Drinking Siro Drink Drenoxol Laboratorios Treatment of respiratory disease, bronchitis, bronchial asthma (4 blisters x 5 tubes)

Dosage form Syrup
Specifications Box of 4 blisters x 5 tubes
Ingredient Ambroxol hydrochloride

Ingredient

Composition information	Content
Ambroxol hydrochloride	30mg

Uses

indication

Siro oral Drenoxol indicated treatment in the following cases:

Acute and chronic diseases of the respiratory tract are associated with the abnormal secretion of bronchi and impaired transportation, especially chronic bronchitis, asthma bronchitis and bronchial asthma.

ATC code: R05cb06.

Ambroxol Hydrochloride is a derivative of bromhexine, a sputum soluble. The drug stimulates the mucus to secret out, and cut off the glycoprotein acid system in the mucus, causing the mucus to be less sticky.

Ambroxol Hydrochloride helps stimulate mucus to work and increase the cleaning ability of mucus, making sputum sputum easier.

Dynamic pharmacokinetics

Ambroxol is absorbed quickly and almost completely after drinking and reaching the maximum concentration in plasma for 1 to 3 hours.

Absolutely reduced birth by about 1/3 after drinking, due to the first metabolism through the liver. Ambroxol diffuses rapidly from blood to tissue and reaches the highest concentration in the lungs. The drug is associated with plasma protein about 85% and the sale time of the drug in plasma is from 7 to 12 hours.

Ambroxol is metabolized mainly in the liver. Metabolic products of the drug (for example, dibromoanthranilic acid and glucuronid complexes) are excreted mainly through the kidneys (~ 90%). Under 10% of the drug is eliminated through the kidneys in non -metabolic form.

The drug is slowly eliminated through the separation or enforced urination because the ambroxol is strongly attached to the tissue protein, the drug has a large integral and re -distributed volume from tissue to small blood.

In case of severe liver failure, the excretion of Ambroxol decreases from 20 to 40%.

In patients with severe renal impairment, the sale time of the metabolites of ambroxol prolonged.

Ambroxol through the brain and placenta barriers, the drug is also found in breast milk.

Before taking Drinking Siro Drink Drenoxol Laboratorios Treatment of respiratory disease, bronchitis, bronchial asthma (4 blisters x 5 tubes)

How to use

Drenoxol drugs in the form of oral orally, no injection.

Dosage

children

Dosage for children under 2 years of age: Use as directed by the doctor. Only use when medical supervision.

Dosage for children 2-5 years: 5 ml/time (½ tube), x2 times/day (corresponding to 30 mgambroxol hydrochloride/day).

Dosage for children 5 - 12 years: 5 ml/time (½ tube), 2-3 times/day (corresponding to 30 - 45 mg ambroxol hydrochloride/day).

Adults

Adults and teenagers over 12 years old:

In the first 2-3 days: 10 ml/time (1 tube), 3 times/day (corresponding to 90 mg of ambroxol hydrochloride/day). However, patients should not use without the advice of a doctor.

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.What to do when using overdose?

What to do when you forget 1 dose? However, if the time to relax with the next dose is too short, skip the dose and continue the calendar of the drug. Do not use double dose to compensate for missed dose.

Side Effects

Unwanted effects (ADR) when using Drenoxol Silo that you may encounter:

Common (ADR> 1/100)

Digestive: There may be heartburn, indigestion, sometimes nausea, vomiting.

allergies, mainly rash.

Rare (ADR Dry mouth and increase transaminase.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

Contraindicated

Siro oral Drenoxol is contraindicated in the following cases:

Patients with a history of allergies to Ambroxol or with any other ingredient of the drug.

Caution when using

should be very careful in the following cases:

The use of a mucus or sputum can lead to a decrease in mucus and increase the output of phlegm through the activity of the microflora layer of the respiratory tract or cough reflex. In case they have phlegm, should increase the output of phlegm through sputum and cough.

Need to be very cautious when taking drugs for patients in the following cases:

Patients with asthma and/or severe respiratory disease and weak patients, because the cough reflexes are weaker, there is a risk of airway obstruction, which is the result of increasing the amount of sputum is excreted and cannot be exposed. Sorbitol's absorption. If you have a problem with some sugar tolerances, you should consult your doctor before taking this medication. Therefore, it is possible to consider reducing the dose of drugs in these objects.

Using drugs for women during pregnancy and lactation

Women during pregnancy should use Drenoxol?

Although animal studies show that the drug does not cause teratogenicity, it is also recommended that Drenoxol should not be used in the first three months of pregnancy.

Follow the instructions from the doctor. The drug should only be used when the benefits are out of risks.

Should breastfeeding women take Drenoxol?

Ambroxol passes through the placenta and secretes into breast milk. Due to the lack of studies on the use of ambroxol during pregnancy and during breastfeeding, thus should only use Drenoxol after cautious consideration between the benefits of treatment and possible risks.

The effect of the drug on the ability to drive and operate machinery

who often drive or operate machinery should take Drenoxol?

In normal concentrations, Drenoxol does not limit the ability to drive or operate machinery.

Drug interaction

drug interactions can affect the activity of the drug or cause side effects.

Use ambroxol with some antibiotics (amoxicillin, cefuroxim, erythromycin, DoxycyCline) can lead to an increase in antibiotic concentration in lung tissue.

Do not combine ambroxol with a anti -cough drug (e.g. codeine) or a sputum drying (e.g. atropine): unreasonable coordination

Patients should notify the doctor or pharmacist a list of the drugs and functional foods you are using. Do not use or increase or decrease the dose of the drug without the guidance of a doctor.

Storage

Leave a cool place, avoid light, temperature below 30⁰C.

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