Espumisan drugs treat symptoms of flatulence and bloating (2 blisters x 25 tablets)

Dosage form Soft capsules
Specifications Box of 2 blisters x 25 tablets
Ingredient Simethicone
Indication Flatulence, bloating

Ingredient

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Composition information	Content
Simethicone	40mg

Uses

indications

Espumisan 40mg drugs are indicated in the following cases:

Treatment of symptoms related to gas accumulation in the gastrointestinal tract such as flatulence, bloating. abdominal). Simeticone reduces the surface tension of air bubbles, broke or gathered them and was expelled, thereby anti -flatulence.

Simethicone has no toxicity, is a chemical inert and well tolerated so it is convenient for treatment, preventing unpleasant sensations because of stagnation in the gastrointestinal tract and abdominal distention.

Simethicone also works to shorten the movement time of vapor along the digestive tract. Therefore, Simeticone works to reduce symptoms caused by too much gas in the gastrointestinal tract in both adults and children, such as when swallowing a lot of gas into the stomach or some gases produced in the intestine due to the decalence of foods that are not digested by bacteria. Simeticone has been shown to have anti -Helicobacter pylori. The minimum inhibitory concentration (mic) of Simeticone for H. Pylori from 64 - 128 mg/liter, this concentration can be achieved in the stomach with a dose of treatment.

Mechanism of impact

Simethicone is a viscous liquid, matte, gray, containing 4-7% (KL/KL) Silicon Dioxyd. Its impact mechanism is to reduce the surface tension of the bubbles, making them combined. Simethicone is used to remove steam, gas or foam in the digestive tract before X -rays and to reduce abdominal and indigestion. Simethicone is excreted in non -change form.

Use therapy

To reduce painful pain due to excess steam in the digestive tract. Used as a substance that supports treatment for many diseases, including a slightly obstructive problem such as slightly obstructed after surgery, due to swallowing gas, indigestion, stomach ulcers, colon conclusion or stimulation. The usual dose for adults to use is 160 - 400 mg/day is divided into small doses, used after each meal and before going to bed. Simethicon is also used in combination with anti -acid, anti -spasms, sedatives and digestive drugs.

pharmacokinetics

Simethicone is a physiological inert substance; It does not seem to be absorbed through the gastrointestinal tract or obstructing gastric secretion or nutrient absorption. After oral, this drug is excreted in the form of unchanged.

Calculation

In rats: After drinking, subcutaneous injection, peritoneal injection, people do not notice any death. LD50> 35,000.

In Wistar rats: after drinking, subcutaneous injection, peritoneal injection. LD50> 12,000.

Simethicone is obviously not toxic and there is no report on side effects. Simethicone is recommended not to be used to treat abdominal pain in babies because there is very little information about the safety of drugs for babies and children.

Simethicone is not absorbed through the digestive tract, so it has no pharmacokinetic and bioavotodic activity. It does not cause harmful effects. Due to the non -absorbing nature, clinical reports are not noticed any clinical or toxic side effects. In addition, Simethicone is commonly prescribed in combination with antacids.

Clinical trial

The results obtained from a total of 130 children to prove the effectiveness and harmlessness of pharmaceutical products are used for 2-3 weeks.

In most cases, abdominal distention, seemingly due to digestive disorders, greatly reduced, have results on 1/2 cases in pain relief or stop vomiting.

In the case of vomiting of the gastric mood, the results obtained, based on a few cases, seems lower than other special preparations. With a higher dosage can bring better results. The intestinal intolerance for Simethicone allows double the dose, which increases the emulsion impact relatively low with a measurement unit mixed with meals.

In many cases of infection syndrome in children, this drug certainly has a favorable effect due to reducing abdominal distention and easily returns to normal eating habits. It may be a more important role because it is a protective substance against the digestive system lesions and easily the impact of enzymes, which may explain the special weight gain that is noticeable in some patients during the therapy.

Before taking Espumisan drugs treat symptoms of flatulence and bloating (2 blisters x 25 tablets)

How to use

Take oral use. You can use Espumisan 40 mg of the same or after meals, can also be used before going to bed if necessary.

Dosage

Symptoms with gas accumulation in the digestive tract (such as flatulence, bloating).

age Dosage

frequency of use

Big 2 capsules (equivalent to 80 mg Simeticone) 3 - 4 times/day.

can also use Espumisan Capsules after surgery. Espumisan Capsules for a long time. a day before testing morning testing day

(equivalent to 240 mg of simeticone).

2 capsules (equivalent to 80 mg of simeticone). Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.What do

do when overdose? Even with high doses of Espumisan Capsules still tolerated well without any symptoms.

The active ingredient Simeticone in Espumisan Capsules broke the air bubbles in the digestive tract completely according to the mere physical mechanism.

Simeticone does not absorb into the body and does not change chemically as well as biology during the flow process in the digestive tract.

What to do when you forget 1 dose?

If you have any questions about this medication, ask your doctor or pharmacist.

Side Effects

When using Espumisan 40 mg, you may experience unwanted effects (ADR).

So far, no unwanted effects have been recorded related to the use of Espumisan Capsules.

Yellow orange S (E110) color agent can cause allergic reactions.

methyl parahydroxybenzoate (E218) can cause hypersensitivity reactions, may also be late hypersensitivity reactions.

Please inform the doctor or pharmacist of unwanted effects when using the drug

Instructions on how to handle ADR

When experiencing side effects of the drug, it is necessary to stop using and notify the doctor or go to the nearest medical facility for timely treatment.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

Contraindicated

Espumisan 40 mg is contraindicated in the following cases:

Do not use Espumisan Capsules in case of sensitivity to simeticone, coloring - Yellow Orange S (E 110), Methyl parahydroxybenzoate (E218) or any excipients of the drug.

Be cautious when using

If the unpleasant symptoms at the new gastrointestinal tract appears and/or does not cure, you should visit the doctor to find the cause and detect the disease for treatment.

Do not take the drug after expiry. The expiry date is recorded on the medicine box and the blister. The expiry date is considered the last day of the month.

Do not cancel the drug by wastewater or household waste. Ask the pharmacist about how to cancel unused pills. This method will help protect the environment.

The ability to drive and operate machinery

No special caution.

During pregnancy and lactation

consult your doctor or pharmacist before taking any medication.

Because simeticone does not absorb through the gastrointestinal tract, Espumisan Capsules does not cause side effects when used for pregnant and lactating women.

There is no clinical data on the use of Espumisan Capsules for pregnant women.

Interactive drug

There is no interaction with other drugs.

Storage

To be out of reach of children.

Storage below 30 ° C.

Other drugs

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