Dorithricin Hyphens suckers treat symptoms of mouth and throat infections (20 tablets)

Dosage form Sucker
Specifications Box of 2 blisters x 10 tablets
Ingredient Tyrothricin, benzalkonium, benzocaine
Indication Sore throat

Ingredient

Thành phần cho 1 viên

Composition information	Content
Tyrothricin	0.5mg
Benzalkonium	1mg
Benzocaine	1.5mg

Uses

Indications

Dorithricin drugs are indicated for use in cases of treating symptoms of mouth -throat infections such as sore throat, difficulty swallowing.

Pharmacokology

Pharmacological Group of Treatment: Thraxis drugs

ATC code: R02AA02

In -spot antibiotics tyrothricin are a peptide mixture of 80% tyrocidin and 20% gramicidin. Gram -positive bacterial anti -bacterial activity, especially two species of streptococci and staphylococci related to mouth and pharyngeal infections, based on two different mechanisms of action: Tyrocidin starts on the transportation of nutrients through bacterial cell membranes, leading to a phenomenon Fruit inhibits the phosphorylation of the respiratory chain that leads to the metabolism of the bacteria to stop. Because the impact on this cell membrane is not specific, there is no cross -resistance to other antibiotics when using tyrothricin on the spot. Tyrothricin on the spot promote granular and epithelial process.

Benzalkonium Chlorid is a mixture of four -level ammonium compounds with strong surface activity with wide antibacterial spectrum, including gram -positive bacteria and gram -negative bacteria. Due to the structural long water chain in the structure, the benzalkonium chlorid is capable of attaching to the cytoplasmic membrane that inhibits the growth and prize of the bacteria. When used on the spot, benzalkonium chloride is well tolerated and does not cause cross -resistance to other antibiotics.

benzocaine is an oil ester (ethyl ester of para acid - aminobenzoic acid), which has a fast starting effect thanks to high affinity with membrane structure. The ion exchange process is inactivated by the replacement in the structure of the nerve cell membrane, resulting in the prevention of the cellular reduction process and clogging nerve impulses, having fast pain relief.

When used as directed, dorithricin lip helps treat topical antibacterial in cases of stomatitis and sore throat because the active ingredients enter the inflammatory organizations in the mucosa and stay for a long time. The drug relieves fast pain due to the surface anesthetic effect of benzocaine. The combination of tyrothricin - specific antibiotics that inhibit bacteria and antiseptic localities with benzalkonium chlorid - have antiseptic effects, as highly effective drugs for most bacteria, destroy the main pathogens.

Dorithricin lozenges are well tolerated, help restore mucosa and heal wounds.

Dynamic pharmacy

tyrothricin: tyrothricin is not absorbed.

benzalkonium chloride is only absorbed in a small part and is quickly decomposed by the liver and kidneys.

Benzocaine is only absorbed in a small amount due to the low soluble properties in water and hydrolyzed into para-aminobenzoic acid. There is currently no other meaningful data on the pharmacokinetics of Benzocaine.

Before taking Dorithricin Hyphens suckers treat symptoms of mouth and throat infections (20 tablets)

How to use

Suck to slowly dissolve the pills in the mouth.

Dosage

suck 1 - 2 capsules/time, can be used several times a day, each time about 2-3 hours apart. It is necessary to continue treating another day after the symptoms are gone.

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.

What to do when overdose?

Symptoms of gastrointestinal tract and blood methemoglobin formation (especially in children) may occur after being swallowed a large amount of tablets.

In this case, methods that reduce absorption (use activated carbon, gastric lavage), if possible, anti -methemoglobin measures need to be used.

What to do when forgetting a dose? However, if close to the next dose, skip the forgotten dose and take the next dose at the time as planned. Do not drink twice as prescribed.

Side Effects

When using dorithricin, you may experience unwanted effects (ADR).

Rare, 1/10000 ≤ ADR

Skin allergic reaction, namely with the ester of Para acid - Aminobenzoic (benzocaine), has been reported in some rare cases. Some cases of blood methemoglobin occur when using benzocaine on the spot, especially in children or when exposed to open open wounds.

Unknown frequency

In sensitive patients, there may be sensitivity to substances with para groups (penicillin sulphonamid, sunscreen cosmetics, acid P - Aminosalicylic).

When experiencing side effects of the drug, it is necessary to stop using and notify the doctor or go to the nearest medical facility for timely treatment.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

Contraindicated

Dorithricin drugs contraindicated in the following cases:

Hypersensitivity to any ingredients of the drug.

Caution when using

For all cases of patients with pus tonsillitis, the doctor should decide in addition to the use of basic medications needed such as systemic antibiotics, whether patients use dorithricin tablets or not.

Patients with severe sore throat or sore throat with high fever, headache, nausea, vomiting, should not use dorithricin lozenges for more than 2 days without advice of medical staff.

Patients who tend to be prone to skin allergies (eczema) are at risk of drug sensitivity.

Patients with diabetes: Sorbitol amount instead of sugar for 1 dorithric suck is equivalent to about 0.07 sparks.

Because the drug does not guarantee babies and young children know how to use the drug properly (how to keep the drug), dorithricin tablets are not suitable for these ages. Use only tablets for children if children know how to keep the medicine properly.

The ability to drive and operate machinery

Dorithricin lozenges do not have or negatively affect the ability to drive and operate machinery.

Pregnancy

There is no data on using dorithricin in pregnant women. For active ingredients benzalkonium chloride, mice studies show some reproductive toxicity, but only when used in extremely high doses (50 - 200 mg/kg of weight). Due to the very high dosage use and special lines in this study, there is no evidence that these findings have any clinical relevance when using dorithricin on humans. For tyrothricin and benzocaine, animal studies on reproductive toxicity are not enough.

So far, studies on pregnant or breastfeeding women are incomplete, because common recommendations, only dorithricin should be used for pregnant or lactating women when the doctor is consulted and considered if the benefits are superior to the risk of fetus or infant/child.

Breastfeeding period

Predict that there is no effect on infants/breastfeeding babies because of the level of body absorption of nursing women for tyrothricin, benzalkonium chloride and benzocaine are negligible.

Unknown tyrothricin, benzalkonium chloride and benzocaine are secreted into breast milk or not, but at dorithricin's treatment dose, predict that there is no effect on infant/breastfed babies.

Drug interaction

There is no known interaction.

Storage

Storage below 30 ° C.

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