Eye drops, nose polydoxanco Hataphar treat eye and nose infection (5ml)

Dosage form Bottle x 5ml
Specifications Dexamethasone sodium phosphate, chloramfenicol, excipients just enough

Ingredient

Composition information	Content
Dexamethasone sodium phosphate	5mg
Chloramfenicol	25mg
August excipients just enough	5ml

Uses

Indications

Polydoxancolic drugs are indicated in the following cases:

Inflammatory diseases in the eye, nose: eye pain, red eyes, itchy, watery eyes, rhinitis, sinusitis, treatment after eye surgery, nose.

Pharmacokology

Dexamethason: Dexamethasone has anti -inflammatory, anti -allergic, anti -inflammatory activity 25 times more powerful than hydrocortison. Like other anti -inflammatory glucocorticoids, one of the effects of dexamethasone is to inhibit phospholipase A2, the first stage of the prostaglandin synthesis process. Dexamethason also prevents the dynamic phenomenon of neutral polygon leukemia towards inflammation. Dexamethason is used on the spot such as in conjunctiva, outer ear canal or nasal mucosa to treat inflammatory symptoms or allergies in the outer or eye or eye. Eye corticosteroid therapy does not cure the disease, so it is necessary to identify or eliminate the cause of inflammation, if possible.

Chloramphenicol: An antibiotic with low molecular weight, mainly acting on Gram -positive, gram -negative, torsion, Salmonella, Chlamydia (Passive Eye). The mechanism of acting of chloramphenicol is inhibiting the bacterial protein synthesis.

naphazolin nitrate: is an α sympathetic medication that works to be contraction in place quickly, reducing swelling and congestion when the drug is small into the mucosa. When small into the conjunctiva, naphazoline causes shrinkage of arteries and temporarily reduces congestion, and may also be congested again. Naphazoline can cause pupils to relax when the eyes are small, but with the common concentration used as a hemolytic medicine in the eye, this effect is not significant. The drug has no effect in treating slow sensitivity such as dermatitis - conjunctiva due to contact.

pharmacokinetic

dexamethasone sodium phosphate: Within 10 to 20 minutes after a small dexamethasone dose, this drug will be present with high concentrations in the conjunctiva and cornea.

Chloramphenicol: Chloramphenicol penetrates very quickly into the cornea and can measure effective concentration in terms of treatment from 3 - 6 mcg/ml in the aquatic fluid after small drugs for 15-30 minutes. The half -life of chloramphenicol is 3-5 hours. In inflamed eyes, the time for the drug saved in the eye may be much shorter.

naphazolin nitrate: After the small naphazoline solution on the mucosa or conjunctiva, the vascular effect is reached for 10 minutes and lasts for about 2-6 hours. Sometimes the drug can absorb and cause systemic effect. No notice of distribution and elimination of drugs in small eye form.

Before taking Eye drops, nose polydoxanco Hataphar treat eye and nose infection (5ml)

How to use

eye drops - nose.

Dosage

Each time 2-3 drops, 4-5 times a day. In case of acute can be small 1 drop.

The vial has opened the button for only 14 days.

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.

What to do when overdose? In case of taking the wrong eye drops can cause the following symptoms: arrhythmia, pale, sweating, pupils and hypertension. Use specific measures to reduce absorption, no specific antagonists.

What to do when you forget a dose? However, if close to the next dose, skip the forgotten dose and take the next dose at the time as planned. Note that it should not be used double the prescribed dose.

Side Effects

When using Polydoxancol, you may experience unwanted effects (ADR).

The drug can cause local irritation, a slight mild feeling as soon as the drug is small, the drug may go down to the mouth, causing bitterness.

Taking drugs for weeks can cause glaucoma to recover in sensitive patients. Therefore, it is necessary to check the glaucoma regularly.

Long -sized treatment with corticosteroids can cause special systemic side effects in children. In some cases, corneal burns and cataracts.

Dehumidate disorders of partially recovered (anemia, reduced blood cell lines, leukopenia, thrombocytopenia, no granulocytes) have occurred in some individual cases after treatment with chloramphenicol eye small eyes. Serious side effects rarely occur when used on the spot naphazolin at the dose of treatment.

Although the vasoconstrictor is used in low doses in local drops, the same body -like effects can still occur, especially in children and the elderly. Chest drum, arrhythmia, hypertonic increase, headache, sweating, glaucoma and reaction congestion may occur.

Instructions on how to handle ADR

When experiencing side effects of the drug, it is necessary to stop using and notify the doctor or go to the nearest medical facility for timely treatment.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

Contraindicated

Polydoxancolin is indicated in the following cases:

Hypersensitivity to one of the ingredients of the drug.

Lateal ulcer, Herpes Simplex or other viruses in the eyes, eye fungus.

People with glaucoma disease, glaucoma.

Severe liver dysfunction and severe blood disease due to bone marrow failure, family history with bone marrow failure.

Pregnant women, babies.

TB infection, perforation of the eardrum.

Caution when using

Caution when used for women who are breastfeeding. Children under 2 years old, do not take the drug for a long time, repeat many times. After 7 - 8 days of treatment if the eye condition does not improve, it is necessary to consider choosing another treatment.

The ability to drive and operate machinery

The drug does not affect.

Pregnancy

chloramphenicol easily passes through the placenta fence and is secreted into breast milk. Therefore, it is not advisable to use medication for pregnant or lactating women because it can cause severe disability in infants or breastfed babies.

Breastfeeding period

Should not take medicine for women who are breastfeeding because chloramphenicol is easily secreted into breast milk.

Drug interaction

should not be used simultaneously chloramphenicol with bactericidal (penicillin, cephalosporin, gentamicin, tetracyclin, polymycin B, vancomycin or sulphadiazin). Also should not be used simultaneously with systemic medications that have side effects on hematopoietic systems. Sulphonylurea drugs, Coumarin derivatives, Hytantoins and Methotrexate.

Although less important, should also consider the known drug interactions for body corticosteroids.

Use sympathetic medications in general as well as naphazolin for patients who are taking Monoamine inhibitors, Maprotilin or 3 -round antidepressants that can cause mild hypertension.

Storage

In a dry place, temperatures below 30 ° C.

Other drugs

Disclaimer

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