Fexofenadine 180-UST Treatment of allergic rhinitis, chronic urticaria (10 tablets)

Dosage form Film bag tablets
Specifications Box of 1 blister x 10 tablets
Ingredient Fexofenadin HCl

Ingredient

Thành phần cho 1 viên

Composition information	Content
Fexofenadin HCl	180mg

Uses

indications

Fexofenadine 180 medicine is indicated in the following cases:

Again the symptoms accompanied by allergic rhinitis such as sneezing, nose itchy nose, stuffy nose, rome/pharyngeal/throat.

Treatment of symptoms of chronic indefinitely urticaria, reducing itching and quantity of urticaria.

Pharmacy

Fexofenadine is a second -generation antihistamine, which has a specific antagonistic and selective effect on peripheral H1 receptors. The drug is a metabolic substance that is active of terfenadin but no longer toxic to the heart due to not inhibiting potassium channels associated with myocardial cytoplasm.

Fexofenadin does not have a significant effect on acetylcholin antagonism, dopamine antagonistic and no effect in inhibiting receptor alpha or beta - adrenergic. At the treatment dose, the drug does not cause sleep or affects the central nervous system. The drug has a fast and prolonged effect due to slow -attached drugs into H1 receptors, forming a sustainable complex and slowly separated.

pharmacokinetics

Good absorption drug when used oral. After taking a 60mg tablet, the peak concentration in the blood is about 142nanogam/ml, achieved after 2-3 hours. Food reduces the peak concentration in plasma by about 17% but does not slow down the time to reach the peak concentration of the drug.

The ratio of the plasma protein of the drug is 60 - 70%, mainly with albumin and alpha 1 - Glycoprotein acid. The distribution volume is 5.4 - 5.8 liters/kg. It is unclear whether the drug is through the placenta or excretion in breast milk, but when using terfenadin has detected fexofenadin is the metabolism of terfenadin in breast milk.

Fexofenadin does not pass the blood - brain barrier. Approximately 5% of the dose of the drug is metabolized. About 0.5 - 1.5% are metabolized in the liver thanks to the cytochrom P450 enzyme system into non -active substances. 3.5% are converted into methyl ester derivatives, mainly thanks to the intestinal bacteria.

Half of Fexofenadin elimination is about 14.4 % hours, longer in renal failure people. The drug excreted mainly in feces (approximately 80%), 11 - 12% of the dosage is eliminated through urine in constant form.

Before taking Fexofenadine 180-UST Treatment of allergic rhinitis, chronic urticaria (10 tablets)

How to use

drugs used by oral.

Take the tablet with a glass of water.

Dosage

Dosage and medication time for each specific case depending on the prescription of the treating doctor.

Dosage for adults and children over 12 years old

Allergic rhinitis 180mg/time/day.

Elderly and liver failure

No dose adjustment.

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.

What to do when overdose?

Use conventional measures to remove unprocessed drugs in the digestive tract. Support support and symptomatic treatment. Hemolysis is negligible in blood concentration (1.7%). There is no specific antidote.

In an emergency, call the 115 emergency center immediately or go to the nearest local health station.

What to do when forgetting a dose? However, if the time to relax with the next dose is too short, skip the dose and continue the calendar of the drug. Do not use double dose to compensate for missed dose.

Side Effects

When using Fexofenadin 180, you may experience unwanted effects (ADR).

In control clinical studies, the unwanted effect rate in the patient group using Fexofenadine is similar to the Placebo group. The unwanted effects of the drug are not affected by the dosage, age, gender and race of the patient.

Common

Sleep, fatigue, headache, insomnia, dizziness.

Nausea, indigestion.

Virus infection (colds, flu), dysmenorrhea, upper respiratory infections, itchy throat, cough, fever, otitis media, sinusitis and back pain.

rarely

Fear, sleep disorders, nightmares.

dry mouth, abdominal pain.

rarely

Ban, urticaria, itching.

Thich vascular, chest tightness, shortness of breath, redness, anaphylaxis.

How to handle

The unwanted effects of the drug are usually mild. Only 2.2% of patients have to stop the drug due to the unwanted effects of the drug.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

Contraindicated

Fexofenadine 180 drug contraindicated in the following cases:

Patients with a history of hypersensitivity to Fexofenadine.

Patients under 12 years old.

L car loop and operate machinery

The drug is less likely to cause drowsiness, but still need to be cautious when operating machinery or driving a train.

Pregnancy and nursing mothers

Caution for pregnant women, nursing women. Only use when really necessary.

Medicine interaction

Because the drug can reduce the effect of antacids containing aluminum and magnesium, the drug should be used for 2 hours apart.

Storage

Leave a cool place, avoid light, temperature below 30⁰C.

To be out of reach of children.

Expiry date: 36 months from the date of manufacture.

Other drugs

Disclaimer

Every effort has been made to ensure that the information provided by Drugslib.com is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Drugslib.com information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Drugslib.com does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Drugslib.com's drug information does not endorse drugs, diagnose patients or recommend therapy. Drugslib.com's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners.

The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Drugslib.com does not assume any responsibility for any aspect of healthcare administered with the aid of information Drugslib.com provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.