Eighteen gel Phil on the spot acne (10g)
Dosage form Tube
Specifications Erythomycin
Ingredient
Thành phần cho 10g
| Composition information | Content |
| Erythomycin | 400mg |
Uses
indications
Eighteen 10g drug is indicated in the following case:
Local acne treatment (inflamed acne accompanied by pustules and lumpy).
Pharmacokology
erythromycin is an antibiotic of a macrolide group with in vito and in vivo on most Gram -positive aerobic and anaerobic bacteria as well as on some gram -negative bacilli.
erythromycin is usually bactericidal but can also be bactericidal at high concentrations or on highly sensitive bacteria.
erythromycin inhibits the synthesis of protein synthesis of sensitive bacteria by cohesion to recover into the ribosom 50s unit. When applied to the skin, the drug inhibits the growth of sensitive bacteria (mainly propionibacterium acnes) on the skin and reduces the concentration of free fatty acids in sebum. The reduction of free fatty acids in sebum may be an indirect consequence of the inhibition of lipase -secreting bacteria triglycerides into free fatty acids; Or maybe a direct result of the intervention of the lipase secretion in these bacteria.
Free fatty acids are acne -causing substances and are considered to be the cause of inflammation (such as papules, pustules, acne, acne) of acne. However, other mechanisms such as direct anti -inflammatory effects of erythromycin may participate in the clinical improvement of acne observed when treated on the spot with erythromycin.
Dynamic pharmacokinetics
This drug shows that there is no body absorption when applied on the skin intact and unknown whether Erythromycin is absorbed through scratched skin, wounds or mucosa.
Before taking Eighteen gel Phil on the spot acne (10g)
How to use
Apply to the skin.
Dosage
Apply medicine 1-2 times daily, after washing acne -prone skin with warm and dry water.
Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.What do
do when overdose? If you use too many drugs, you will not achieve faster or better results but may be red, peeling or discomfort. Oral toxicity on mice is higher than 10 ml/kg.
When drinking wrong, unless swallowing only a small amount, it is advisable to consider the appropriate stomach method.
What to do when you forget a dose? However, if close to the next dose, skip the forgotten dose and take the next dose at the time as planned. Note that it should not be used double the prescribed dose.
Side Effects
When using Eighteen 10g, you may experience unwanted effects (ADR).
Rare, 1/10000 Skin: Hypersensitivity, may be rash. Not determined frequency Skin: dry skin, itching, erythema, burning sensation. Instructions on how to handle ADR If you have a rash, you must stop taking the drug immediately. Notify the doctor the unwanted effects when using the drug.
Warnings
Before using the drug you need to read the instructions carefully and refer to the information below.
Contraindicated
Eighteen 10g drug is contraindicated in the following case:
Patients with hypersensitivity to this drug or macrolid antibiotics.
Be cautious when used
To avoid the case of resistance bacteria, it is necessary to determine the sensitivity of bacteria and use the drug in the minimum time.
Must monitor closely because hypersensitivity reactions may occur. If the symptoms of hypersensitivity (itching, skin redness, swelling, lumpy, herpes ...) appear, must stop taking the drug.
This drug is only used on the skin, avoiding the drug to stick to the eyes or mucosa (including eye and mouth mucosa).
Avoid sticking to sticking to clothes or other items.
If taking the drug for a long time, it can cause anti -drug bacteria.
In this case, medication must be stopped and applied appropriate therapies.
Because the drug contains propylene glycol, it is necessary to take care of patients with hypersensitivity to this substance or patients with a history of allergies.
The ability to drive and operate machinery
does not affect.
Pregnancy
The safety of drugs for pregnant women has not been determined. Therefore, only pregnant women should be used when they are really necessary.
The period of breastfeeding
The safety of the drug for breastfeeding women has not been determined. Therefore, only medication for breastfeeding women should be really necessary.
Interactive drug
Take medication simultaneously with on -site preparations for acne and peeling or peeling drugs that can occur blistering. Therefore, be careful.
Do not use this combination of drugs with clindamycin and lincycin.
Storage
In closed box, avoid light, at temperatures below 30 ° C.
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