Duvita 2000mg/10ml CPC1 treatment supports in liver failure, liver dysfunction (20 tubes)
Dosage form Box of 4 blisters x 5 tubes
Specifications Arginin hydrochlorid
Ingredient Hanoi Pharmaceutical Joint Stock Company
Ingredient
| Composition information | Content |
| Arginin hydrochlorid | 2000mg |
Uses
indications
Duvita 2000mg/10ml drug indications in the following cases:
Pharmacological group: Gastrointestinal tract
arginin, like other amino dibase acids, stimulates the pituitary glands to release growth hormones and prolactin pancreatic glands release glucagon and insulin
Arginin is an essential amino acid in the urea cycle for patients who lack enzymes: N-acetylglutamate synthase (NAGS), Carbamyl Phosphate Synthetase (CPS), Ornithin Transcarbamylase (OTC), ArginininoSuccinat Synthetase (ASSS), or Arginininat (ASL).
Use Arginin hydrochloride for patients with disorder to recover arginin concentrations, helping to prevent intravenous protein catabolism for patients with ASS or ASL deficiency, which promotes ammonia consolidation into Citrullin and Argininosuccinat. These intermediate products have a less toxic urea cycle and are easier to excrete in urine than ammonia and also grant a series of biochemical reactions to eliminate nitrogen waste.
arginine increases blood glucose levels. This effect may be directly. The decomposition of glucogen and tons of glucose can also be through arginin intermediaries stimulating glucagon release.
Gastrin concentration in serum is more enhanced by arginin. The drug inhibits the recovery of the renal tubules and thus increases the excretion of protein in urine including albumin, light chain Immunoglubolin and beta, microglobulin.
Dynamic pharmacokinetics
arginin hydrochloride absorbed well through the digestive tract, the peak concentration in plasma is achieved after drinking about 2 hours. Absolute 70%bioavailability.
Arginin hydrochlorid is combined with many biochemical reaction processes. Strong metabolic drugs in the liver forming ornithin and urea by hydropping guanindin under the catalyst of Arginase.
arginin is filtered in glomerular and reabsorbed almost completely in the renal tubules.
Half lifetime eliminates 1.2 - 2 hours.
Before taking Duvita 2000mg/10ml CPC1 treatment supports in liver failure, liver dysfunction (20 tubes)
How to use
Duvita 2G is used by oral. Break the plastic tube and directly drink the solution in the tube. Can dilute with water, or drink water after taking the medication. Should be taken before the main meals or as soon as there are symptoms.
Dosage
Treatment of supporting indigestible disorders
Adults: Take 3 - 6g/day (2 - 3 tubes/day).
Supporting treatment to improve exercise ability in people with stable cardiovascular disease
Adults: Take 6 - 21g/day, each use no more than 8g (3 - 11 tubes/day).
Nutrition supplements for people with urea cycle disorders such as hyper ammonia tube I and II, hyperculifical blood citrulin, arguoSuccinicuria and N-acetyl glutamate synthetase deficiency
Adults: Take 3 - 20g/day depending on the condition (2 - 10 tubes/day).
Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.What to do when overdose? Overdose in children can lead to metabolic chlorine, brain edema or may die. Should determine the degree of shortage and calculate the amount of alkaliogens use.
In case of emergency, call the 115 emergency center immediately or go to the nearest local health station.
What to do when you forget 1 dose? However, if the time to relax with the next dose is too short, skip the dose and continue the calendar of the drug. Do not use double doses to compensate for missed dose.
Side Effects
When using the drug, there are common unwanted effects (ADR) such as:
Common, ADR> 1/100
Warnings
Before using the drug you need to read the instructions carefully and refer to the information below.
contraindicated
Duvita 2000mg/10ml drug contraindicated in the following cases:
Be cautious when using
Patients with genetic disorders in fructose tolerance, glucose-galactose absorption disorders or
Sucrose-isomaltase deficiency should not be used.
Do not use Agrinin hydrochloride with patients with atopic allergies. Antihistamine drugs are used
if the allergic reaction occurs.
Arginin hydrochlorid causes hyperkalemia to threaten life for patients with renal impairment because of the reduced discharge of potassium in these patients. Arginin should be used to be cautious for patients with kidney disease
or dawn.
For acute hypercemolic hyperactia, high doses of arginin can cause acid infections
metabolic hyperactive blood chloride, so it is necessary to monitor the concentration of chloride and bicarbonate in plasma and can simultaneously use a suitable amount of bicarbonate.
Because arginin contains high levels of nitrogen that can be metabolized, before taking the drug, it must be assessed
Master for the kidneys of high nitrogen.
Do not use Arginin for patients after myocardial infarction.
The effect of the drug on the ability to drive and operate machinery
can cause headaches, so it can affect the ability to drive and operate machinery, thus need to be cautious.
Use drugs for women during pregnancy and lactation
Pregnancy
There is no adequate and well -verified research on the use of arginin in pregnant women so they do not use this drug for women during pregnancy.
Breastfeeding period
It is not known whether arginin is secreted in a significant amount in human milk. It is necessary to consider the benefits of treatment with drugs and the risk of fetus to decide the use of drugs and stop breastfeeding.
Drug interaction
Oral contraceptives in combination with estrogen and progestogen may increase the response of growth hormones and reduce the response of glucagon and insulin and arginin.
Insulin concentration in plasma after arginin stimulation can be increased by thiazid, xylitol and aminophylin diuretics. The following two drugs also reduce the response of glucagon in plasma with arginine. The following two drugs also reduce the response of glucagon with arginine. For a long time, Sulfonyl URE, oral diabetes, can prevent glucagon response in plasma with arginin. Phenytoin reduces insulin response in plasma with arginin, when patients do not tolerate glucose intolerant to glucose.
Hypered hyperkalemia occurs after arginin therapy for metabolic alkaline infection in several patients with severe liver disease that has just been used Spironolacton. Patients who use diuretics reduce potassium consumption are at high risk of hyperkalemia caused by arginine, and thus avoid combining these drugs.Storage
Leave a cool place, avoid light, temperature below 30⁰C.
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