Ellosin Capsule Arlico is diluted in acute and chronic respiratory disease (3 blisters x 10 tablets)

Dosage form Box of 3 blisters x 10 tablets
Specifications Erdosteine

Ingredient

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Composition information	Content
Erdosteine	300mg

Uses

Indications

Erdosin drugs are indicated to dilute phlegm in cases of acute and chronic respiratory diseases in adults.

Pharmacokinus

erdosteine has the effect of stabilizing the secretion of mucus, which works to dilute phlegm, easily coughing up.

Erdosteine has the effect of protecting bronchial, protecting the enzyme α1-antitrysin, increasing the amount of IgA antibodies in the blood. Therefore, Erdosteine has the effect of protecting bronchial, increasing the ability to fight bacteria.

The advantage of Erdosteine compared to other thiol groups is that the less irritating drugs because the Thiol (SH) group in the molecule has been locked by other groups.

pharmacokinetic

absorption

Erdosteine is quickly absorbed after oral and quickly metabolizes the liver into the liver into a biological metabolic substance, n-tiodiglycolyl-homocystein (M1).

After taking the dose of 300 mg, the maximum concentration (CMAX) of Erdosteine in plasma reaches 1.26 ± 0.23 µ/ml after taking 1.18 ± 0.26 hours (TMAX), while CMAX of M1 is 3.46 µ/ml for TMAX is 1.48 hours.

The plasma concentration of Erdosteine increases the dose depends on the dose. The plasma concentration of M1 also increases with the dose, but is not proportional to the non -metabolic ErDosteine.

The absorption of drugs does not depend on food.

Distribution

In animal studies, Erdosteine is distributed mainly to the kidneys, bones, spinal cord and liver. The pharmacological activity of Erdosteine and M1 has been found while washing bronchial - alveoli.

Elimination

Erdosteine and m1 waste time is 1.46 ± 0.60h and 1.62 ± 0.59H. In urine, only M1 and sulphats are found, excreted through insignificant stool.

There is no accumulation or metabolism of Erdosteine and M1 observed after taking daily dose 600 - 900 mg in 8 days.

influenced by age factors.

Age does not change the pharmacokinetics of Erdosteine.

Links to plasma proteins.

The amount of Erdosteine binding to plasma proteins is 64.5% (about 50 - 86%).

Before taking Ellosin Capsule Arlico is diluted in acute and chronic respiratory disease (3 blisters x 10 tablets)

How to use

Oral drugs, swallow pills with a cup of water.

Dosage

Elderly and adults over 18 years old: take 1 capsule/time, 2 times/day for up to 10 days.

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.

What to do when overdose? The overdose should not be used, in case of overdose, patients need to be taken care of symptoms.

In an emergency, call the 115 emergency center immediately or go to the nearest local health station.

What to do when forgetting a dose? However, if the time to relax with the next dose is too short, skip the dose and continue the calendar of the drug. Do not use double dose to compensate for missed dose.

Side Effects

When using illsin, you may experience unwanted effects (ADR).

Unwanted effects are rare (less than 0.01% of the total number of users). Stomach pain, shortness of breath, cough, diarrhea, eczema, headache, vomiting, skin erythematosus, change taste, vomiting.

When experiencing side effects of the drug, it is necessary to stop using and notify the doctor or go to the nearest medical facility for timely treatment.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

Contraindicated

Ellosin drugs contraindicated in the following cases:

Hypersensitivity to any ingredients of the drug.

Do not have data in patients with creatinine clearance Patients with progressive stomach ulcer.

Pregnant and lactating women have no data on drug use on these objects.

Precautions when using

The following cases should be very careful when using:

Patients with stomach ulcers.

Patients with kidney and liver disease.

Be cautious when used for patients under 18 years old.

The ability to drive and operate machinery

because the drug has side effects that cause headaches, dizziness, and caution when used for jobs that require alertness such as driving and operating machinery.

Pregnancy and nursing mothers

Due to not having enough safe data when used for pregnant and lactating women, so contraindicated when used for these two subjects.

Drug interaction

There are no reports on Erdosteine's interaction with drugs.

It is possible to coordinate Erdosteine with antibiotics and bronchodilators such as theophylline, receptor stimulants β2-adrenergic, cough reduction drugs.

Storage

Leave a cool place, avoid light, temperature below 30⁰C.

To be out of reach of children.

Other drugs

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