Drugs used outside Tazoretin Gel 0.3% Medisun to treat acne (10g)

Dosage form Tube x 10g
Specifications Adapalene

Ingredient

Composition information	Content
Adapalene	0.3%

Uses

Indications

tazoretin 0.3 indicated for treatment in the following cases:

On -site treatment of regular acne in patients 12 years old and older. Adapalen is sustainable with oxygen and light and has no chemical reaction. The mechanism of action of Adapalen, like tretinoin, is to cohesion to the specific retinoic acid receptor of the nucleus, but different tretinoin is not attached to the protein of the receptor in the cytoplasm.

Adapalen when used on the skin has the effect of decomposing acne and also works on the abnormalities of the process of horny and differentiation of the epidermis, both of these cases are acne factors. The mechanism of action of adapalen is to normalize the differentiation of epithy cyst cells and thus reducing the formation of acne micro -acne.

Dynamic pharmacokinetics

In humans, adapalen is absorbed through poor skin; In clinical trials, the adapalen concentration in plasma is not found at a measured level when used long -term on a wide skin area with acne with analytical sensitivity level of 0.15 ng/mL. Therefore, it is not possible to identify the pharmacokinetic parameters about the bioavailability of adapalen when applying on the skin.

Before taking Drugs used outside Tazoretin Gel 0.3% Medisun to treat acne (10g)

How to use

tazoretin gel applied thin layer on the disease after washing and drying.

Dosage

Apply a thin layer of 0.3% tazoretin gel to the face or any skin area that needs treatment once a day in the evening, after gently washing the skin with soap with no treatment effect. Avoid applying to the skin around the eyes, lips and mucosa.

may appear a glimpse of hot or spicy sensation right after using 0.3%tazoretin gel. During the use of the drug, patients should avoid the skin to apply the drug in contact with the sun. Moisturizer can be applied to reduce dryness or irritation.

If the treatment effect is unclear after 12 weeks of treatment, it is recommended to re -evaluate the treatment therapy.

Only use on the spot. Do not use small eyes, drink or use vagina.

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.What do

do when overdose? If the drug is overdose, skin form does not improve better or faster, but also can cause erythema or uncomfortable feeling on the skin. Excessive use of Adapalene for a long time can lead to unwanted effects similar to vitamin A overdose.

Handling: If the reaction signs appear when using the drug overdose, adjust the dose or suspend the drug if necessary. Notify the treating doctor for further advice on the patient's condition.

What to do when you forget a dose? However, if close to the next dose, skip the forgotten dose and take the next dose at the time as planned. Note that it should not be used double the prescribed dose.

Side Effects

Unwanted effects (ADR) when using the 0.3% tazoretin gel that you may encounter:

Common, ADR> 1/100

Skin and soft tissue: dry skin, skin irritation, burning sensation on the skin, erythema.

Uncommon, 1/1000

Skin and soft tissue: contact dermatitis, uncomfortable skin, sunburn, itching, peeling, acne.

Not determined frequency

Skin and soft tissue: Alico dermatitis (allergic contact dermatitis), skin pain, swelling.

Eyes: irritation of the eyelids, redness of the eyelid, itchy eyelid, swelling of the eyelids.

Instructions on how to handle ADR

The drug is only used outside. Avoid contacting the drug with the eyes, mucosa, lips and mouth. If unfortunately exposed, must be washed with water.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

contraindicated

tazoretin gel 0.3% contraindicated in the following cases:

Hypersensitivity to Adapalen or any drug ingredients.

Do not take medicine for cases of severe acne.

Pregnant/nursing women, children younger than 12 years old.

Be cautious when using

If the reaction is sensitive or seriously irritated, the drug should be stopped. If the on -site irritation is controlled, patients should be instructed to use less often, stop using temporarily until the symptoms reduce or stop using completely. Do not let Tazoretin Gel 0.3% in contact with the eyes, mouth, nose angle or membrane.

If the product is exposed to the eyes, wash immediately with warm water. Do not use products for sunburnt skin or eczema with damage and scratches, should not be used in patients with severe acne on a large scale.

Should minimize exposure to sunlight and ultraviolet rays during the use of tazoretin gel 0.3%.

Products contain propylene glycol and parabens, so it can cause skin irritation and late allergic reactions.

The ability to drive and operate machinery

The drug does not affect the ability to drive and operate machinery.

Pregnancy

There is no data on drug use in pregnant women, should only be used if the benefits are superior to the risk.

breastfeeding period

Tazoretin gel 0.3% can be used during breastfeeding. To avoid contact with babies, apply 0.3% tazoretin gel to the chest during breastfeeding.

Drug interactions

have not yet recorded any interaction between the 0.3% tazoretin gel and other drugs used on the skin and the 0.3% tazoretin gel. However, it should not be used simultaneously 0.3% tazoretin gel and products containing retinoids or products with the same mechanism of action.

Adaplene basic stability with oxygen, light and no chemical reaction. In intensive studies in animals and humans, there is no toxic reaction caused by light or light allergy related to Adapalene. The safety of using Adapalene while exposed to the sun or ultraviolet irradiation has not been identified in both animals and humans.

During the use of the drug should avoid exposure to excessive sunlight or ultraviolet irradiation.

The drug is less skin -absorbing, so there is almost no interaction with other systemic drugs. There is no evidence that the effect of oral medications such as birth control pills and antibiotics is affected by the use of 0.3% tazoretin gel on the skin.

Tazoretin Gel 0.3% has a mild local irritation and thus when using the detergent, strong drying agents, astringent or irritants (aromatic and alcoholic) can cause extra stimulating effects.

However, anti -inflammatory dermatitis can be used (eg erythromycin content up to 4%) or clindamycin phosphate (1% content in base form) or 0.3% benzoyl peroxide 10% in the morning when Tazoretin Gel 0.3% is used at night because they do not reduce or increase each other's concentration.

Storage

Store in closed packaging, avoid moisture, avoid light, at temperatures below 30 ° C.

Other drugs

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