Fenaflam DHG medicine treats acute pain inflammation (2 blisters x 10 tablets)

Dosage form Box of 2 blisters x 10 tablets
Specifications Diclofenac potassium

Ingredient

Composition information	Content
Diclofenac potassium	25mg

Uses

indications

Fenaflam drugs are indicated in the following cases:

Short -term treatment of acute pain inflammation such as dysmenorrhea, and acute inflammation in gynecological obstetrics, maxillofacial teeth, ear, nose and throat, migrain attacks, low joints, pain after trauma or after surgery. fever. The active inhibitor of cyclooxyqgenase, thus significantly reduces the formation of prostaglandin, prostacyclin and thrornboxan are inflammatory, pain and fever.

Dynamic pharmacology

diclofenac dissolves well in intestinal fluid, is easily absorbed through the gastrointestinal tract after drinking and achieves maximum concentrations in plasma, highly available.

The drug is very strong with plasma proteins (over 99%), mainly with albumin. DiClofenac easily penetrates the epidemic, the drug concentration here remains while plasma concentrations have decreased.

Half life in plasma is about 1-2 hours.

Half life eliminated from the epidemic fluid is 3 - 6 hours.

approximately 60% of the dose is discharged through the kidneys in the form of metabolic substances (glucuronid and sulphat conjugate) and a part of the activity and less than 1% in the original form of drugs; The rest is discharged through bile and feces.

The process of absorption, metabolism and elimination of drugs does not depend on age.

Before taking Fenaflam DHG medicine treats acute pain inflammation (2 blisters x 10 tablets)

How to use

Fenaflam drugs for oral use.

Dosage

To minimize the risk of adverse events, Fenaflam is required at the lowest daily daily dose in the shortest possible time.

Adults: Take 1-2 capsules x 2-3 times/day. In case of phosphate dysmenorrhea should take medicine before meals. Or as directed by the physician.

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.

What to do when overdose?

The common measure is to immediately cause vomiting or gastric lavage, followed by symptomatic and supportive treatment.

After gastric vomiting and active carbon can be used to reduce the absorption of the drug in the gastrointestinal tract and in the gastrointestinal cycle. Diuretic to treat Diclofenac poisoning is a suspicious measure, because the drug is highly attached to plasma proteins; However, diuretic may also be useful but need to closely monitor water -electrolytes because there may be serious disorders of electrolytes and water stasis.

What to do when you forget a dose? However, if close to the next dose, skip the forgotten dose and take the next dose at the time as planned. Note that it should not be used double the prescribed dose.

Side Effects

When using Fenaflam 25mg, you may experience unwanted effects (ADR).

Common, ADR> 1/100

Digestive: Nausea, vomiting, diarrhea, constipation, epigastric pain.

Less, 1/1000 ≤ ADR

No report.

Rare, 1/10000 ≤ ADR

Digestive: ulcers, gastrointestinal bleeding (in the case of prolonged treatment).

blood: blood disorders (hypotenosis, platelets, anemia). nerve: headache, insomnia, ease of irritation.

Skin and subcutaneous tissue: urticaria, edema. Respiratory: Asthma, bronchial spasm.

Eyes: blurred vision, eye pain, double look.

Urology: Acute renal failure, interstitial nephritis, hematuria.

Liver: Increased liver transaminase, hepatitis.

Heart thrombosis: Clinical and pharmaceutical tests show that the use of diclofenac is associated with an increase in the risk of cardiovascular thrombosis (such as myocardial or diverse infarction), especially when using diclofenac at high doses (150 mg/day) and extended.

Instructions on how to handle ADR

When experiencing side effects of the drug, it is necessary to stop using and notify the doctor or go to the nearest medical facility for timely treatment.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

Contraindicated

Fenaflam 25 mg is contraindicated in the following cases:

Hypersensitivity to one of the ingredients of the drug.

People with a history of allergies (asthma, rash, acute rhinitis, ...) with prostaglandin inhibitors or acetyl salicylic acid groups.

