Ebastine Normon 10mg treatment of allergic rhinitis, idiopathic urticaria (2 blisters x 10 tablets)

Dosage form Box of 2 blisters x 10 tablets
Specifications Ebastine

Ingredient

Composition information	Content
Ebastine	10mg

Uses

Indications

Ebastine Normon 10mg is indicated in the following cases:

Treatment of allergic symptoms such as allergic rhinitis, seasonal conjunctivitis or year -round (runny nose, itchy nose, itchy eye, crying, sneezing ...).

Allergic dermatitis.

pharmacokinetic

absorption

Ebastin is quickly absorbed and undergoing the transformation right after drinking.

Distribution, metabolism and elimination

Ebastin is almost completely converted into active acid metabolites as CAREBASTIN through CYP3A4. After taking a single dose of 10 mg of Carebastin's peak plasma concentration achieved at 2-6 hours and reaching 80 - 100 ng/ml.

Both Ebastin and Carebastin have a high ratio of plasma proteins (over 95%).

Carebastin's waste time is from 15 to 19 hours with 66% of the drug excreted in the urine in the form of a combination. After taking 10 mg dose repeated once a day, the noise status is achieved for 3-5 days with peak concentration in plasma from 130 - 160 ng/ml.

In patients with severe renal impairment, Carebastin's waste time increases to 23 - 27 hours. So be cautious when increasing the dose for these patients.

Before taking Ebastine Normon 10mg treatment of allergic rhinitis, idiopathic urticaria (2 blisters x 10 tablets)

How to use

Take oral use, should drink in the morning.

Dosage

Adults and children over 12 years: 1 tablet 10mg/time/day.

In case of severe symptoms can be used a 2 -doses a day 10mg divided 2 times.

Patients with hepatic failure: daily dose must not exceed 10mg/day.

Not for patients under 12 years old.

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.

What to do when overdose?

However, the use of increasing dose is only determined by experienced specialists.

If there is any sign of overdose of drug poisoning, gastric lavage and appropriate symptomatic treatment.

Overdose medication can cause gastrointestinal symptoms such as abdominal pain, nausea, vomiting, headache.

Management:

Stop taking the drug, immediately notify the doctor/pharmacist, or go to the nearest medical facility for gastric lavage and symptomatic treatment.

What to do when you forget a dose? However, if close to the next dose, skip the forgotten dose and take the next dose at the time as planned. Note that it should not be used double the prescribed dose.

Side Effects

When using Ebastine Normon, you may experience unwanted effects (ADR).

Common, ADR> 1/100

Systemic: headache, dry mouth, drowsiness.

Uncommon, ADR

Respiratory: Nosebleeds, rhinitis, sinusitis.

digestive: abdominal pain, indigestion, nausea.

Mental: Difficult to sleep.

Instructions on how to handle ADR

When experiencing side effects of the drug, it is necessary to stop using and notify the doctor or go to the nearest medical facility for timely treatment.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

Contraindicated

Ebastine Normon is contraindicated in the following cases:

Patients with hypersensitivity to any ingredients of the drug.

Patients with severe liver failure.

Precautions when using

Patients under 12 years old.

Patients with abnormal electrocardiogram test results, prolonged QT interval.

Patients are using ketoconazole and macrolide antibiotics.

The ability to drive and operate machinery

Do not use drugs for people while driving or operating machinery due to drugs that can cause symptoms such as drowsiness, headache.

Pregnancy

should not be used during pregnancy, in case of necessity, a doctor/pharmacist should be consulted before use.

Breastfeeding period

Ebastin has not been confirmed whether it is excreted in breast milk or not, so it should not be used during breastfeeding.

Drug interaction

simultaneous use of Ebastin with antihistamine resistance increases the antihistamine effect.

When used with ketoconazole or macrolide antibiotics, increase QT.

Ebastin affects the diagnosis of skin allergies, so it is not advisable to test after 5-7 days of stopping the drug.

Storage

less than 300C, in a dry place, avoid light.

Other drugs

Disclaimer

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