Eastern Tphgold powder treatment for conscious disorders (20 packs x 4g)

Dosage form Box of 20 packs x 4g
Specifications L-Ornithine-L-ASPARTATE

Ingredient

Composition information	Content
L-Ornithine-L-ASPARTATE	3G

Uses

indications

TPHOLD 3G drugs are indicated in the following cases:

Ammonia increases related to acute and chronic liver disease, cirrhosis, fatty liver, hepatitis. Detoxification by reducing ammonia levels in the liver and brain.

A few clinical trials with effective reporting of blood ammonia reduces blood ammonia by increasing URE synthesis. However, there are still many unanimous views on the hypotension effect of L - Ornithine L - Aspartate.

L - Ornithine L - Aspartate stimulates the process of detoxifying ammonia by increasing URE synthesis in the URE cycle, in addition it also eliminates the liver ammonia from the liver from tissues, so it has the effect of detoxifying and protecting the liver cells.

In addition, L - Ornithine L - Aspartate also produces energy in the form of ATP, thereby improving the energy balance of the liver.

Mechanism of action:

L - Ornithine L - Aspartate is the durable salt of 2 amino acids ornithine and aspartic acid. Both Ornithine and Aspartate are of endogenous origin, involved in many metabolic processes in the body. L - Ornithine L - Aspartate stimulates the synthesis of URE and Glutamine rings, playing an important role in the mechanism of ammonia detoxification in the liver and brain.

Aspartate and ornithine stimulate the formation of α - ketoglutarate and glutamate to reduce the concentration of ammonia in the brain.

Aspartate and ornithine stimulate the formation of ATP related to the T.C.A cycle and stimulate the energy transfer between the mitochondrial space and the mitochondria, which is related to the Malate - Aspartate path.

Aspartate plays a very important role in the biosynthesis of Purine and Pyrimidine.

pharmacokinetics

l - Ornithine L - Aspartate offers 2 important substrates for both URE and Glutamine synthesis. After drinking, L - Ornithine L - Aspartate is separated into L - Ornithine and L - Aspartic Acid, 2 substances that are then absorbed in the small intestine by active transportation via the brush brush of the small intestine epithelium, that absorption depends on the Na+ionic concentration gradient. Oral bioavailability of L - Ornithine L - Aspartate is 82.2 ± 28%. Ornithine can go through the bloody barrier.

Before taking Eastern Tphgold powder treatment for conscious disorders (20 packs x 4g)

How to use

tphgold oral.

Dissolve the drug in an appropriate amount of water (a glass of pure water, tea or fruit), drink after eating.

Dosage

Starting dose 1000 mg x 3 times/day, taking after meals.

Maintenance dose 1000 mg 3 times/day for at least 4-6 weeks.

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.

What to do when overdose?

No report on overdose.

In an emergency, call the 115 emergency center immediately or go to the nearest local health station.

What to do when you forget a dose? However, if close to the next dose, skip the forgotten dose and take the next dose at the time as planned. Do not drink twice as prescribed.

Side Effects

When using TPHOLD 3G drug, you may experience unwanted effects (ADR).

Unwanted effects such as nausea and vomiting rarely occur. These unwanted effects usually only occur in a short time and do not need to stop taking the drug.

The burning sensation in the larynx or nausea may occur, but rare.

Notify the doctor with unwanted effects when using the drug.

Instructions on how to handle ADR

Stop using the drug. With minor adverse reactions, usually just stop the drug. In case of severe sensitivity or allergic reactions, supportive treatment (airy keeping and using epinephrine, oxygen breathing, antihistamine, corticosteroids ...).

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

Contraindicated

TPHOLD 3G drug is contraindicated in the following cases:

Patients with hypersensitivity to any ingredients of the drug.

Creatinin serum below 3mg/100 ml.

Be cautious when using

Use cautiously in pregnant and lactating women.

Use carefully in the elderly, people with impaired renal function.

High doses need to control urea levels in plasma and urine.

There is no evidence of safety and efficiency in pregnant women. However, can be used for pregnant women and the elderly.

To be out of reach of children.

The ability to drive and operate machinery

should be cautious when used for driving objects and operating machinery.

Pregnancy

should avoid being used for pregnant and lactating women. However, it is necessary to treat, so carefully evaluate the benefits and risks.

Breastfeeding period

should be avoided for pregnant and lactating women. However, it is necessary to treat, so carefully evaluate the benefits and risks.

Drug interaction

There is no information on drug interaction with TPHOLD 3G.

Storage

In a dry place, avoid light, temperature below 30 ° C.

August 12, 2018, establishing Phuong Dong Pharmaceutical and Trading Co., Ltd, formerly a distributor of health and pharmaceutical foods. Business of the main industries: Producing processing health food products. In October 2010, the company switched to the production of health food products: Tea nuggets, syrups and hard capsules, tablets and film tablets, soft capsules. Currently, the company has completed the factory with an area of over 7000 m2, with 4 factories invested in synchronously and modernly, meeting the standard of advanced quality management systems (ISO 9001, ISO 22000, GMP - WHO ...).

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