Femancia Medisun treat anemia due to iron deficiency and hematopoietic factors (6 blisters x 10 tablets)

Dosage form Box of 6 blisters x 10 tablets
Specifications Iron, folic acid

Ingredient

Composition informationContent
Iron100mg
Folic acid350mcg

Uses

Indications

Treatment of cases of anemia due to lack of supply or loss of iron and hematopoietic factors.

Cases of increasing hematopoietic demand such as pregnant women, lactating, malnutrition, postoperative period, serious recovery stage.

Pharmacology

iron fumarat: high iron content (33 important factors participating in structure

hemoglobin and oxidation of living tissues) are a component of pigmentation, there are many studies that support the hypotheses that the lack of iron has a disadvantageous impact on the ability to study and the ability to solve children's problems. Anemia children are treated with iron, increasing the rate of weight gain and improving mental skills (faster, accurate reaction) than children anemia using Placebo. When iron deficiency, the body not only changes hematopoiesis, but also changes the function of many important enzymes. Therefore, iron supplementation is a very important measure to treat weak anemia.

Folic acid: is a vitamin of Group B, in the body, it is reduced to tetrahydrofolate which is coenzyme of many metabolic processes including synthesis of nucleotides with Purin or Pyrimidine nuclei; Therefore, it affects DNA synthesis. When vitamin C, folic acid is converted into leucovorin, which is essential for DNA and RNA synthesis. Olic acid is an indispensable factor for nucleoprotein synthesis and normal red blood cells; Folic acid deficiency causes huge red blood cell anemia like anemia due to vitamin B12 deficiency.

Dynamic pharmacokinetics

iron fumarat:

absorption:

When drinking iron is absorbed at the duodenum and the head of the colon is about 5-10% of the oral intake into the body actively transporting. This ratio may increase to 20-30% if the iron reserve is deficient or increased the production of red blood cells. Food, phosphate, phylate can reduce iron absorption. The iron salts II are 3 times easier to absorb iron salts.

Distribution - Metabolism:

iron is metabolized in plasma in the form of transferrin to cell fluid, the most liver tissue and storage in the form of ferritin. Iron is put into bone oral bone to become a component of blood cells in red blood cells, into the body into a component of Myoglobin. The two largest iron reserves are red blood cells and endothelial hammock system.

Era:

iron is eliminated about 1mg/day in healthy men, most of the gastrointestinal tract (bile, mucosal cells are peeling), the rest of the skin and urine; In iron women with extra menstrual periods can be up to 2mg/day.

acid folic:

absorption:

Fast -released antidote in the stomach and absorb mainly at the beginning of the small intestine.

Distribution - Metabolism:

Folic acid in a normal diet is absorbed very quickly and distributes tissues in the body. The drug is stored mainly in the liver and is actively focused in cerebrospinal fluid.

Era:

Every day about 4-5 micrograms eliminate through urine. Drink high -dose folic acid causes vitamins eliminated through urine to increase in proportion. Folic acid passes through the placenta and is in breast milk.

Before taking Femancia Medisun treat anemia due to iron deficiency and hematopoietic factors (6 blisters x 10 tablets)

How to use

oral medication.

Dosage

Take the best drug when hungry. Can be used with food to reduce gastrointestinal discomfort.

Adults take 1 capsule/day before eating.

Children: Do not recommend use.

What to do when overdose? At this time, there was a period that seemed to recover, no symptoms, but after about 6-24 hours, symptoms reappeared with blood clots and cardiovascular collapse (heart failure due to myocardial lesions). Some manifestations such as: high fever, hypoglycemia, liver toxicity, kidney failure, convulsions and coma.

Easy to have a risk of intestinal perforation if taken high doses. In the recovery stage, there may be cirrhosis, pyloric stenosis. It may also be infected by Yersinia Enterocolica.

Treatment: gastric lavage with milk or carbonate solution. After washing the stomach, pump Deferoxamine solution into the stomach through the catheter. In the case of iron intake of over 60mg/kg of weight, or when there is severe symptoms, the first must give intravenous defaoxamin.

Intravenous injection dose of 15mg/kg/hour until the symptoms are over and until the concentration of Fe2+ decreases below 60micromol/liter. It is necessary to use higher doses. If you need to raise blood pressure using dopamine, it is required if there is kidney failure. Adjust the balance of base acid and electrolytes, and rehydration.

What to do when forgetting a dose?

Side Effects

Rare, ADR

Gastrointestinal tract: Abdominal pain, nausea, vomiting, constipation. Black feces (clinical significance).

Skin: itching, rash, urticaria.

Instructions on how to handle ADR

Can restrict non -regular ADR by taking low doses, then increasing gradually. However, when you see the strange phenomena, you have to stop using the medicine and consult the doctor or pharmacist.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

Contraindicated

Hypersensitivity to one of the ingredients of the drug, iron pigmentation, progressive stomach ulcers, repetitive blood transfusion, small intestinal inflammation, colitis, iron anemia.

Be cautious when using

iron Fumarat:

Be cautious when used for patients with suspected stomach ulcers, anise inflammation or chronic ulcer.

Duration of iron deficiency anemia treatment should not exceed 6 months.

Due to an iron deficiency anemia and vitamin B12 or folat deficiency may be micro -deficient disease, patients with platelet anemia intolerant to iron treatment should be checked to see if there is vitamin B2 or folat deficiency.

Folic acid:

Do not use separate folic acid or use in combination with vitamin B2 with insufficient doses to treat giant red blood cell anemia. Multi -vitamin preparations containing folic acid can be dangerous because of the actual deficiency level of vitamin B12 in huge red blood cell anemia due to vitamin B12 deficiency. Although folic acid can cause hematopoietic response in patients with giant red blood cell anemia due to vitamin B12 deficiency, it is still not allowed to use it alone in the case of vitamin B12 deficiency because it can promote semi -acute spinal cord degeneration.

Be careful in patients with folat tumors.

Lactose excipients cure: Patients with rare genetic disorders in galactose tolerance, Lactase Lapp deficiency or Glucose-Galactose absorption disorders should not use this drug.

People with normal blood iron to avoid prolonged medication. Stop taking the drug if not tolerated.

The effect of the drug on the ability to drive and operate machinery

drugs can be used for drivers and operating machinery.

Use drugs for women during pregnancy and lactation

The drug is used for this object.

Drug interaction

iron fumarat:

Do not combine drugs with antibiotics such as: Ofloxacin, Ciprofloxacin, Norfloxacin.

Take the same drug with antacids such as carbonate, sodium carbonate and magnesium trisilicat or tea water that can reduce iron absorption.

iron can chelate with tetracyclin and reduce the absorption of both drugs.

iron can reduce the absorption of penicilamin, carbidopa/levodopa, methyldopa, quinolones, thyroid hormones and zinc salts.

Folic acid:

The absorption of the drug may be reduced when taking the drug simultaneously with sulphasalazin.

Oral contraceptives reduce metabolism of folat and cause folat and vitamin B12 to a certain extent.

cotrimoxazole reduces the effect of treating red blood cells of folic acid

Storage

Leave a cool place, avoid light, temperatures below 30⁰C.

To be out of reach of children, read the instructions carefully before use.

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