Drugs used in addition to ficlotasol Hasan treat dermatitis, skin infections (10g)

Dosage form Tube
Specifications Beclomethasone dipropionate, fucidin acid

Ingredient

Composition information	Content
Beclomethasone dipropionate	6.4mg
Fucidin Acid	200mg

Uses

Indications

Ficlotasol drugs are indicated in the following cases:

Dermatitis has a glucocorticoid response with bacterial infections such as eczema, atopic dermatitis, contact dermatitis, seborrheic dermatitis, psoriasis, staphylococcal dermatitis and streptococcus. Learning

Beclomethason dipropionate

Beclomethason dipropionate is a powericoid effect with strong glucocorticoid and weak mineralocorticoid effects. When used on the spot, Beclomethasone has a strong anti -inflammatory, anti -rheumatic and anti -allergy effect.

Fusidic acid

Fusidic acid is an antibiotic with steroid structure, belonging to fusidanin group, which has bactericidal and bactericidal effects, mainly acting on gram -positive bacteria. Fusidic acid inhibits protein synthetic bacteria through inhibiting an essential factor for the transfer of peptid supplementary units and the extension of the peptide chain.

Fusidic acid works well on staphylococcus strains, especially S. Aureus and S. Epidermidis (including methicillin -resistant strains). Nocardia Asteroides and many Clostridium strains are also very sensitive to the drug. Streptococcus and Enterococcus strains are less sensitive.

Most grams of Gram negative are not sensitive to fusidic acid. However, the drug works well for Neisseria spp, Bacteroides Fragilis, Mycobacterium leprae and one part on M. tuberculosis.

pharmacokinetics

Beclomethason dipropionate

Beclomethasone is easily absorbed when used on the spot. During the circulation, Beclomethasone is widely linked to plasma proteins.

Beclomethasone is metabolized mainly in the liver, excreted in the kidneys 30% of the form of unprover and 70% of metabolic forms.

Fusidic acid

Fusidic acid is well absorbed through the skin and is seen in all skin and subcutaneous structures.

Located use, the drug may absorb completely in the case of a whole body in case of wide skin damage or leg ulcers.

Eliminating drugs, mainly in the form of metabolites. The amount of excreted drugs through urine and very small hemolysis.

Before taking Drugs used in addition to ficlotasol Hasan treat dermatitis, skin infections (10g)

How to use

Apply skin.

Dosage

Apply a thin layer of medicine 1-2 times/day to the infected skin after washing. Avoid applying the drug into thick layer. Limit for 1 week of treatment.

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.

What to do when overdose?

Symptoms

The effect of increased corticosteroids does not appear early unless high doses are in a row. Body effects due to overdose may be met with sodium and water, increased appetite, mobilizing calcium and phosphorus accompanied by osteoporosis, hyperglycemia, adrenal insufficiency, increased adrenal activity.

Handling

Corticosteroid overdose, which should be monitored with serum and urine. Pay special attention to sodium and potassium balance. In case of chronic poisoning, stop the drug slowly. Treatment of electrolyte imbalance if needed.

What to do when you forget a dose? However, if close to the next dose, skip the forgotten dose and take the next dose at the time as planned. Note that it should not be used double the prescribed dose.

Side Effects

When using ficlotasol, you may experience unwanted effects (ADR).

Located local side effects, including: urticaria, erythema, itching, jaundice, skin irritation. Prolonged and high doses can cause systemic effects including:

Metabolism: common potassium, sodium hold, water retention.

Hormonal: Flashful menstrual periods, Cushing syndrome, inhibiting fetal growth and children, reducing glucose tolerance.

Muscle muscles: common muscle weakness, loss of muscle mass, osteoporosis. nerve: less common, refreshing, mood change, severe depression, insomnia. Rarely increase benign intracranial pressure.

Eyes: rarely, cataracts, glaucom.

digestive: less common, stomach ulcers, bleeding, pancreatitis, bloating, esophagus ulcer.

Instructions on how to handle ADR

When experiencing side effects of the drug, it is necessary to stop using and notify the doctor or go to the nearest medical facility for timely treatment.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

Contraindicated

Ficlotasol drugs are contraindicated in the following cases:

Sensitive to any ingredients of the drug.

Hepatic failure.

Wide skin lesions, chapped skin, sensitive, open wounds (because the drug can absorb the whole body).

Pregnant women.

Be cautious when using

Avoid applying to the mouth and eyes.

On -site antibiotics need to limit the treatment time because it can form resistant bacteria and cause superinfection of uncertainty bacteria.

Stop using the drug if the irritation, hypersensitivity or other reactions appear.

Avoid long -lasting (> 4 weeks) on a large scale (> 10% of the body surface) or leg ulcers because the drug can be absorbed into the common circulation, which leads to secondary adrenal insufficiency, creating manifestations of adrenal energy, including Cushing syndrome.

The ability to drive and operate machinery

There is no data on the effect of the drug on the ability to drive and operate machinery.

Pregnancy

should not use ficlotasol during pregnancy.

Breastfeeding period

during breastfeeding, should not use the drug in the chest area. Use only when you have carefully considered the risks and benefits.

Medicinal interaction

Fusidic acid can interact with metabolic drugs with cytochrom P450 enzymes in the liver.

With other antibacterial drugs: In vitro does not see the force of energy between fusidic acid and rifampicin or vancomycin. The antagonistic effect of ciprofloxacin has been informed.

Protease inhibit antiviral (Saquinavir, Ritonavir): There may be mutual metabolic inhibitors between protease and fusidic acid inhibitors, causing these concentrations to increase in plasma, easily causing poisoning. Avoid combining these drugs.

Storage

Where dry, less than 30 ° C.

Other drugs

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