Famotidin 40 Pharmacy 3-2 Treatment of peptic ulcer (10 blisters x 10 tablets)

Dosage form Box of 10 blisters x 10 tablets
Specifications Famotidine

Ingredient

Composition informationContent
Famotidine40mg

Uses

indications

Famotidin drugs are indicated in the following cases:

  • Treatment of peptic ulcer. Eat, histamine or pentagastrin. Histamine antagonistic activity in the receptor of Famotidine is slowly recovered, due to slow -separating drugs from receptors.

    Comparison by molecule of Famotidin is 20-150 times stronger than cimetidine and 3-20 times compared to ranitidin in inhibiting stomach acid secretion. After drinking, the anti -secreting effect starts within 1 hour, maximum effect depends on the dose, within 1-3 hours. With a dose of 20 to 40mg, the secretary time is 10 to 12 hours.

    Dynamic pharmacokinetics

    After drinking, Famotidin is absorbed incomplete in the digestive tract and bioavailability is about 40 - 45%. Famotidin metabolizes less in the head phase. After drinking, the maximum concentration in plasma is 1-3 hours. The concentration of drugs in plasma after using multiple doses is similar to the single dose, 15-20% Famotidin binds to plasma proteins.

    Half life eliminates 2.5 - 3.5 hours. Elimination through the kidneys 65 - 70% and through 30-35% metabolism. The clearance of the kidney is 250 - 450 ml/min, proving to be partially excreted in the renal tubules, 25-30% of oral dose and 65-70% of the intravenous dose in urine in the form of unchanged. The only metabolic substance determined in humans is S - Oxid.

    There is a close relationship between creatinine and half -life of the famotidine. In people with severe renal failure, creatinine clearance is less than 10 ml/minute, half -life is except for more than 20 hours, so the dose or distance between dose or distance is needed. Low -dose maintenance treatments H2 antihistamine drugs reduce the incidence of recurrent ulcers, but does not change the process of the disease when stopping the drug and must consider the treatment of H. pylori. Maintenance treatment is the most suitable for those who often recur several and for the elderly with ulcerative complications.

    • Before taking Famotidin 40 Pharmacy 3-2 Treatment of peptic ulcer (10 blisters x 10 tablets)

    How to use

    oral medication.

    Dosage

    Adults

    Take 1 capsule/day/day in the evening before going to bed or as directed by the physician

    Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.What to do when overdose?

    Symptoms

    has not been overdosed. In patients with gastric secretion, they have taken up to 800mg of Famotidin/day, and has not yet seen severe poisoning manifestations.

    Treatment

    Normal measures are drugs that have not absorbed as quickly as possible from the intestinal tract, symptomatic treatment and support should be done immediately. Clinical monitoring.

    What to do when you forget a dose? However, if close to the next dose, skip the forgotten dose and take the next dose at the time as planned. Note that it should not be used double the prescribed dose.

    Side Effects

    When using Famotidin, you may experience unwanted effects (ADR).

    Common
  • Body: headache, dizziness.
  • Systemic: Fever, fatigue, weakness. Including cramps, joint pain.
  • Cardiovascular: atrial clog, breast drum.

    Notice immediately to the doctor the unwanted effect when using the drug

    • Warnings

    Before using the drug you need to read the instructions carefully and refer to the information below.

    contraindicated

    famotidin drugs contraindicated in the following cases:

  • Sensitive to one of the ingredients of the drug.
  • Contraindications for children because of lack of research.

    • Caution when using

    responding to symptoms with Famotidin does not rule out the malignant properties of stomach ulcers. Famotidin should be used carefully in people with renal failure (creatinine clearance below 10 ml/minute) due to the main excretion of the kidneys. Needs to reduce the dose or increase between the dose.

    Except for the instructions of a physician, and patients self -treatment should stop the drug if there are still symptoms of heartburn (chest burning), increase gastric acid secretion, stomach burning after continuous treatment of drugs for 2 weeks without cure.

    Pregnant and lactating women.

    The ability to drive and operate machinery

    does not affect.

    Pregnancy

    should be cautious when using.

    Breastfeeding period

    should be cautious when using.

    Interactive drug

    Food and antacids: Foods increases slightly and antacids that mitigate the bioavailability of Famotidin, but these effects do not affect the clinical effect. Famotidin can also be combined with antacids.

    Storage

    Leave a cool dry place, temperatures below 30 ° C, avoiding light.

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