Drugs used in addition to Comozol Cream Daehwa to treat skin fungal infections, candidiasis (10g)

Dosage form Box
Specifications Ketoconazole
Ingredient Fungal mushrooms, oily dermatitis, contact dermatitis, nail mushrooms

Ingredient

Composition information	Content
Ketoconazole	20mg/g

Uses

Indications

Comozol drugs are indicated in the following cases:

Treatment of skin fungal infections such as body fungus, thigh skin fungus, hand fungus hand and fungus of legs caused by Trichophyton spp, microsporon spp and epidermophyton spp. out.

Normally Ketoconazole cream has a quick effect on itching, common symptoms in skin fungal diseases and yeast infections, as well as when infected with Malassezia spp. This symptom improvement is recorded before observing the first signs of healing.

Ketoconazole - an imposer dioxolane derivative, has a strong antifungal activity for leather fungus such as Trichophyton spp., Epidermophyton Flocosum and Microsporum spp. And yeast, including Malassezia spp. and Candida spp. The effect of the drug on Malassezia spp. is particularly clear.

A study in 250 patients has shown to apply twice a day for 7 days with 2% ketoconazole cream and 1% clotrimazole cream for 4 weeks in both legs that have proven to be effective in patients with fungal skin fungus (athletes' legs that are damaged between the toes. The first effect is the result of a negative test of KOH with a microscope after 4 weeks. Treatment with Ketoconazole 2% cream shows the equivalent effect with 1% Clotrimazole cream for 4 weeks. There is no evidence of recurrence after treatment with ketoconazole at 8 weeks.

pharmacokinetics

Ketoconazole concentration in plasma is not detected after applying ketoconazole cream in adults. In a study in children with seborrheic dermatitis (n = 19), about 40 g of ketoconazole cream has been applied to the skin daily over 40% of the body surface area, the concentration of ketoconazole in plasma has been found in 5 children, with a concentration of 32-133 ng/ml.

Before taking Drugs used in addition to Comozol Cream Daehwa to treat skin fungal infections, candidiasis (10g)

How to use

Apply skin.

Dosage

Adults

Fungal fungal disease

Apply Comozol in the affected skin 2 times daily. The usual treatment time for mild fungal diseases is 1 week. Treatment of fungal infections in a wider or worse range (for example, the soles of the foot or sides of the foot) should be continued until several days after all the signs and symptoms to prevent recurrence.

For other fungal diseases

Apply Comozol at the affected skin once or twice a day, depending on the severity of the disease.

Need to continue treatment until a few days after all the signs and symptoms of the disease.

The usual treatment period is: 2-3 weeks for tinea versicolor for 3-4 weeks for body fungus.

Review diagnosis if clinical symptoms are not improved after 4 weeks of treatment.

Systemic hygiene measures should be taken to control the source of infection or re -infection.

Seborrheic dermatitis is a chronic and high recurrence.

Children

The data on the use of 2% ketoconazole for children is limited. Do not use comozol for children

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.

What to do when overdose?

Applying the recommended overdose can cause erythema, edema and burning sensation, and will disappear after treatment.

Cases of swallowing drugs

If you accidentally swallow the medicine, you need to apply the measures to support and treat million.

What to do when you forget a dose? However, if close to the next dose, skip the forgotten dose and take the next dose at the time as planned. Note that it should not be used double the prescribed dose.

Side Effects

When using Comozol, you may experience unwanted effects (ADR).

The safety of Ketoconazole cream is rated over 1079 patients participating in 30 clinical trials. Ketoconazole cream is applied to the skin in the infected area. Based on the safety data obtained from clinical trials, the most common unwanted effects have been reported (at a ratio of> 1%) is (with percentage): itching at the topical position (2%), skin burning sensation (1.9%), and the erythema at the topical position (1%).

includes the above unwanted effects, the table below presents the unwanted effects that have been reported when using ketoconazole cream from clinical trials or after -sales experience. The frequency of occurrence is indicated according to the following convention:

common (≥1/10)

Common (≥1/100 to

Less (≥ 1/1000 to

Rare (≥1/10,000 to

Very rare (

Do not know the frequency (not estimated from the existing clinical test data).

Classification of organs

Unwanted effects

Common

(≥1/100 to

Less

(≥1/1,000 to

Unknown frequency

Skin burning sensation

Puffiness

Contact dermatitis

rash

Peeling skin

sticky skin

urticaria

The erythema at the topical position
itching at the topical position

bleeding at an uncomfortable
position at the topical site of dry skin
at the top of the inflammatory
position at the topical site of irritating drugs at the topical
at the position

When experiencing side effects of the drug, it is necessary to stop using and notify the doctor or go to the nearest medical facility for timely treatment.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

Contraindicated

Comozol medicine is contraindicated in cases where patients have a history of hypersensitivity to ketoconazole or any component of the drug.

Precautions when used

If used simultaneously with topical corticosteroids, to prevent the reverse reaction after long-lasting treatment with topical corticosteroids should continue to apply a small amount of corticosteroids in the morning and apply Comozol in the evening, then slowly stop the corticosteroid treatment for a period of 2-3 weeks.

Comozol cream contains propylene glycol, so it can cause skin irritation.

Comozol cream contains cetanol and stearyl alcohol, so it can cause local reactions on the skin (for example, contact dermatitis).

The ability to drive and operate machinery

There is no evidence that this drug affects the ability to drive and operate machinery.

Pregnancy

There is no adequate and controlled study in pregnant women. Data on a limited number of pregnant women exposed to drugs shows that there is no side effects of Ketoconazole on the spot to pregnant women or the health of the fetus/infant. Animal studies have shown reproductive toxicity at non -related doses of ketoconazole.

There is no ketoconazole in plasma concentration after applying a comozol cream on the skin of an unpopular woman's skin. There is no known risk when using comozol cream in pregnant women.

Only use drugs for pregnant women when the benefits of drug use are superior to possible risks.

Breastfeeding period

There is no adequate and controlled study in breastfeeding women. There is no known risk when using comozol cream in nursing women.

Only use drugs for breastfeeding women when the benefits of using drugs are superior to the risk.

Drug interaction

There are no studies on drug interactions conducted.

Storage

Storage in closed packaging, at temperatures below 30 ° C.

Other drugs

Disclaimer

Every effort has been made to ensure that the information provided by Drugslib.com is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Drugslib.com information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Drugslib.com does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Drugslib.com's drug information does not endorse drugs, diagnose patients or recommend therapy. Drugslib.com's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners.

The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Drugslib.com does not assume any responsibility for any aspect of healthcare administered with the aid of information Drugslib.com provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.