Fexofenadine 60 - HV treatment of seasonal allergic rhinitis, chronic urticaria (10 blisters x 10 tablets)

Dosage form Film bag tablets
Specifications Box of 10 blisters x 10 tablets
Ingredient Fexofenadin hydrochlorid
Indication Rhinitis, allergic rhinitis, eczema, itching, atopic dermatitis, contact dermatitis

Ingredient

Composition information	Content
Fexofenadin hydrochlorid	60mg

Uses

Indications

Fexofenadin 60mg drug is indicated in the following cases:

Again the symptoms accompanied by allergic rhinitis such as sneezing, nose itchy nose, stuffy nose, rome/pharyngeal/throat.

Treatment of symptoms of chronic indefinitely urticaria, reducing itching and quantity of urticaria.

Pharmacy

Fexofenadine is a second -generation antihistamine, which has a specific antagonistic and selective effect on peripheral H1 receptors. The drug is a metabolic substance that is active of terfenadin but no longer toxic to the heart due to not inhibiting potassium channels associated with myocardial cytoplasm.

Fexofenadin does not have a significant effect on acetylcholin antagonism, dopamine antagonistic and no effect in inhibiting receptor alpha or beta - adrenergic. At the treatment dose, the drug does not cause sleep or affects the central nervous system. The drug has a fast and prolonged effect due to slow -attached drugs into H1 receptors, forming a sustainable complex and slowly separated.

pharmacokinetics

Good absorption drug when used oral. After taking 1 60 mg tablet, the blood peak concentration is about 142 nanogam/ ml, achieved after 2-3 hours. Food reduces the peak concentration in plasma by about 17% but does not slow down the time to reach the peak concentration of the drug.

The ratio of the plasma protein of the drug is 60 - 70%, mainly with albumin and alpha 1 - Glycoprotein acid. The distribution volume is 5.4 - 5.8 liters/ kg. It is unclear whether the drug is through the placenta or excretion in breast milk, but when using terfenadin has detected fexofenadin is the metabolism of terfenadin in breast milk.

Fexofenadin does not go through blood-flabbit barriers. Approximately 5% of the dose of the drug is metabolized. About 0.5 - 1.5% are metabolized in the liver thanks to the cytochrom P450 enzyme system into non -active substances. 3.5% are converted into methyl ester derivatives, mainly thanks to the intestinal bacteria. Half -life elimination of fexofenadin is about 14.4 % hours, longer in kidney failure.

Mainly eliminated drugs (approximately 80%), 11 - 12% of the dose is eliminated in urine in constant form.

Before taking Fexofenadine 60 - HV treatment of seasonal allergic rhinitis, chronic urticaria (10 blisters x 10 tablets)

How to use

drugs used by oral.

Take the tablet with a glass of water.

Dosage

Dosage and medication time for each specific case depending on the prescription of the treating doctor.

Dosage for adults and children over 12 years: allergic rhinitis 60mg/2 times/day;

Patients with renal failure: Starting treatment 1 tablet 60mg x 1 time/day;

Elderly and liver failure: No dose adjustment;

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.

What to do when overdose?

Use conventional measures to remove unprocessed drugs in the digestive tract. Support support and symptomatic treatment. Hemolysis is negligible in blood concentration (1.7%). There is no specific antidote.

In an emergency, call the 115 emergency center immediately or go to the nearest local health station.

What to do when forgetting a dose? However, if the time to relax with the next dose is too short, skip the dose and continue the calendar of the drug. Do not use double dose to compensate for missed dose.

Side Effects

When using Fexofenadin 60mg, you may experience unwanted effects (ADR).

In control clinical studies, the unwanted effect rate in the patient group using Fexofenadine is similar to the Placebo group. The unwanted effects of the drug are not affected by the dosage, age, gender and race of the patient.

Common:

Drowsy, tired, headache, insomnia, dizziness;

Nausea, indigestion;

viral infection (colds, flu), dysmenorrhea, upper respiratory infection, itchy throat, cough, fever, otitis media, sinusitis and back pain;

Uncommon:

Fear, sleep disorders, nightmares;

dry mouth, abdominal pain;

Rare:

Ban, urticaria, itching;

eagown, chest tightness, shortness of breath, redness, anaphylaxis;

How to handle:

The unwanted effects of the drug are usually mild. Only 2.2% of patients have to stop the drug due to the unwanted effects of the drug.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

Contraindicated

Fexofenadin 60mg contraindications in the following cases:

Patients with a history of hypersensitivity to Fexofenadine;

Patients under 12 years old;

Precautions when using

The effect of drugs when driving and operating machinery

The drug is less likely to cause drowsiness, but still need to be cautious when operating machinery or driving.

Pregnancy and nursing mothers

Caution for pregnant women, nursing women. Only use when really necessary.

Medicine interaction

Because the drug can reduce the effect of antacids containing aluminum and magnesium, the drug should be used for 2 hours apart.

Storage

Leave a cool place, avoid light, temperature below 30⁰C.

To be out of reach of children.

Expiry date: 36 months from the date of manufacture.

(USA Pharma USA Joint Stock Company is a supplier of pharmaceutical products, processing and franchise production to domestic and foreign partners.

The company's products are distributed nationwide with many recognized brands. Recently, the company's products have been present in neighboring countries such as Cambodia and Laos. Promoting market penetration Macau, Hong Kong, Philippines.

The company currently has 03 main workshops including: Cephalosporin workshop with the forms of hard -working capsules, tablets, film tablets; Powder, nuggets. Betalactam young workshop with the form of making hard capsules, soft capsules, tablets, film tablets, sugar tablets, effervescent tablets; Powder, nuggets, effervescent powder, effervescent nuggets; Cream, fat, and external gel; external broth medicine; Drug water. Health protection food chain with forms of tablets, film tablets, effervescent tablets, hard capsules, soft capsules, powder.

Currently USP Company is producing and circulating nationwide nearly 400 products, divided into 11 treatment groups: antibiotics, reducing fever pain; Anti -inflammatory analgesic; Business-Capital; cough - long sputum; antihistamine - anti -allergy; Nervous system - cardiovascular; digestive - liver bile; Vitamin - minerals; topical; Health protection food).

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