Erythromycin 500mg Mekophar Treatment of infection (10 blisters x 10 tablets)

Dosage form Box of 10 blisters x 10 tablets
Specifications Erythromycin

Ingredient

Composition informationContent
Erythromycin500mg

Uses

indications

erythromycin is indicated in the following cases:

  • Respiratory, skin and soft tissue infections, urinary-genital organs, gastrointestinal tract.

    Pharmacology

    erythromycin is a macrolide antibiotic, with a broad spectrum. Bacterial strains are also sensitive to erythromycin:

  • Gram -positive bacteria: Bacillus anthracis, corynebacterium diphteria, erysipelothris rhusioparthiae, listeria monocyogenes ... Pasteurella, Haemophilus ducreyi, Helicobacter PyloRidis, Campylobacter Jejuni.
  • Other bacteria: Actinomyces, Chlamydia, Rickettsia spp Mycoplasma Kansasii. Movies (base and stearate) are easy to lose activity by gastric, it is best to drink at hunger.

    erythromycin is excreted mainly into the bile, from 2-5% of oral doses to emit urine in the form of unchanged.

  • Before taking Erythromycin 500mg Mekophar Treatment of infection (10 blisters x 10 tablets)

    How to use

    Should take medicine at hunger, if digestive irritation, take it while eating.

    Dosage

    Dosage:

    Adults

    Take 500 - 1000 mg/time, 2-3 times a day.

    Children

    Take 30– 50 mg/kg/day, divide 2-3 times.

    Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.What to do when overdose?

    Symptoms

    Overdose of erythromycin often has symptoms of abdominal pain, vomiting, diarrhea, hearing loss (temporary).

    How to handle

    For epinephrin, corticosteroids and antihistamine drugs to handle allergic reactions; Stomach douche to eliminate unprocessed drugs from the body; And when you need to use supportive measures.

    If the overdose occurs, it is recommended to go to the nearest medical facility for medical staff to have treatment methods.

    What to do when forgetting 1 dose?

    Not recorded.

    Side Effects

    When using erythromycin, you may experience unwanted effects (ADR).

    Common, ADR> 1/100

  • Abdominal pain, vomiting, diarrhea, foreign rash ...
  • Uncommon, 1/1000

  • Skin: urticaria.
  • Rare

  • Arrhythmic, hyperpentine transaminase, hyperlirubin blood, deafness recovered.
  • Instructions on how to handle ADR

    When experiencing side effects of the drug, it is necessary to stop using and notify the doctor or go to the nearest medical facility for timely treatment.

    Warnings

    Before using the drug you need to read the instructions carefully and refer to the information below.

    contraindicated

    Erythromycin drug contraindicated in the following cases:

  • Sensitive to any ingredients of the drug.
  • Patients who had previously used erythromycin that had liver disorders, patients with a history of deafness, patients with acute porphyrin metabolism disorders.
  • Collaborate with Terfenadine, Astemizole.
  • Be cautious when using

    Need to use very carefully in the form of erythromycin for patients who are liver or liver failure.

    It is necessary to be very cautious when used for patients with arrhythmia, with other heart diseases. In this case, drug interactions can cause deadly side effects.

    The ability to drive and operate machinery

    has not seen the drug that affects the ability to drive and operate the machine.

    Pregnancy

    Precautions when used for pregnant women.

    breastfeeding period

    Be cautious when used for breastfeeding women.

    Drug interaction

    contraindicated use of astemizole or terfenadine with erythromycin because of the risk of toxicity with heart such as torsion, ventricular tachycardia and death.

    Be careful when using erythromycin along with the following drugs:

    erythromycin reduces plasma clearance and prolongs the duration of the effect of alfentanil.

    erythromycin can inhibit metabolism of carbamazepine and valproic acid, increasing the concentration of these drugs in plasma and increasing toxicity.

    erythromycin can push or prevent chloramphenicol or lincomycin from bacterial ribosom subuniters, so antagonistic effects of these drugs.

    Purple -bactericidal medications can affect penicillin's bactericidal effects in the treatment of meningitis or cases that need to have a rapid bactericidal effect. It is best to avoid coordination.

    erythromycin increases the concentration of Digoxin in the blood due to the impact on the intestinal bacteria, which makes the digoxin not inactive.

    erythromycin reduces the clearance of xanthin such as aminophylline, theophyllline, caffeine, thus increasing the concentration of these substances in the blood. If necessary, dose adjustment.

    erythromycin can extend over the prothrombin time and increase the risk of bleeding during long -term treatment with warfarin, due to reduced metabolism and clearance of this drug. Warfarin dose should be adjusted and closely monitor prothrombin time.

    erythromycin reduces the clearance of Midazolam or Triazolam and increases the effects of these drugs.

    High doses of erythromycin with toxic drugs with ear impaired patients can increase the potential of toxicity to the ears of these drugs.

    Combining erythromycin with toxic drugs with the liver can increase the toxicity of the liver.

    erythromycin increases cyclosporin levels in plasma and increases the risk of toxicity to the kidneys.

    erythromycin inhibits the metabolism of ergotamine and increases the vascular spasms of this drug.

    Using erythromycin along with lovastatin may increase the risk of muscle pattern.

    Storage

    Store in dry places, the temperature does not exceed 30 ° C, avoiding light.

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