Emanera 40mg Krka Treatment Treatment of Gastroesophageal reflux (4 blisters x 7 tablets)

Dosage form Box of 4 blisters x 7 tablets
Specifications Esomeprazol

Ingredient

Composition information	Content
Esomeprazol	40mg

Uses

indications

Emanera 40mg drug indicated in the following cases:

adolescents over 12 years old

Gastroesophageal reflux disease (GERD):

Treatment of esophageal ulcerative ulcer.

Adults

Gastroesophageal reflux disease (GERD):

Treatment of esophageal ulcerative ulcer.

Heals gastric and duodenal sores caused by Helicobacter pylori.

Prevention of ulcers in patients who are using NSAIDs or patients at risk. whether.

pharmacokinetics

No data ,.

Before taking Emanera 40mg Krka Treatment Treatment of Gastroesophageal reflux (4 blisters x 7 tablets)

How to use

EMANERA 40mg drug used oral. Take medicine at any time of the day.

Can be taken before or after eating.

Swallow the tablet with water, do not chew or crush before drinking.

Dosage

Adults and children over 12 years old

Gastroesophageal reflux disease:

Treatment of esophageal ulcer due to reflux: 40mg per day for 4 weeks. Can be used for 4 more weeks with patients who still have inflammation. Amoxicillin and 500mg Clarithromycin, 2 times a day within 7 days.

Treatment of stomach ulcers due to the use of anti-inflammatory drugs NSAID: 20mg per day for 4-8 weeks. Esomeprazol 40mg, twice a day. Then adjust according to the response of each patient and continue treatment when clinical indications.

People with kidney function damage: No need to adjust the dose in patients with renal function damage. Due to less experience in using drugs in patients.

People who damage liver function: No need to reduce the dose in people with liver function damage to a mild to medium level. In patients with severe liver failure, maximum overdose of 20mg Esomeprazol.

Elderly: No need to adjust the dose in the elderly.

Children under 12 years of age: There is no research data when using Esomeprazol for children under 12 years old.

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.What to do when using overdose?

What to do when you forget 1 dose? However, if the time to relax with the next dose is too short, skip the dose and continue the calendar of the drug. Do not use double dose to compensate for missed dose.

Side Effects

Unwanted effects (ADR) when using Emanera 40mg that you may encounter:

Common

Nervous system disorders: headache.

Metabolic and nutritious disorders: peripheral edema.

Mental disorders: Insomnia

Musculoskeletal and connective tissue disorders: hip, wrist and spine fractures.

Rare:

Blood disorders and lymphatic systems: leukopenia, thrombocytopenia. Enlightenment.

eye disorders: blurred vision. Gloomy with light. In some patients with the accompanying kidney failure.

Blood disorders and lymphatic systems: leukemia, all bloody hematoma. Hypergenia can also lead to hypotension. Mechanical.

Gastrointestinal disorders: Micro colitis.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

contraindicated

EMANERA 40mg drug contraindicated in the following cases:

Hypersensitivity to Esomeprazole, Benzimidazoles group or any ingredient of the drug.

Be cautious when using

when there is any alarm symptom (such as significant weight loss, recurrent vomiting, difficulty swallowing, vomiting blood or black stools) and suspicion or stomach ulcers should eliminate malignant diseases because Esomeprazol treatment can reduce symptoms and delay diagnostic.

Patients with long -term treatment (especially in people who treat more than 1 year) should be monitored regularly.

Patients treated according to the regime when necessary should contact the doctor if there are symptoms that change in characteristics. When prescribing Esomeprazol according to the treatment regime when necessary, it is advisable to consider the interaction associated with other drugs due to the change in the plasma Esomeprazol level.

Patients with rare genetic problems such as fructose intolerance, malventia-galucose-galactose loss of sucrase-isomaltase lack of esomeprazol should not be used.

Proton pump inhibitors may increase the risk of gastrointestinal infections compared to Salmonella and Campylobacter.

It is not recommended to simultaneously use Esomeprazol with Atazanavir. If the combination of Atazanavir with proton pump inhibitors is inevitable, closely monitoring.

Esomeprazol can reduce vitamin B12 absorption. Therefore, it is necessary to consider when using drugs in people with reduced vitamin B12 reserves or risk factors for reducing vitamin B12 absorption when long -term treatment.

Do not encourage simultaneous use of esomeprazol and clopidogrel.

Patients with osteoporosis should be taken care of under the current clinical instructions and should be added with an appropriate amount of vitamin D and calcium.

Drug interaction

Esomeprazol's impact on pharmacokinetics of other drugs:

For pH -dependent absorption drugs: It is not recommended to use Esomeprazol simultaneously with Atazanavir and contraindicated using Esomeprazol simultaneously with Nelfinavir.

Metabolic drugs simultaneously with nelfinavir.

CYP2C19 metabolic drugs:

should monitor patients when starting and when terminated at the same time, Esomeprazol with Warfarin or other Coumarin derivatives because the drug can cause a significant increase in Inr clinical. Clinically related to simultaneous use of Esomeprazol with Naproxen. So when using high doses of methotrexate, it is advisable to temporarily pause Esomeprazol.

Effect of other drugs on Esomeprazole's pharmacokinetics:

Esomeprazol is metabolized by CYP2C19 and CYP3A4. CYP2C19 and CYP3A4 can reduce serum Esomeprazole concentration due to Esomeprazole metabolism.

Storage

Leave a cool place, avoid light, temperature below 30⁰C.

Other drugs

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