Dimenhydrinat 50mg Traphaco anti -vomiting, anti -motion sickness (10 blisters x 10 tablets)
Dosage form Tablet
Specifications Box of 10 blisters x 10 tablets
Ingredient Dimenhydrinat
Indication Vomiting/nausea, motion sickness
Ingredient
| Composition information | Content |
| Dimenhydrinat | 50mg |
Uses
Indications
Dimenhydrinat 50mg drug is indicated in the following cases:
Dimenhydrinat absorbs well after drinking or injecting. The anti -vomiting effect usually starts immediately after intravenous injection, within 15 - 30 minutes after drinking, 30-45 minutes after the rectum and 20-30 minutes after the intramuscular injection. Time works from 3 to 6 hours after taking the drug. There is little information about the distribution and metabolism of dimenhydrinat. Like other antihistamine drugs, the drug can be widely distributed into the functions of the body, through the placenta, metabolized in the liver and eliminated through the urine. A small amount of dimenhydrinat is distributed into milk.
Pharmacokology
Dimenhydrinat is mainly used as a backup (more effective), anti -vomiting when motion sickness and anti -dizziness. The mechanism of these effects is unknown, but it may be related to Dimenhydrinat that reduces vestibular stimulation, the first impact on the earcings and when using high doses, the semicircular tubes of the inner ear.
The anti -vomiting effect can also be due to the chemical trigger trigger zone. Some researchers suggest that dimenhydrinat inhibits acetylcholin is the main mechanism of action, because stimulating acetylcholin in the vestibular system and mesh may be the cause of nausea and vomiting due to motion sickness.
The central nervous system inhibitors often decrease after a few days of treatment and the anti -vomiting effect can be partially reduced after prolonged use. Dimenhydrinat is an antihistamine, but has not been evaluated for anti -allergy effects
Mechanism of action:
Dimenhydrinat is a first -generation H1 antihistamine, belonging to ethanolamine derivative group that causes strong sleep and Muscarin resistance. The drug works by competing with histamine in H1 receptors. In addition to antihistamine, Dimenhydrinat also has anti -cholinergic effects, anti -vomiting and sedative effects.
pharmacokinetic
dimenhydrinat absorbs well after oral or injection. The anti -vomiting effect usually starts immediately after intravenous injection, within 15-30 minutes after drinking, 30-45 minutes after the rectum and 20-30 minutes of intramuscular injection.
Time works from 3 to 6 hours after taking the drug. There is little information about the distribution and metabolism of dimenhydrinat. Like other antihistamine drugs, the drug can be widely distributed into the functions of the body, through the placenta, metabolized in the liver and eliminated through the urine. A small amount of dimenhydrinat is distributed into milk.
Before taking Dimenhydrinat 50mg Traphaco anti -vomiting, anti -motion sickness (10 blisters x 10 tablets)
How to use
Take the dimenhydrinat tablet 50mg with a full glass of water.
Dosage
Treplet sickness room, the first dose must take 30 minutes before departure.
Adults and children over 12 years: 1 - 2 capsules/time (50 -100mg), 4-6 hours/time when needed, (no more than 8 tablets/day).
Children 6 - 12 years old: Use 1/2 -1 capsules/time (25 - 50mg), 6-8 hours/time when needed (no more than 3 tablets/day).
Children 2 - 6 years old: use 1/4 - 1/2 tablets/time (12.5 - 25mg), 6-8 hours/time when needed (no more than 1.5 tablets/day).
Symptomatic treatment of menie: Take 25-50mg each time (1/2-1 tablets) 3 times a day for maintenance treatment.
Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.
What to do when overdose? Difficult to swallow, mental disorder cannot be distinguished from Atropine poisoning.
Treatment: There is no specific antidote when overdosing with antihistamines, only symptomatic and supportive treatment.
In an emergency, call the 115 emergency center immediately or go to the nearest local health station.
What to do when forgetting a dose? However, if the time to relax with the next dose is too short, skip the dose and continue the calendar of the drug. Do not use double dose to compensate for missed dose.
Side Effects
When using Dimenhydrinat 50mg, you may experience unwanted effects (ADR).
Sleep is the most common side effect of Dimenhydrinat. Some of the unwanted effects of Dimenhydrine are related to the anti -cholinergic effect of the drug.Common
Warnings
Before using Dimenhydrinat 50mg, you need to read the user manual carefully and refer to the information below.
Contraindicated
Dimenhydrinat 50mg contraindications in the following cases:
urinary retention related to the disease in the urethra - prostate.
Precautions when using
Caution when taking drugs for drivers or operating machinery because Dimenhydrinat has the effect of drowsiness, reducing alertness.
Avoid drinking alcohol or using other central neurological inhibitors when using dimenhydrinat because it increases the effect of drowsiness.
Due to the anti -cholinergic effect of the drug, it is necessary to consider carefully when using the drug for chronic constipation (risk of intestinal paralysis), bladder obstruction, prostate hypertrophy because of the risk of worse condition.
Dimenhydrinat's anti -vomiting effect can hinder the diagnosis of appendicitis and cover signs of toxicity when overdose of other drugs.
Dimenhydrinat can cover the toxic symptom with hearing, so it is necessary to closely monitor when used with special drugs that are toxic to hearing.
Be cautious when taking medicine for the elderly because it is prone to hypotension, dizziness, nausea.
The ability to drive and operate machines
Dimenhydrinat 50mg drug causes drowsiness so it is not used when driving and operating machinery.
Pregnancy and lactation
There has been no full research on the use of Dimenhydrinat drugs in pregnant women. Studies conducted on humans and animals do not see an increase in the abnormal risk of pregnancy due to dimenhydrinat. However, only Dimenhydrinat should only be used during pregnancy when really necessary.
The drug inhibits milk secretion due to the anti -cholinergic effect, a small amount of dimenhydrinat distributed in breast milk is at risk of harmful effects on the baby. Therefore, it is necessary to consider stopping the drug or stop breastfeeding when taking the drug.
Drug interaction
dimenhydrinat increases the effects of central neurological inhibitors such as alcohol and barbiturates. If Dimenhydrinat is used with central neurological inhibitors, be careful to avoid overdose.
The drug increases the effects of anti -cholinergic drugs.
When concurrent with aminoglycosides or other ear poisonous pills, Dimenhydrinat can cover the early symptoms of toxicity to hearing.Storage
Leave a cool place, avoid light, temperature below 30⁰C.
To be out of reach of children.
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