Emycin DHG 250 powder treat infection (24 packs x 1.5g)

Dosage form Box of 24 packs x 1.5g
Specifications Erythromycin

Ingredient

Composition information	Content
Erythromycin	250mg

Uses

Indications

Emycin DHG 250 medicine is indicated in the following cases:

Treatment of diseases: respiratory infections, gastrointestinal tract, skin and soft tissue infection, newborn conjunctivitis and chlamydia conjunctivitis.

Preventive recurrence of rheumatism. The main effect of erythromycin is bactericidal but can kill bacteria at high concentrations for very sensitive strains. Erythromycin and other macrolids associate with the 50S subunit of ribosom sensitive bacteria and inhibit protein synthesis. The effect of the drug increases in mild alkaline pH (about 8.5), especially with Gram -negative bacteria. Erythromycin has a wide antibacterial spectrum including Gram -positive bacteria, Streptococcus Pneumoniae, Streptococcus Pyogenes, Staphylococcus aureus, Bacillus anthracis, Corynebacterium diphteria, olysipelothris rhusioparthiae, Listeria monocyogenes.

Medium -acting drugs with anaerobic bacteria like Clostridium spp., Propionibacterium acnes. Erythromycin works with Gram -negative bacteria such as Neisseria Meningitidis, N. Gonorrheae and Moraxella (Branhamella) CatVrhalis, Bordetella spp and Pasteurella, Haemophilus Ducreyi, Helicobacter PyloRidis, Campylobacter Jejuni. Other bacteria sensitive to drugs include Actinomyces, Chlamydia, Rickettsia spp.

pharmacokinetics

erythromycin is widely distributed throughout fluids and tissues, including middle leaking fluid, prostate fluid, semen. The highest concentration is seen in the liver, bile and spleen. Erythromycin has low concentrations in cerebrospinal fluid, but when the meninges are inflamed, the concentration of erythromycin in the cerebrospinal fluid increases. From 70% to 90% of erythromycin attached to protein. More than 90% of Erythromycin metabolizes in the liver, partly in the form of inactiveness; The accumulation of severe liver failure is accumulated. Erythromycin excreted mainly into the bile. From 2% to 5% of oral doses excreted in urine in the form of unchanged.

Before taking Emycin DHG 250 powder treat infection (24 packs x 1.5g)

How to use

Take it right before the meal, must take the drug according to the procedure (5 - 10 days).

Dosage

Children

Normal dose 30 - 50mg/kg body weight/day, divided 2-4 times orally.

Children under 2 years old

Take 1/2 pack x 4 times/day (total dose 500mg/day).

Children from 2 to 8 years old

Take 1 pack of 4 times/day (total dose of 1g/day).

In case of severe doses of infections can doubled.

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.

What to do when overdose?

What to do when you forget a dose? However, if close to the next dose, skip the forgotten dose and take the next dose at the time as planned. Note that it should not be used double the prescribed dose.

Side Effects

When using Emycin DHG 250, you may experience unwanted effects (ADR).

Common, ADR> 1/100

Abdominal pain, vomiting, diarrhea, rash.

Uncommon, 1/1000

urticaria.

Rare, ADR

Answer reaction, arrhythmia, increased transaminase, serum bilirubin increased, cholestasis in the liver, deafness recovered.

Instructions on how to handle ADR

When experiencing side effects of the drug, it is necessary to stop using and notify the doctor or go to the nearest medical facility for timely treatment.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

Contraindicated

EMYCIN DHG 250 contraindications in the following cases:

Patients with hypersensitivity to erythromycin.

Patients who used to use erythromycin that had liver disorders.

Patients with a history of deafness.

The use is considered unsafe for patients with acute porphyrin metabolism disorders, because of acute batches.

Do not coordinate with terfenadin, especially in the case of patients with heart disease, arrhythmia, bradycardia, long Q -t -t - ischemic heart, or patients with electrolytes.

Be cautious when using

Need to use very carefully erythromycin for patients who are liver or liver failure. Be cautious when used with patients with arrhythmia and other heart disease.

The ability to drive and operate machinery

There is no impact on the ability to drive and operate machinery.

Pregnancy

erythromycin passes through the placenta. Estythromycin estolate is not used for pregnant people because of the increased risk of liver toxicity. Problems for other forms of erythromycin without notice.

Breastfeeding period

erythromycin secreted into breast milk, but there is no notice of unwanted effects for breastfed children with erythromycin.

Drug interaction

No combination of Astemizol or Terfenadin with erythromycin because of the risk of toxicity with heart such as torsion, ventricular tachycardia and death.

erythromycin can inhibit metabolism of carbamazepin and valproic acid, increasing the concentration of these drugs in plasma and increasing toxicity. Erythromycin may be antagonistic with chloramphenicol or lincycin.

erythromycin reduces the clearance of the following drugs: xanthins such as aminophylin, theophylin, caffeine, alfentanil, Midazolam or triazolam. Therefore increasing the concentration and duration of these drugs.

erythromycin can extend over the prothrombin time and increase the risk of bleeding during long -term treatment with warfarin, due to reduced metabolism and clearance of this drug. Erythromycin increases plasma ciclosporin levels and increases the risk of toxicity to the kidneys.

erythromycin inhibits the metabolism of ergotamine and increases the vascular spasms of this drug. Be cautious when using erythromycin along with lovastatin and can increase the risk of muscle pattern.

Storage

In a dry place, the temperature does not exceed 300C, avoiding light.

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