Elacox 400 medicine treats symptoms of osteoarthritis, acute or chronic rheumatoid arthritis (1 blister x 10 tablets)

Dosage form Box of 1 blister x 10 tablets
Specifications Etodolac

Ingredient

Composition information	Content
Etodolac	400mg

Uses

Indications

Elacox 400 are indicated in the following cases:

Treat the symptoms of osteoarthritis and rheumatoid or chronic arthritis. Reduce fever.

pharmacokinetics

Etodolac is well absorbed, the peak concentration of plasma is reached in about 80 ± 30 minutes. Etodolac's absorption level is not affected when used after meals, but when used simultaneously with the maximum concentration of food, it is reduced by about 1.5 times and the time to achieve this concentration increases from 1.4 to 3.8 hours.

Etodolac's average distribution volume is approximately 390 ml/kg, 99% combined with plasma proteins, mainly albumin.

Etodolac is metabolized mainly in the liver. Elimination mainly through the kidneys. Etodolac's waste sale time (T1/2) is 6.4 hours. Elimination through stool is about 16% of the dose.

Before taking Elacox 400 medicine treats symptoms of osteoarthritis, acute or chronic rheumatoid arthritis (1 blister x 10 tablets)

How to use

Elacox 400 used in or immediately after eating.

Dosage

Acute pain treatment: 200 - 400mg every 6-8 hours. Up to 1000mg/day. In some patients used up to 1200mg/day.

Treatment of chronic pain: starting 800-1200mg divided 2-4 times/day, maintaining 600-1200mg divided 2-4 times/day.

Treatment of osteoarthritis and rheumatoid arthritis: Take 400mg 2 times/day. If necessary, the dose can be increased to 1200mg/day.

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.What to do when using overdose?

What to do when you forget a dose? However, if close to the next dose, skip the forgotten dose and take the next dose at the time as planned. Note that it should not be used double the prescribed dose.

Side Effects

The unwanted effects are usually light and transient including:

chills, fever. Edema, anemia.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

Contraindicated

Elacox 400 contraindicated in the following cases:

Hypersensitivity to Etodolac or one of the ingredients of the drug. establishment.

Be cautious when using

Use carefully for patients with a history of stomach ulcer, duodenum, gastrointestinal bleeding.

Caution for patients with cardiovascular disease, hypertension and the elderly.

Need to carefully monitor kidney function and urine excretion in patients with heart failure, liver failure, chronic kidney failure or patients taking diuretics.

Periodically check hemoglobin and hematocrit to detect anemia that can sometimes occur in patients using nonsteroidal anti -inflammatory drugs.

Patients using Elacox 400 may give a false positive reaction to bilirubin, urine due to the presence of Etodolac phenolic metabolites in urine.

affects the ability to drive and operate machinery

Use carefully for the driver and operate machinery because Elacox 400 can cause dizziness, blurred vision for users.

Pregnant and lactating women

Pregnant women:

The drug can be harmful to the fetus. Do not use Etodolac for the last 3 months of pregnancy.

Do not use Etodolac during pregnancy unless the doctor is indicated.

breastfeeding women:

There is no information on whether Etodolac is secreted into breast milk or not, as well as can harm the breastfeeding or not. Therefore, do not use drugs in breastfeeding women.

Drug interaction

Etodolac's concentrations can reduce the concentration of Etodolac.

Use at the same time as aspirin and other nonsteroidal anti -inflammatory drugs that increase the effects of the drug.

When used with warfarin, it reduces the binding to the protein of this substance.

Etodolac when used with cycloserin, digoxin, lithium, methotrexate will reduce the clearance of these substances and increase toxicity.

Storage

Leave a cool place, avoid light, temperature below 30⁰C.

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