibits grain creation. At local levels of treatment, Benzydamine has a local anesthetic effect. Benzydamine does not wear the mucus of the stomach mucosa when used for oral mice at a dose of up to 100 mg/kg.

Benzydamine's pain relief effect is shown on the model of experimental inflammation more clearly on inflammatory pain. Like aspirin drugs, Benzydamine also has an antipyretic effect. Peripheral reflexes inhibited fleeting after intravenous injection in cats.

Isomalt is an alternative line. It is a Disaccharide and is a mixture of the volume between glucose-mannitol and glucose-sorbitol. Isomalt does not change the amount of sugar measured in the blood.

Dynamic pharmacokinetics

The anti-inflammatory mechanism of Benzydamine is not related to the stimulation of the pituitary-edge of the adrenal. Like other non -steroid anti -inflammatory agents, Benzydamine inhibits prostagladin biosynthesis under certain conditions, but the characteristics of Benzydamine are not completely clarified. The stable effect of cell membranes can also be a mechanism of action of benzydamine.

absorption

Benzydamin absorbs well by oral. After local use, benzydamine hydrochloride in the form of solution, benzydamine is well absorbed through the mucous membrane of the inflammation where the anti -inflammatory and local anesthetic requires. After taking the drug, Benzydamine concentration in plasma is low and corresponds to the actual amount of swallow.

Excretion

Benzydamine and its metabolites are excreted mainly in urine. Metabolic drugs in the oxidation path are mainly, although it is observed with alkylation reduction.

It is possible to detect Benzydamine both in the blood and urine after gargling with a solution. Most of the absorption dose is eliminated within the first 24 hours. Treatment repeated within 7 days also does not cause cumulative benzydamine in plasma.

Before taking Difflam anti -inflammatory tablets of raspberries Unique Pharma supports the treatment of tonsillitis, sore throat (1 blister x 8 tablets)

How to use

Do not chew the difflam tablet but just leave the pills slowly in the mouth.

Dosage

Slowly suck on each tablet until it is dissolved, each tablet is 1 to 2 hours apart and maximum no more than 12 capsules/day.

No continuous treatment for more than 7 days.

Use medication for patients with renal failure

benzydamine and metabolites are eliminated through urine. Therefore, be careful about the risk of systemic effects in patients with severe renal failure.

Use drugs for patients with liver failure

Benzydamin is absorbed mainly in the liver. Therefore, be careful about the risk of a systemic effect in patients with severe liver failure.

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.What to do when overdose? The effects on the central nervous system have been reported after using high doses of Benzydamine hydrochloride. There is no specific antidote to Benzydamine. If you miss a large amount of drugs, symptomatic treatment.

When taking a large amount of drugs containing Isomalt may have a laxative effect.

In an emergency, call the 115 emergency center immediately or go to the nearest local health station.

What to do when you forget 1 dose? However, if the time to relax with the next dose is too short, skip the dose and continue the calendar of the drug. Do not use double dose to compensate for missed dose.

Side Effects

In general, the difflam preparations used on the spot in the mouth are well tolerated and the side effects are usually mild. The following side effects are reported after using preparations containing benzydamine hydrochloride in the form of solution.

Side effects:

The most commonly reported side effects are numbness (2.6%). Sometimes it may appear burning or aches at 1.4% of the treatment cases. Other side effects are less common, including the feeling of dry mouth or thirst (O, 2%of the treatment), itching (O, 2%), the feeling of heat in the mouth and changing the taste (

Systemic side effects:

Rarely sides of the whole body side effects. If so, mainly effects such as nausea, vomiting, digestive disorders (0.4%of treatment cases), dizziness (0.1%), headache and drowsiness ( Notify the physician the unwanted effects when using the drug.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

Contraindicated

anti -inflammatory difflam contraindications in the following cases:

Contraindicated for patients with a history of allergies to Benzydamine or Cetylpyridinium chloride or any ingredients of the drug.

Be cautious when used

If the sore throat is infected or superinfected, should consider treating according to the appropriate antibiotic regimen along with the use of anti -inflammatory tablets. Clinical effects in reducing the severity and the time of throat infection of the antibacterial component in the lozenges have not been set up.

When taking a large amount of drugs containing Isomalt may have a laxative effect.

Use drugs for young children:

Due to the lack of adequate clinical research data, it is not recommended for the use of drugs for children under 6 years old.

Use drugs for women during pregnancy and lactation

Classification for drugs for pregnant women: B2 group

Studies conducted on experimental animals are still incomplete or missing, but based on existing data, do not observe any evidence of increasing the risk of damage to the safety of Benzydamine hydrochloride has not been set for pregnant and lactating women. It is necessary to consider the risk ratio compared to the benefits that can be encountered when using anti -inflammatory tablets for these objects.

The effect of the drug on driving and operating machinery

There is no evidence of the effect of the drug on the ability to drive and operate machinery.

Drug interaction

There has not been an interaction of benzydamin hydrochloride and cetylpyridinium chloride with other drugs.

Storage

Leave a cool place, avoid light, temperature below 30⁰C.

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