People with stomach ulcers, duodenum progressive or have a history of gastrointestinal bleeding.

People with bleeding, blood failure, kidney failure or severe liver, reducing the volume of circulatory, people with adhesive diseases.

Pregnant women do not use NSAID drugs in the last 3 months of pregnancy.

Patients with congestive heart failure (from degree to IV according to the function of heart failure according to the New York Heart Association - NYHA), ischemic heart disease, peripheral artery disease, cerebrovascular disease.

Caution when using

people with a history of ulcer, bleeding or puncture of the digestive tract. Patients with kidney failure, liver failure, lupus erythematosus. Need to monitor and test liver and kidney function when treated for a long time with NSAID drugs. Patients with hypertension or heart disease or edema. People infected. People with a history of coagulation disorders, bleeding.

Heart thrombosis

Non -steroid anti -inflammatory drugs (NSAIDs), non -aspirin, using systemic sugar can increase the risk of cardiovascular thrombosis, including myocardial and diverse infarction, which can lead to death. This risk can appear early in the first few weeks of taking the drug and can increase over time. The risk of cardiovascular thrombosis is recorded mainly at high doses.

Doctors need to periodically evaluate the appearance of cardiovascular events, even if the patient has no previous cardiovascular symptoms. Patients should be warned of symptoms of serious cardiovascular events and need to visit the doctor as soon as they appear.

To minimize the risk of adverse events, Fenaflam is needed at the lowest daily daily doses in the shortest possible time. Careful consideration should be considered when using diclofenac for patients with risk factors for significant cardiovascular events (such as hypertension, increased serum lipid, diabetes, tobacco addiction).

The ability to drive and operate machinery

Precautions while driving and operating machinery.

Pregnancy

only use drugs for these objects when really necessary. Do not use the drug in the last three months of pregnancy. People who intend to get pregnant should not use diclofenac.

Breastfeeding period

only use medicine for this object when really necessary.

Drug interaction

should not use Diclofenac in combination with:

Non -steroid anti -inflammatory drugs (NSAID), salicylate derivatives, glucocorticoids: Increased risk of ulcers, gastrointestinal bleeding.

anticoagulants heparin, cooumarin, ticlopidin: increase the risk of bleeding.

Quinolon antibiotics: increase side effects on the central nervous system of these antibiotics, leading to convulsions.

IUD: capable of reducing contraceptive effect.

lithium, digoxin: diclofenac increases the concentration of these substances in serum to toxicity. If it is required to coordinate, the lithium, digoxin dose must be adjusted during and after treatment with diclofenac and need to monitor the patient carefully about the level of lithium or digoxin in the blood.

methotrexate: Increasing the toxicity of methotrexate.

can coordinate but must monitor patients:

cyclosporin: Need to monitor kidney function.

Diuretics: The risk of secondary renal failure due to reduced blood flow to the kidneys.

Hypertension medications (transferred inhibitors, beta blockers, ...)

Anti -acid drugs: Reducing intestinal irritation by diclofenac but reducing the concentration of diclofenac in serum.

Note when coordinating:

cimetidin: Reduce a little concentration of diclofenac in serum but do not reduce the effect of this drug helps protect the duodenum, stomach avoid side effects of diclofenac.

Probenecid: Increases Diclofenac concentration doubled. This has good clinical effects in arthritis but can occur diclofenac poisoning, especially those with renal function.

Effect of waste uric acid - urinary is not affected. If necessary, reduce the diclofenac dose.

Storage

In a dry place, the temperature does not exceed 300C, avoiding light.

Other drugs

Disclaimer

Every effort has been made to ensure that the information provided by Drugslib.com is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Drugslib.com information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Drugslib.com does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Drugslib.com's drug information does not endorse drugs, diagnose patients or recommend therapy. Drugslib.com's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners.

The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Drugslib.com does not assume any responsibility for any aspect of healthcare administered with the aid of information Drugslib.com provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.