Donepezil ODT 10 Savi Treatment of symptoms and temporarily reduced intellectual decline (3 blisters x 10 tablets)

Dosage form Box of 3 blisters x 10 tablets
Specifications Donepezil HCl

Ingredient

Composition information	Content
Donepezil HCl	10mg

Uses

indications

Donepezil 10 drugs are indicated in the following cases:

Indications for symptomatic treatment and temporary reduction of mild, moderate and severe dementia in Alzheimer's disease. have benefits in therapy.

Dynamic pharmacokinetics

The highest concentration in plasma reaches about 3 to 4 hours after drinking. The selling time at the end of about 70 hours, so the only daily dose will gradually lead to a stable state. Food does not affect the absorption of the drug. About 95% Donepezil is attached to human plasma proteins. Donepezil distribution in different tissues has not been clearly studied. Donepezil is partially metabolized through isenzyme CYP3A4 and with less than CYP2D6 into 4 major metabolites. Donepezil is eliminated in urine in both forms of unchanged and metabolic forms. The sale time is about 70 hours.

Before taking Donepezil ODT 10 Savi Treatment of symptoms and temporarily reduced intellectual decline (3 blisters x 10 tablets)

How to use

Use the drug in accordance with the instructions of the doctor or pharmacist. Take oral, drink in the evening, before going to bed. The time of oral oral regarding depends on the meal for the dose of 5 mg/day, it is possible to break the tablet in half of the tablet.

Dosage

Adults and the elderly

Initial dose: 5 mg/day (1 -day dose per day). After 1 month, the doctor may increase to a dose of 10 mg/day (1 -dose per day).

Dosage may vary depending on the time of medication and doctor's appointment. The maximum daily dose proposed is 10 mg.

Patients must not arbitrarily change the dose or stop using the drug without a doctor's prescription. When stopped using, the effectiveness will slowly decrease.

The doctor will advise the patient to continue taking the drug for how long. Patients need a doctor regularly to be commented on the treatment and evaluation of symptoms.

People with kidney failure and liver failure

Notify your doctor if you have liver or kidney disease. Donepezil can be used for patients with renal failure or mild to moderate liver failure. Patients with severe liver failure should not use Donepezil.

Children

Not recommended for children under 18 years old.

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.

What to do when overdose?

What to do when you forget 1 dose? However, if the time to relax with the next dose is too short, skip the dose and continue the calendar of the drug. Do not use double dose to compensate for missed dose.

Side Effects

When using Donepezil 10, you may experience unwanted effects (ADR).

Very common, common, ADR> 1/100

Digestive: diarrhea, nausea, abdominal discomfort.

Neurological: fainting, dizziness, headache, difficulty sleeping (insomnia), hallucinations, abnormal dreams including nightmares, agitation, aggressive behaviors.

immune and allergies: rash, itching.

Systemic: fatigue, anorexia, pain, accidents (patients can easily fall).

Less, rare, ADR

Cardiovascular: Slow heart rate.

Digestive: Increasing salivation.

Bone muscles: hard, tremor, losing movement control, especially moving on the face, tongue and limbs.

Instructions on how to handle ADR

When experiencing side effects of the drug, it is necessary to stop using and notify the doctor or go to the nearest medical facility for timely treatment.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

contraindicated

Savi Donepezil 10 Savipharm 10x3 contraindicated in the following cases:

Hypersensitivity to Donepezil hydrochloride, piperidin derivatives or any ingredients of the drug.

Caution when using

Need to notify the doctor if the patient suffers from the following conditions before taking the drug: stomach or duodenal ulcer, epilepsy or convulsions, heart disease (disorders or slow heart rate), asthma or other chronic lung disease, liver or hepatitis, difficulty urinating or mild kidney failure. The excipient component contains lactose. Patients have rare genetic problems such as galactose intolerance, lactase deficiency or Glucose-Galactose should not use this product.

The ability to drive and operate machinery

Alzheimer's disease can reduce driving or operating machinery. Do not drive or operate machines unless there is a doctor's safety assessment.

Donepezil can cause fatigue, dizziness and cramps in the muscle. If you experience the above symptoms, do not drive or operate machines.

Pregnancy

Notice to the doctor if you are pregnant, suspected of being pregnant or intended to get pregnant before using the drug.

Breastfeeding period

Should not be used for breastfeeding women.

Drug interaction

Donepezil can affect or be affected by the following drugs:

Other drugs to treat Alzheimer's disease, for example Galantamin. erythromycin, rifampicin. Atenolol).

If the patient is anesthetized to prepare for surgery, it is necessary to notify the anesthetic doctor and anesthetic technician that is treating Donepezil because it affects the amount of anesthetic needed.

Do not take alcohol while taking the drug because alcohol can change the effect of the drug.

Storage

in a dry place, the temperature does not exceed 30 ° C, avoiding light.

Other drugs

Disclaimer

Every effort has been made to ensure that the information provided by Drugslib.com is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Drugslib.com information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Drugslib.com does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Drugslib.com's drug information does not endorse drugs, diagnose patients or recommend therapy. Drugslib.com's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners.

The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Drugslib.com does not assume any responsibility for any aspect of healthcare administered with the aid of information Drugslib.com provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.